[Term]
id: PR:O14777-1
name: kinetochore protein NDC80 homolog isoform 1 (human)
def: "A kinetochore protein NDC80 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hNDC80/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14777-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038002 ! kinetochore protein NDC80 isoform 1

[Term]
id: PR:O14777
name: kinetochore protein NDC80 (human)
def: "A kinetochore protein NDC80 that is encoded in the genome of human." [PMID:17785528, PMID:20624902, PRO:KER]
comment: Category=organism-gene.
synonym: "HEC" RELATED Gene-based [UniProtKB:O14777]
synonym: "HEC1" RELATED Gene-based [UniProtKB:O14777]
synonym: "KNTC2" RELATED Gene-based [UniProtKB:O14777]
synonym: "NDC80" RELATED Gene-based [UniProtKB:O14777]
synonym: "HsHec1" EXACT [UniProtKB:O14777]
synonym: "hNDC80" EXACT PRO-short-label [PRO:DNx]
synonym: "kinetochore protein Hec1 (human)" EXACT [UniProtKB:O14777]
synonym: "kinetochore-associated protein 2 (human)" EXACT [UniProtKB:O14777]
synonym: "highly expressed in cancer protein (human)" EXACT [UniProtKB:O14777]
synonym: "retinoblastoma-associated protein HEC (human)" EXACT [UniProtKB:O14777]
xref: Reactome:R-HSA-375314 "PR:O14777 located_in GO:0005829"
xref: UniProtKB:O14777
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011050 ! kinetochore protein NDC80
relationship: has_gene_template HGNC:16909 ! NDC80 (human)

[Term]
id: PR:000011050
name: kinetochore protein NDC80
def: "A protein that is a translation product of the human NDC80 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HEC" RELATED Gene-based []
synonym: "HEC1" RELATED Gene-based []
synonym: "Hec1" EXACT []
synonym: "KNTC2" RELATED Gene-based []
synonym: "NDC80" EXACT PRO-short-label [PRO:DNx]
synonym: "kinetochore protein Hec1" EXACT []
synonym: "kinetochore-associated protein 2" EXACT []
synonym: "highly expressed in cancer protein" EXACT []
synonym: "retinoblastoma-associated protein HEC" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000045569
name: kinetochore protein NDC80 phosphorylated 1 (human)
def: "A kinetochore protein NDC80 (human) that has been phosphorylated at Ser-165. UniProtKB:O14777, Ser-165, MOD:00046." [PMID:18297113, PMID:21832156, iPTMnet:O14777]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18297113, PMID:21832156). Status=unreviewed.
synonym: "hNDC80/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14777, Ser-165, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O14777 ! kinetochore protein NDC80 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens