[Term]
id: PR:000036287
name: myosin regulatory light chain 12B acetylated 1 (mouse)
def: "A myosin regulatory light chain 12B (mouse) that is N-terminal Met acetylated. UniProtKB:Q3THE2, Met-1, MOD:00058." [TDR:9382]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "mMYL12B/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q3THE2, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:9382
is_a: PR:Q3THE2 ! myosin regulatory light chain 12B (mouse)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000038025
name: myosin regulatory light chain 12B isoform 1
def: "A myosin regulatory light chain 12B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14950-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "MYL12B/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010842 ! myosin regulatory light chain 12B

[Term]
id: PR:P18666
name: myosin regulatory light chain 12B (rat)
def: "A myosin regulatory light chain 12B that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Mrlc2" RELATED Gene-based [UniProtKB:P18666]
synonym: "Mrlcb" RELATED Gene-based [UniProtKB:P18666]
synonym: "Myl12b" RELATED Gene-based [UniProtKB:P18666]
synonym: "Mylc2b" RELATED Gene-based [UniProtKB:P18666]
synonym: "rMYL12B" EXACT PRO-short-label [PRO:DNx]
synonym: "MLC-2 (rat)" RELATED [UniProtKB:P18666]
synonym: "MLC20 (rat)" EXACT [UniProtKB:P18666]
synonym: "myosin RLC-B (rat)" EXACT [UniProtKB:P18666]
synonym: "myosin regulatory light chain MRLC2 (rat)" EXACT [UniProtKB:P18666]
synonym: "myosin regulatory light chain 20 kDa (rat)" EXACT [UniProtKB:P18666]
synonym: "myosin regulatory light chain 2-B, smooth muscle isoform (rat)" EXACT [UniProtKB:P18666]
xref: UniProtKB:P18666
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010842 ! myosin regulatory light chain 12B
relationship: has_gene_template RGD:628855 ! Myl12b (rat)

[Term]
id: PR:Q3THE2
name: myosin regulatory light chain 12B (mouse)
def: "A myosin regulatory light chain 12B that is encoded in the genome of mouse." [OMA:Q3THE2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mrlc2" RELATED Gene-based [UniProtKB:Q3THE2]
synonym: "Myl12b" RELATED Gene-based [UniProtKB:Q3THE2]
synonym: "Mylc2b" RELATED Gene-based [UniProtKB:Q3THE2]
synonym: "mMYL12B" EXACT PRO-short-label [PRO:DNx]
synonym: "MLC20 (mouse)" EXACT [UniProtKB:Q3THE2]
synonym: "myosin regulatory light chain MRLC2 (mouse)" EXACT [UniProtKB:Q3THE2]
synonym: "myosin regulatory light chain 20 kDa (mouse)" EXACT [UniProtKB:Q3THE2]
synonym: "myosin regulatory light chain 2-B, smooth muscle isoform (mouse)" EXACT [UniProtKB:Q3THE2]
xref: UniProtKB:Q3THE2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010842 ! myosin regulatory light chain 12B
relationship: has_gene_template MGI:107494 ! Myl12b (mouse)

[Term]
id: PR:000010842
name: myosin regulatory light chain 12B
def: "A protein that is a translation product of the human MYL12B gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MLC-2" BROAD [PRO:DNx]
synonym: "MLC20" EXACT []
synonym: "MRLC2" RELATED Gene-based []
synonym: "MLC-2A" EXACT []
synonym: "MYL12B" EXACT PRO-short-label [PRO:DNx]
synonym: "MYLC2B" RELATED Gene-based []
synonym: "SHUJUN-1" EXACT []
synonym: "myosin regulatory light chain MRLC2" EXACT []
synonym: "myosin regulatory light chain 20 kDa" EXACT []
synonym: "myosin regulatory light chain 2-B, smooth muscle isoform" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q3THE2-1
name: myosin regulatory light chain 12B isoform 1 (mouse)
def: "A myosin regulatory light chain 12B isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMYL12B/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3THE2-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038025 ! myosin regulatory light chain 12B isoform 1

[Term]
id: PR:O14950
name: myosin regulatory light chain 12B (human)
def: "A myosin regulatory light chain 12B that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14950]
comment: Category=organism-gene.
synonym: "MRLC2" RELATED Gene-based [UniProtKB:O14950]
synonym: "MYL12B" RELATED Gene-based [UniProtKB:O14950]
synonym: "MYLC2B" RELATED Gene-based [UniProtKB:O14950]
synonym: "hMYL12B" EXACT PRO-short-label [PRO:DNx]
synonym: "MLC-2 (human)" BROAD [UniProtKB:O14950]
synonym: "MLC20 (human)" EXACT [UniProtKB:O14950]
synonym: "MLC-2A (human)" EXACT [UniProtKB:O14950]
synonym: "SHUJUN-1 (human)" EXACT [UniProtKB:O14950]
synonym: "myosin regulatory light chain MRLC2 (human)" EXACT [UniProtKB:O14950]
synonym: "myosin regulatory light chain 20 kDa (human)" EXACT [UniProtKB:O14950]
synonym: "myosin regulatory light chain 2-B, smooth muscle isoform (human)" EXACT [UniProtKB:O14950]
xref: Reactome:R-HSA-390727 "PR:O14950 located_in GO:0005829"
xref: UniProtKB:O14950
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010842 ! myosin regulatory light chain 12B
relationship: has_gene_template HGNC:29827 ! MYL12B (human)

[Term]
id: PR:O14950-1
name: myosin regulatory light chain 12B isoform 1 (human)
def: "A myosin regulatory light chain 12B isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMYL12B/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14950-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038025 ! myosin regulatory light chain 12B isoform 1

[Term]
id: PR:000048497
name: myosin regulatory light chain 12B phosphorylated 2 (human)
def: "A myosin regulatory light chain 12B (human) that has been post-translationally modified to include phosphothreonine at position 19, and phosphoserine at position 20 of the amino acid sequence represented by UniProtKB:O14950. UniProtKB:O14950, Thr-19, MOD:00047|Ser-20, MOD:00046." [PRO:DNx, Reactome:R-HSA-390751]
comment: Category=organism-modification.
synonym: "hMYL12B/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14950, Thr-19, MOD:00047|Ser-20, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-390751 "PR:000048497 located_in GO:0005829"
is_a: PR:O14950 ! myosin regulatory light chain 12B (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048496
name: myosin regulatory light chain 12B phosphorylated 1 (human)
def: "A myosin regulatory light chain 12B (human) that has been post-translationally modified to include phosphothreonine at position 19 of the amino acid sequence represented by UniProtKB:O14950. UniProtKB:O14950, Thr-19, MOD:00047." [PRO:DNx, Reactome:R-HSA-5668936]
comment: Category=organism-modification.
synonym: "hMYL12B/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14950, Thr-19, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5668936 "PR:000048496 located_in GO:0005829"
is_a: PR:O14950 ! myosin regulatory light chain 12B (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036882
name: myosin regulatory light chain 12B phosphorylated 1 (mouse)
def: "A myosin regulatory light chain 12B that has been phosphorylated on a Thr residue in the N-terminal region upstream of the EF-hand domain in mouse. UniProtKB:Q3THE2, Thr-19, MOD:00047." [TDR:9744]
comment: Category=organism-modification.
synonym: "mMYL12B/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q3THE2, Thr-19, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:9735
is_a: PR:000010842 ! myosin regulatory light chain 12B
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus