[Term] id: PR:000011140 name: neogenin def: "A protein that is a translation product of the human NEO1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "NGN" RELATED Gene-based [] synonym: "NEO1" EXACT PRO-short-label [PRO:DNx] synonym: "IGDCC2" RELATED Gene-based [] synonym: "immunoglobulin superfamily DCC subclass member 2" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000057802 name: neogenin O-glycosylated 1 (human) def: "A neogenin (human) that has been O-glycosylated at the residue equivalent to Thr-434 of the amino acid sequence represented by UniProtKB:Q92859-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q92859-1, Thr-434, MOD:00005~GNO:G29068FM." [GlyGen:Q92859-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hNEO1/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q92859-1, Thr-434, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q92859 ! neogenin (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057803 name: neogenin O-glycosylated 2 (human) def: "A neogenin (human) that has been O-glycosylated at the residue equivalent to Thr-434 of the amino acid sequence represented by UniProtKB:Q92859-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q92859-1, Thr-434, MOD:00005~GNO:G43417UB." [GlyGen:Q92859-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hNEO1/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q92859-1, Thr-434, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q92859 ! neogenin (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057804 name: neogenin O-glycosylated 3 (human) def: "A neogenin (human) that has been O-glycosylated at the residue equivalent to Thr-434 of the amino acid sequence represented by UniProtKB:Q92859-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q92859-1, Thr-434, MOD:00005~GNO:G53434XO." [GlyGen:Q92859-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hNEO1/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q92859-1, Thr-434, MOD:00005~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q92859 ! neogenin (human) relationship: has_part GNO:G53434XO ! G53434XO relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057805 name: neogenin O-glycosylated 4 (human) def: "A neogenin (human) that has been O-glycosylated at the residue equivalent to Thr-846 of the amino acid sequence represented by UniProtKB:Q92859-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q92859-1, Thr-846, MOD:00005~GNO:G43417UB." [GlyGen:Q92859-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hNEO1/OGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q92859-1, Thr-846, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q92859 ! neogenin (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048581 name: neogenin, signal peptide removed form (human) def: "A neogenin (human) that has had the signal peptide removed. UniProtKB:Q92859, 34-1461." [PRO:DNx, Reactome:R-HSA-197623] comment: Category=organism-modification. synonym: "hNEO1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015043" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q92859, 34-1461" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-197623 "PR:000048581 located_in GO:0005886" intersection_of: PR:Q92859 ! neogenin (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92859 name: neogenin (human) def: "A neogenin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92859] comment: Category=organism-gene. synonym: "NGN" RELATED Gene-based [UniProtKB:Q92859] synonym: "NEO1" RELATED Gene-based [UniProtKB:Q92859] synonym: "hNEO1" EXACT PRO-short-label [PRO:DNx] synonym: "IGDCC2" RELATED Gene-based [UniProtKB:Q92859] synonym: "immunoglobulin superfamily DCC subclass member 2 (human)" EXACT [UniProtKB:Q92859] xref: UniProtKB:Q92859 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000011140 ! neogenin relationship: has_gene_template HGNC:7754 ! NEO1 (human) [Term] id: PR:Q92859-4 name: neogenin isoform h4 (human) def: "A neogenin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92859-4." [PRO:DNx, UniProtKB:Q92859] comment: Category=organism-sequence. synonym: "hNEO1/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q92859-4 is_a: PR:Q92859 ! neogenin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92859-2 name: neogenin isoform h2 (human) def: "A neogenin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92859-2." [PRO:DNx, UniProtKB:Q92859] comment: Category=organism-sequence. synonym: "hNEO1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q92859-2 is_a: PR:Q92859 ! neogenin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92859-3 name: neogenin isoform h3 (human) def: "A neogenin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92859-3." [PRO:DNx, UniProtKB:Q92859] comment: Category=organism-sequence. synonym: "hNEO1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q92859-3 is_a: PR:Q92859 ! neogenin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92859-1 name: neogenin isoform h1 (human) def: "A neogenin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92859-1." [PRO:DNx, UniProtKB:Q92859] comment: Category=organism-sequence. synonym: "hNEO1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q92859-1 is_a: PR:Q92859 ! neogenin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens