[Term]
id: PR:Q8N5V2-1
name: ephexin-1 isoform h1 (human)
def: "An ephexin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5V2-1." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-sequence.
synonym: "hNGEF/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8N5V2-1
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048600
name: ephexin-1 phosphorylated 1 (human)
def: "An ephexin-1 (human) that has been post-translationally modified to include phosphotyrosine at position 179 of the amino acid sequence represented by UniProtKB:Q8N5V2. UniProtKB:Q8N5V2, Tyr-179, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928441]
comment: Category=organism-modification.
synonym: "hNGEF/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8N5V2, Tyr-179, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928441 "PR:000048600 located_in GO:0005829"
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8N5V2-3
name: ephexin-1 isoform h3 (human)
def: "An ephexin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5V2-3." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-sequence.
synonym: "hNGEF/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8N5V2-3
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8N5V2
name: ephexin-1 (human)
def: "An ephexin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-gene.
synonym: "NGEF" RELATED Gene-based [UniProtKB:Q8N5V2]
synonym: "hNGEF" EXACT PRO-short-label [PRO:DNx]
synonym: "Eph-interacting exchange protein (human)" EXACT [UniProtKB:Q8N5V2]
synonym: "neuronal guanine nucleotide exchange factor (human)" EXACT [UniProtKB:Q8N5V2]
xref: UniProtKB:Q8N5V2
xref: Reactome:R-HSA-3006800 "PR:Q8N5V2 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011193 ! ephexin-1
relationship: has_gene_template HGNC:7807 ! NGEF (human)

[Term]
id: PR:Q8N5V2-2
name: ephexin-1 isoform h2 (human)
def: "An ephexin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5V2-2." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-sequence.
synonym: "hNGEF/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8N5V2-2
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000011193
name: ephexin-1
def: "A protein that is a translation product of the human NGEF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NGEF" EXACT PRO-short-label [PRO:DNx]
synonym: "Eph-interacting exchange protein" EXACT []
synonym: "neuronal guanine nucleotide exchange factor" EXACT []
is_a: PR:000000001 ! protein