[Term]
id: PR:P08253-1
name: 72 kDa type IV collagenase isoform 1 (human)
def: "A 72 kDa type IV collagenase isoform 1 that is encoded in the genome of human." [PMID:14702039, PMID:2834383, PRO:CNA]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hMMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08253-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037236 ! 72 kDa type IV collagenase isoform 1

[Term]
id: PR:P33436
name: 72 kDa type IV collagenase (rat)
def: "A 72 kDa type IV collagenase that is encoded in the genome of rat." [OMA:P33436, PANTHER:PTHR10201:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mmp2" RELATED Gene-based [UniProtKB:P33436]
synonym: "rMMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "MMP-2 (rat)" EXACT [UniProtKB:P33436]
synonym: "gelatinase A (rat)" EXACT [UniProtKB:P33436]
synonym: "72 kDa gelatinase (rat)" EXACT [UniProtKB:P33436]
synonym: "matrix metalloproteinase-2 (rat)" EXACT [UniProtKB:P33436]
xref: UniProtKB:P33436
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010479 ! 72 kDa type IV collagenase
relationship: has_gene_template RGD:621316 ! Mmp2 (rat)

[Term]
id: PR:Q90611
name: 72 kDa type IV collagenase (chicken)
def: "A 72 kDa type IV collagenase that is encoded in the genome of chicken." [OMA:Q90611, PANTHER:PTHR10201:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "MMP2" RELATED Gene-based [UniProtKB:Q90611]
synonym: "chick-MMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "MMP-2 (chicken)" EXACT [UniProtKB:Q90611]
synonym: "gelatinase A (chicken)" EXACT [UniProtKB:Q90611]
synonym: "72 kDa gelatinase (chicken)" EXACT [UniProtKB:Q90611]
synonym: "matrix metalloproteinase-2 (chicken)" EXACT [UniProtKB:Q90611]
xref: UniProtKB:Q90611
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000010479 ! 72 kDa type IV collagenase
relationship: has_gene_template NCBIGene:386583 ! MMP2 (chicken)

[Term]
id: PR:P33434
name: 72 kDa type IV collagenase (mouse)
def: "A 72 kDa type IV collagenase that is encoded in the genome of mouse." [OMA:P33434, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mmp2" RELATED Gene-based [UniProtKB:P33434]
synonym: "mMMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "MMP-2 (mouse)" EXACT [UniProtKB:P33434]
synonym: "gelatinase A (mouse)" EXACT [UniProtKB:P33434]
synonym: "72 kDa gelatinase (mouse)" EXACT [UniProtKB:P33434]
synonym: "matrix metalloproteinase-2 (mouse)" EXACT [UniProtKB:P33434]
xref: UniProtKB:P33434
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010479 ! 72 kDa type IV collagenase
relationship: has_gene_template MGI:97009 ! Mmp2 (mouse)

[Term]
id: PR:000054441
name: 72 kDa type IV collagenase O-glycosylated 1 (human)
def: "A 72 kDa type IV collagenase (human) that has been O-glycosylated at the residue equivalent to Thr-460 of the amino acid sequence represented by UniProtKB:P08253-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P08253-1, Thr-460, MOD:00005~GNO:G29068FM." [GlyGen:P08253-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hMMP2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08253-1, Thr-460, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08253 ! 72 kDa type IV collagenase (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054442
name: 72 kDa type IV collagenase O-glycosylated 2 (human)
def: "A 72 kDa type IV collagenase (human) that has been O-glycosylated at the residue equivalent to Thr-460 of the amino acid sequence represented by UniProtKB:P08253-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08253-1, Thr-460, MOD:00005~GNO:G43417UB." [GlyGen:P08253-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hMMP2/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08253-1, Thr-460, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08253 ! 72 kDa type IV collagenase (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P33434-2
name: 72 kDa type IV collagenase isoform 2 (mouse)
def: "A 72 kDa type IV collagenase isoform 2 that is encoded in the genome of mouse." [PMID:22509276, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mMMP2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P33434-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037238 ! 72 kDa type IV collagenase isoform 2

[Term]
id: PR:000048400
name: 72 kDa type IV collagenase, signal peptide removed form (human)
def: "A 72 kDa type IV collagenase (human) that has had the signal peptide removed. UniProtKB:P08253, 30-660." [PRO:DNx, Reactome:R-HSA-1604364]
comment: Category=organism-modification.
synonym: "hMMP2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08253, 30-660" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1604364 "PR:000048400 located_in GO:0005576"
intersection_of: PR:P08253 ! 72 kDa type IV collagenase (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010479
name: 72 kDa type IV collagenase
def: "A protein that is a translation product of the human MMP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "CLG4A" RELATED Gene-based []
synonym: "MMP-2" EXACT []
synonym: "TBE-1" EXACT []
synonym: "gelatinase A" EXACT []
synonym: "72 kDa gelatinase" EXACT []
synonym: "matrix metalloproteinase-2" EXACT []
xref: IUPHARobj:1629
is_a: PR:000000001 ! protein

[Term]
id: PR:P08253-2
name: 72 kDa type IV collagenase isoform 2 (human)
def: "A 72 kDa type IV collagenase isoform 2 that is encoded in the genome of human." [PMID:14702039, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hMMP2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08253-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037238 ! 72 kDa type IV collagenase isoform 2

[Term]
id: PR:P08253-3
name: 72 kDa type IV collagenase isoform h3 (human)
def: "A 72 kDa type IV collagenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08253-3." [PRO:DNx, UniProtKB:P08253]
comment: Category=organism-sequence.
synonym: "hMMP2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08253-3
is_a: PR:P08253 ! 72 kDa type IV collagenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037236
name: 72 kDa type IV collagenase isoform 1
def: "A 72 kDa type IV collagenase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33434-1 or a 1:1 ortholog thereof." [PMID:1373140, PRO:HJD]
comment: Category=sequence.
synonym: "MMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010479 ! 72 kDa type IV collagenase

[Term]
id: PR:000037238
name: 72 kDa type IV collagenase isoform 2
def: "A 72 kDa type IV collagenase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33434-2 or a 1:1 ortholog thereof. This form lacks the region that codes for the N-terminal signal peptide and part of the propeptide." [PMID:22509276, PRO:HJD]
comment: Category=sequence.
synonym: "MMP2/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010479 ! 72 kDa type IV collagenase

[Term]
id: PR:P33434-1
name: 72 kDa type IV collagenase isoform 1 (mouse)
def: "A 72 kDa type IV collagenase isoform 1 that is encoded in the genome of mouse." [PMID:1373140, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mMMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P33434-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037236 ! 72 kDa type IV collagenase isoform 1

[Term]
id: PR:P08253
name: 72 kDa type IV collagenase (human)
def: "A 72 kDa type IV collagenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08253]
comment: Category=organism-gene.
synonym: "MMP2" RELATED Gene-based [UniProtKB:P08253]
synonym: "CLG4A" RELATED Gene-based [UniProtKB:P08253]
synonym: "hMMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "MMP-2 (human)" EXACT [UniProtKB:P08253]
synonym: "TBE-1 (human)" EXACT [UniProtKB:P08253]
synonym: "gelatinase A (human)" EXACT [UniProtKB:P08253]
synonym: "72 kDa gelatinase (human)" EXACT [UniProtKB:P08253]
synonym: "matrix metalloproteinase-2 (human)" EXACT [UniProtKB:P08253]
xref: UniProtKB:P08253
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010479 ! 72 kDa type IV collagenase
relationship: has_gene_template HGNC:7166 ! MMP2 (human)

[Term]
id: PR:000020610
name: 72 kDa type IV collagenase proteolytic cleavage product
def: "A 72 kDa type IV collagenase that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "MMP2/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000010479 ! 72 kDa type IV collagenase