[Term] id: PR:Q13421-1 name: mesothelin isoform h1 (human) def: "A mesothelin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13421-1." [PRO:DNx, UniProtKB:Q13421] comment: Category=organism-sequence. synonym: "hMSLN/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q13421-1 is_a: PR:Q13421 ! mesothelin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13421-2 name: mesothelin isoform h3 (human) def: "A mesothelin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13421-2." [PRO:DNx, UniProtKB:Q13421] comment: Category=organism-sequence. synonym: "hMSLN/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "mesothelin isoform SMRP (human)" EXACT [UniProtKB:Q13421] xref: UniProtKB:Q13421-2 is_a: PR:Q13421 ! mesothelin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13421-3 name: mesothelin isoform h2 (human) def: "A mesothelin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13421-3." [PRO:DNx, UniProtKB:Q13421] comment: Category=organism-sequence. synonym: "hMSLN/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q13421-3 is_a: PR:Q13421 ! mesothelin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13421-4 name: mesothelin isoform h4 (human) def: "A mesothelin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13421-4." [PRO:DNx, UniProtKB:Q13421] comment: Category=organism-sequence. synonym: "hMSLN/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q13421-4 is_a: PR:Q13421 ! mesothelin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13421 name: mesothelin (human) def: "A mesothelin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13421] comment: Category=organism-gene. synonym: "MPF" RELATED Gene-based [UniProtKB:Q13421] synonym: "MSLN" RELATED Gene-based [UniProtKB:Q13421] synonym: "hMSLN" EXACT PRO-short-label [PRO:DNx] synonym: "CAK1 antigen (human)" EXACT [UniProtKB:Q13421] synonym: "pre-pro-megakaryocyte-potentiating factor (human)" EXACT [UniProtKB:Q13421] xref: UniProtKB:Q13421 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000010676 ! mesothelin relationship: has_gene_template HGNC:7371 ! MSLN (human) [Term] id: PR:000020639 name: mesothelin proteolytic cleavage product def: "A mesothelin that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "MSLN/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000010676 ! mesothelin [Term] id: PR:Q61468-1 name: mesothelin isoform 1 (mouse) def: "A mesothelin isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mMSLN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q61468-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000041073 ! mesothelin isoform 1 [Term] id: PR:Q9ERA7 name: mesothelin (rat) def: "A mesothelin that is encoded in the genome of rat." [OMA:Q9ERA7, PANTHER:PTHR23412:SF3, PRO:DNx] comment: Category=organism-gene. synonym: "Erc" RELATED Gene-based [UniProtKB:Q9ERA7] synonym: "Mpf" RELATED Gene-based [UniProtKB:Q9ERA7] synonym: "Msln" RELATED Gene-based [UniProtKB:Q9ERA7] synonym: "rMSLN" EXACT PRO-short-label [PRO:DNx] synonym: "protein expressed in renal carcinoma (rat)" EXACT [UniProtKB:Q9ERA7] synonym: "pre-pro-megakaryocyte-potentiating factor (rat)" EXACT [UniProtKB:Q9ERA7] xref: UniProtKB:Q9ERA7 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000010676 ! mesothelin relationship: has_gene_template RGD:69333 ! Msln (rat) [Term] id: PR:000010676 name: mesothelin def: "A protein that is a translation product of the human MSLN gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MPF" RELATED Gene-based [] synonym: "Mes" RELATED Gene-based [] synonym: "MSLN" EXACT PRO-short-label [PRO:DNx] synonym: "CAK1 antigen" EXACT [] synonym: "pre-pro-megakaryocyte-potentiating factor" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q61468 name: mesothelin (mouse) def: "A mesothelin that is encoded in the genome of mouse." [OMA:Q61468, PRO:DNx] comment: Category=organism-gene. synonym: "Mes" RELATED Gene-based [UniProtKB:Q61468] synonym: "Mpf" RELATED Gene-based [UniProtKB:Q61468] synonym: "Msln" RELATED Gene-based [UniProtKB:Q61468] synonym: "mMSLN" EXACT PRO-short-label [PRO:DNx] synonym: "pre-pro-megakaryocyte-potentiating factor (mouse)" EXACT [UniProtKB:Q61468] xref: UniProtKB:Q61468 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000010676 ! mesothelin relationship: has_gene_template MGI:1888992 ! Msln (mouse) [Term] id: PR:000057022 name: mesothelin N-glycosylated 1 (human) def: "A mesothelin (human) that has been N-glycosylated at the residue equivalent to Asn-496 of the amino acid sequence represented by UniProtKB:Q13421-1, in which the glycan composition is represented by GlyTouCan:G37399XV. Example: UniProtKB:Q13421-1, Asn-496, MOD:00160~GNO:G37399XV." [GlyGen:Q13421-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMSLN/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q13421-1, Asn-496, MOD:00160~GNO:G37399XV" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q13421 ! mesothelin (human) relationship: has_part GNO:G37399XV ! G37399XV relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000020638 name: mesothelin, signal peptide removed form def: "A mesothelin that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "MSLN/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000010676 ! mesothelin intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:Q9ERA7-1 name: mesothelin isoform 1 (rat) def: "A mesothelin isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rMSLN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9ERA7-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000041073 ! mesothelin isoform 1 [Term] id: PR:000041073 name: mesothelin isoform 1 def: "A mesothelin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61468-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "MSLN/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000010676 ! mesothelin