[Term]
id: PR:000048469
name: monofunctional C1-tetrahydrofolate synthase, mitochondrial, transit peptide removed form (human)
def: "A monofunctional C1-tetrahydrofolate synthase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:Q6UB35, 32-978." [PRO:DNx, Reactome:R-HSA-5696852]
comment: Category=organism-modification.
synonym: "PRO_0000343177" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hMTHFD1L/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q6UB35, 32-978" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5696852 "PR:000048469 located_in GO:0005759"
intersection_of: PR:Q6UB35 ! monofunctional C1-tetrahydrofolate synthase, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q6UB35-2
name: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform h2 (human)
def: "A monofunctional C1-tetrahydrofolate synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6UB35-2." [PRO:DNx, UniProtKB:Q6UB35]
comment: Category=organism-sequence.
synonym: "hMTHFD1L/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6UB35-2
is_a: PR:Q6UB35 ! monofunctional C1-tetrahydrofolate synthase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010723
name: monofunctional C1-tetrahydrofolate synthase, mitochondrial
def: "A protein that is a translation product of the human MTHFD1L gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MTHFD1L" EXACT PRO-short-label [PRO:DNx]
synonym: "FTHFSDC1" RELATED Gene-based []
synonym: "formyltetrahydrofolate synthetase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q6UB35
name: monofunctional C1-tetrahydrofolate synthase, mitochondrial (human)
def: "A monofunctional C1-tetrahydrofolate synthase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6UB35]
comment: Category=organism-gene.
synonym: "MTHFD1L" RELATED Gene-based [UniProtKB:Q6UB35]
synonym: "FTHFSDC1" RELATED Gene-based [UniProtKB:Q6UB35]
synonym: "hMTHFD1L" EXACT PRO-short-label [PRO:DNx]
synonym: "formyltetrahydrofolate synthetase (human)" EXACT [UniProtKB:Q6UB35]
xref: UniProtKB:Q6UB35
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010723 ! monofunctional C1-tetrahydrofolate synthase, mitochondrial
relationship: has_gene_template HGNC:21055 ! MTHFD1L (human)

[Term]
id: PR:Q6UB35-1
name: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform h1 (human)
def: "A monofunctional C1-tetrahydrofolate synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6UB35-1." [PRO:DNx, UniProtKB:Q6UB35]
comment: Category=organism-sequence.
synonym: "hMTHFD1L/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6UB35-1
is_a: PR:Q6UB35 ! monofunctional C1-tetrahydrofolate synthase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens