[Term]
id: PR:Q8L7N4
name: E3 ubiquitin-protein ligase SP1 (Arabidopsis thaliana)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]
comment: Category=organism-gene.
synonym: "SP1" RELATED Gene-based [UniProtKB:Q8L7N4]
synonym: "DIAL1" RELATED Gene-based [UniProtKB:Q8L7N4]
synonym: "At-MUL1" EXACT PRO-short-label [PRO:DNx]
synonym: "T12P18.8/T12P18.9" RELATED Gene-based [UniProtKB:Q8L7N4]
synonym: "At1g63900/At1g63890" RELATED Gene-based [UniProtKB:Q8L7N4]
synonym: "DIAP1-like protein 1 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8L7N4]
synonym: "protein SUPPRESSOR OF PPI1 LOCUS 1 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8L7N4]
synonym: "RING-type E3 ubiquitin transferase SP1 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8L7N4]
xref: UniProtKB:Q8L7N4
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000010774 ! mitochondrial ubiquitin ligase activator of NFKB 1
relationship: has_gene_template Araport:AT1G63900 ! SP1 (Arabidopsis thaliana)

[Term]
id: PR:Q969V5
name: mitochondrial ubiquitin ligase activator of NFKB 1 (human)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q969V5]
comment: Category=organism-gene.
synonym: "GIDE" RELATED Gene-based [UniProtKB:Q969V5]
synonym: "MAPL" RELATED Gene-based [UniProtKB:Q969V5]
synonym: "MUL1" RELATED Gene-based [UniProtKB:Q969V5]
synonym: "MULAN" RELATED Gene-based [UniProtKB:Q969V5]
synonym: "hMUL1" EXACT PRO-short-label [PRO:DNx]
synonym: "RNF218" RELATED Gene-based [UniProtKB:Q969V5]
synonym: "C1orf166" RELATED Gene-based [UniProtKB:Q969V5]
synonym: "protein Hades (human)" EXACT [UniProtKB:Q969V5]
synonym: "RING finger protein 218 (human)" EXACT [UniProtKB:Q969V5]
synonym: "E3 SUMO-protein ligase MUL1 (human)" EXACT [UniProtKB:Q969V5]
synonym: "E3 ubiquitin-protein ligase MUL1 (human)" EXACT [UniProtKB:Q969V5]
synonym: "growth inhibition and death E3 ligase (human)" EXACT [UniProtKB:Q969V5]
synonym: "mitochondrial-anchored protein ligase (human)" EXACT [UniProtKB:Q969V5]
synonym: "RING-type E3 ubiquitin transferase NFKB 1 (human)" EXACT [UniProtKB:Q969V5]
synonym: "putative NF-kappa-B-activating protein 266 (human)" EXACT [UniProtKB:Q969V5]
xref: UniProtKB:Q969V5
xref: Reactome:R-HSA-2993772 "PR:Q969V5 located_in GO:0005741"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010774 ! mitochondrial ubiquitin ligase activator of NFKB 1
relationship: has_gene_template HGNC:25762 ! MUL1 (human)

[Term]
id: PR:Q8L7N4-1
name: E3 ubiquitin-protein ligase SP1 isoform 1 (Arabidopsis thaliana)
def: "An E3 ubiquitin-protein ligase SP1 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8L7N4-1." [PRO:DNx, UniProtKB:Q8L7N4]
comment: Category=organism-sequence.
synonym: "At-MUL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8L7N4-1
is_a: PR:Q8L7N4 ! E3 ubiquitin-protein ligase SP1 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:Q8VCM5-1
name: mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1 (mouse)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMUL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8VCM5-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042401 ! mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1

[Term]
id: PR:Q8VCM5-2
name: mitochondrial ubiquitin ligase activator of NFKB 1 isoform m2 (mouse)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VCM5-2." [PRO:DNx, UniProtKB:Q8VCM5]
comment: Category=organism-sequence.
synonym: "mMUL1/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8VCM5-2
is_a: PR:Q8VCM5 ! mitochondrial ubiquitin ligase activator of NFKB 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000010774
name: mitochondrial ubiquitin ligase activator of NFKB 1
def: "A protein that is a translation product of the human MUL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GIDE" RELATED Gene-based []
synonym: "MAPL" RELATED Gene-based []
synonym: "MUL1" EXACT PRO-short-label [PRO:DNx]
synonym: "MULAN" RELATED Gene-based []
synonym: "RNF218" RELATED Gene-based []
synonym: "C1orf166" RELATED Gene-based []
synonym: "protein Hades" EXACT []
synonym: "RING finger protein 218" EXACT []
synonym: "E3 ubiquitin-protein ligase MUL1" EXACT []
synonym: "growth inhibition and death E3 ligase" EXACT []
synonym: "mitochondrial-anchored protein ligase" EXACT []
synonym: "RING-type E3 ubiquitin transferase NFKB 1" EXACT []
synonym: "putative NF-kappa-B-activating protein 266" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8VCM5
name: mitochondrial ubiquitin ligase activator of NFKB 1 (mouse)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 that is encoded in the genome of mouse." [OMA:Q8VCM5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gide" RELATED Gene-based [UniProtKB:Q8VCM5]
synonym: "Mul1" RELATED Gene-based [UniProtKB:Q8VCM5]
synonym: "mMUL1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Hades (mouse)" EXACT [UniProtKB:Q8VCM5]
synonym: "E3 ubiquitin-protein ligase MUL1 (mouse)" EXACT [UniProtKB:Q8VCM5]
synonym: "growth inhibition and death E3 ligase (mouse)" EXACT [UniProtKB:Q8VCM5]
synonym: "RING-type E3 ubiquitin transferase NFKB 1 (mouse)" EXACT [UniProtKB:Q8VCM5]
xref: UniProtKB:Q8VCM5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010774 ! mitochondrial ubiquitin ligase activator of NFKB 1
relationship: has_gene_template MGI:1915600 ! Mul1 (mouse)

[Term]
id: PR:Q8VCM5-3
name: mitochondrial ubiquitin ligase activator of NFKB 1 isoform m3 (mouse)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VCM5-3." [PRO:DNx, UniProtKB:Q8VCM5]
comment: Category=organism-sequence.
synonym: "mMUL1/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8VCM5-3
is_a: PR:Q8VCM5 ! mitochondrial ubiquitin ligase activator of NFKB 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9VZJ9
name: mitochondrial E3 ubiquitin protein ligase 1 (fruit fly)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 that is encoded in the genome of fruit fly." [OMA:Q9VZJ9, PANTHER:PTHR12183:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mul1" RELATED Gene-based [UniProtKB:Q9VZJ9]
synonym: "CG1134" RELATED Gene-based [UniProtKB:Q9VZJ9]
synonym: "fly-MUL1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitochondrial E3 ubiquitin protein transferase 1 (fruit fly)" EXACT [UniProtKB:Q9VZJ9]
xref: UniProtKB:Q9VZJ9
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000010774 ! mitochondrial ubiquitin ligase activator of NFKB 1
relationship: has_gene_template FlyBase:FBgn0035483 ! Mul1 (fruit fly)

[Term]
id: PR:000042401
name: mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q969V5-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "MUL1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010774 ! mitochondrial ubiquitin ligase activator of NFKB 1

[Term]
id: PR:Q969V5-1
name: mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1 (human)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMUL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q969V5-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042401 ! mitochondrial ubiquitin ligase activator of NFKB 1 isoform 1

[Term]
id: PR:000048487
name: mitochondrial ubiquitin ligase activator of NFKB 1 ubiquitinated form (human)
def: "A mitochondrial ubiquitin ligase activator of NFKB 1 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q969V5, MOD:01148." [PRO:DNx, Reactome:R-HSA-6783184]
comment: Category=organism-modification.
synonym: "hMUL1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q969V5, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6783184 "PR:000048487 located_in GO:0005741"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q969V5 ! mitochondrial ubiquitin ligase activator of NFKB 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens