[Term]
id: PR:O60934
name: nibrin (human)
def: "A nibrin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60934]
comment: Category=organism-gene.
synonym: "NBN" RELATED Gene-based [UniProtKB:O60934]
synonym: "NBS" RELATED Gene-based [UniProtKB:O60934]
synonym: "P95" RELATED Gene-based [UniProtKB:O60934]
synonym: "NBS1" RELATED Gene-based [UniProtKB:O60934]
synonym: "hNBN" EXACT PRO-short-label [PRO:DNx]
synonym: "cell cycle regulatory protein p95 (human)" EXACT [UniProtKB:O60934]
synonym: "nijmegen breakage syndrome protein 1 (human)" EXACT [UniProtKB:O60934]
xref: Reactome:R-HSA-5684005 "PR:O60934 located_in GO:0005829"
xref: UniProtKB:O60934
xref: Reactome:R-HSA-75163 "PR:O60934 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011014 ! nibrin
relationship: has_gene_template HGNC:7652 ! NBN (human)

[Term]
id: PR:000011014
name: nibrin
def: "A protein that is a translation product of the human NBN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NBN" EXACT PRO-short-label [PRO:DNx]
synonym: "NBS" RELATED Gene-based []
synonym: "P95" RELATED Gene-based []
synonym: "NBS1" RELATED Gene-based []
synonym: "cell cycle regulatory protein p95" EXACT []
synonym: "nijmegen breakage syndrome protein 1" EXACT []
synonym: "nijmegen breakage syndrome protein 1 homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000045603
name: nibrin phosphorylated 1 (human)
def: "A nibrin (human) that has been phosphorylated at Ser-343. UniProtKB:O60934, Ser-343, MOD:00046." [PMID:10766245, PMID:10802669, iPTMnet:O60934]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10766245, PMID:10802669). Status=unreviewed.
synonym: "hNBN/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O60934, Ser-343, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-75237 "PR:000045603 located_in GO:0005654"
is_a: PR:O60934 ! nibrin (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens