[Term]
id: PR:000011042
name: nuclear receptor coactivator 3
def: "A protein that is a translation product of the human NCOA3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ACTR" EXACT []
synonym: "AIB1" RELATED Gene-based []
synonym: "RAC3" RELATED Gene-based []
synonym: "pCIP" EXACT []
synonym: "AIB-1" EXACT []
synonym: "NCOA3" EXACT PRO-short-label [PRO:DNx]
synonym: "RAC-3" EXACT []
synonym: "SRC-3" EXACT []
synonym: "TRAM1" RELATED Gene-based []
synonym: "p/CIP" EXACT []
synonym: "NCoA-3" EXACT []
synonym: "TRAM-1" EXACT []
synonym: "BHLHE42" RELATED Gene-based []
synonym: "bHLHe42" EXACT []
synonym: "CBP-interacting protein" EXACT []
synonym: "receptor-associated coactivator 3" EXACT []
synonym: "amplified in breast cancer 1 protein" EXACT []
synonym: "steroid receptor coactivator protein 3" EXACT []
synonym: "class E basic helix-loop-helix protein 42" EXACT []
synonym: "amplified in breast cancer-1 protein homolog" EXACT []
synonym: "thyroid hormone receptor activator molecule 1" EXACT []
xref: IUPHARobj:2695
is_a: PR:000000001 ! protein

[Term]
id: PR:000027698
name: nuclear receptor coactivator 3 isoform 1 phosphorylated 4 (human)
def: "A nuclear receptor coactivator 3 isoform 1 phosphorylated 4 in human. UniProtKB:Q9Y6Q9-1, Ser-857, MOD:00046." [PMID:15383283, PRO:PD]
comment: Category=organism-modification.
synonym: "hNCOA3/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6Q9-1, Ser-857, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027697 ! nuclear receptor coactivator 3 isoform 1 phosphorylated 4
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027692
name: nuclear receptor coactivator 3 isoform 1 phosphorylated 1 (human)
def: "A nuclear receptor coactivator 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046." [PMID:18922467, PMID:21577200, PRO:PD]
comment: Category=organism-modification.
synonym: "hNCOA3/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027691 ! nuclear receptor coactivator 3 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027887
name: nuclear receptor coactivator 3 isoform 1 acetylated 2 (human)
def: "A nuclear receptor coactivator 3 isoform 1 acetylated 2 in human. UniProtKB:Q9Y6Q9-1, Lys-687, MOD:00064." [PMID:19608861, PRO:PD]
comment: Category=organism-modification.
synonym: "NCOA3-acLys687" EXACT []
synonym: "hNCOA3/iso:1/Ac:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6Q9-1, Lys-687, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027886 ! nuclear receptor coactivator 3 isoform 1 acetylated 2
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000027696
name: nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human)
def: "A nuclear receptor coactivator 3 isoform 1 phosphorylated 3 in human. UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048." [PMID:18765637, PRO:PD]
comment: Category=organism-modification. Kinase=("ABL1"; PR:P00519-1).
synonym: "hNCOA3/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027695 ! nuclear receptor coactivator 3 isoform 1 phosphorylated 3
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000027885
name: nuclear receptor coactivator 3 isoform 1 acetylated 1 (human)
def: "A nuclear receptor coactivator 3 isoform 1 acetylated 1 in human. UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064." [PMID:10490106, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:Q09472).
synonym: "hNCOA3/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "NCOA3-acLys619-acLys620" EXACT []
synonym: "UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027884 ! nuclear receptor coactivator 3 isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:Q9Y6Q9-2
name: nuclear receptor coactivator 3 isoform h2 (human)
def: "A nuclear receptor coactivator 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Q9-2." [PRO:DNx, UniProtKB:Q9Y6Q9]
comment: Category=organism-sequence.
synonym: "hNCOA3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6Q9-2
is_a: PR:Q9Y6Q9 ! nuclear receptor coactivator 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048530
name: nuclear receptor coactivator 3 phosphorylated 4 (human)
def: "A nuclear receptor coactivator 3 (human) that has been post-translationally modified to include phosphoserine at position 857 of the amino acid sequence represented by UniProtKB:Q9Y6Q9. UniProtKB:Q9Y6Q9, Ser-857, MOD:00046." [PRO:DNx, Reactome:R-HSA-5687005]
comment: Category=organism-modification.
synonym: "hNCOA3/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6Q9, Ser-857, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5687005 "PR:000048530 located_in GO:0005654"
is_a: PR:Q9Y6Q9 ! nuclear receptor coactivator 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6Q9-5
name: nuclear receptor coactivator 3 isoform h5 (human)
def: "A nuclear receptor coactivator 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Q9-5." [PRO:DNx, UniProtKB:Q9Y6Q9]
comment: Category=organism-sequence.
synonym: "hNCOA3/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6Q9-5
is_a: PR:Q9Y6Q9 ! nuclear receptor coactivator 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027694
name: nuclear receptor coactivator 3 isoform 1 phosphorylated 2 (human)
def: "A nuclear receptor coactivator 3 isoform 1 phosphorylated 2 in human. UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046." [PMID:19339517, PRO:PD]
comment: Category=organism-modification. Kinase=("CSNK1D"; PR:P48730).
synonym: "hNCOA3/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027693 ! nuclear receptor coactivator 3 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:Q9Y6Q9-4
name: nuclear receptor coactivator 3 isoform h4 (human)
def: "A nuclear receptor coactivator 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Q9-4." [PRO:DNx, UniProtKB:Q9Y6Q9]
comment: Category=organism-sequence.
synonym: "hNCOA3/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6Q9-4
is_a: PR:Q9Y6Q9 ! nuclear receptor coactivator 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6Q9-3
name: nuclear receptor coactivator 3 isoform h3 (human)
def: "A nuclear receptor coactivator 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Q9-3." [PRO:DNx, UniProtKB:Q9Y6Q9]
comment: Category=organism-sequence.
synonym: "hNCOA3/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6Q9-3
is_a: PR:Q9Y6Q9 ! nuclear receptor coactivator 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6Q9
name: nuclear receptor coactivator 3 (human)
def: "A nuclear receptor coactivator 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y6Q9]
comment: Category=organism-gene.
synonym: "AIB1" RELATED Gene-based [UniProtKB:Q9Y6Q9]
synonym: "RAC3" RELATED Gene-based [UniProtKB:Q9Y6Q9]
synonym: "NCOA3" RELATED Gene-based [UniProtKB:Q9Y6Q9]
synonym: "TRAM1" RELATED Gene-based [UniProtKB:Q9Y6Q9]
synonym: "hNCOA3" EXACT PRO-short-label [PRO:DNx]
synonym: "BHLHE42" RELATED Gene-based [UniProtKB:Q9Y6Q9]
synonym: "ACTR (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "pCIP (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "AIB-1 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "RAC-3 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "SRC-3 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "NCoA-3 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "TRAM-1 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "CBP-interacting protein (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "receptor-associated coactivator 3 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "amplified in breast cancer 1 protein (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "steroid receptor coactivator protein 3 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "class E basic helix-loop-helix protein 42 (human)" EXACT [UniProtKB:Q9Y6Q9]
synonym: "thyroid hormone receptor activator molecule 1 (human)" EXACT [UniProtKB:Q9Y6Q9]
xref: UniProtKB:Q9Y6Q9
xref: Reactome:R-HSA-442488 "PR:Q9Y6Q9 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011042 ! nuclear receptor coactivator 3
relationship: has_gene_template HGNC:7670 ! NCOA3 (human)

[Term]
id: PR:Q9Y6Q9-1
name: nuclear receptor coactivator 3 isoform 1 (human)
def: "A nuclear receptor coactivator 3 isoform 1 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-sequence.
synonym: "hNCOA3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6Q9-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027689 ! nuclear receptor coactivator 3 isoform 1