[Term]
id: PR:P49735
name: DNA replication licensing factor Mcm2 (fruit fly)
def: "A DNA replication licensing factor MCM2 that is encoded in the genome of fruit fly." [OMA:P49735, PANTHER:PTHR11630:SF44, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mcm2" RELATED Gene-based [UniProtKB:P49735]
synonym: "CG7538" RELATED Gene-based [UniProtKB:P49735]
synonym: "DmMCM2" EXACT [UniProtKB:P49735]
synonym: "fly-MCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "minichromosome maintenance 2 protein (fruit fly)" EXACT [UniProtKB:P49735]
xref: UniProtKB:P49735
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
relationship: has_gene_template FlyBase:FBgn0014861 ! Mcm2 (fruit fly)

[Term]
id: PR:P49736
name: DNA replication licensing factor MCM2 (human)
def: "A DNA replication licensing factor MCM2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49736]
comment: Category=organism-gene.
synonym: "BM28" RELATED Gene-based [UniProtKB:P49736]
synonym: "MCM2" RELATED Gene-based [UniProtKB:P49736]
synonym: "CCNL1" RELATED Gene-based [UniProtKB:P49736]
synonym: "CDCL1" RELATED Gene-based [UniProtKB:P49736]
synonym: "hMCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0030" RELATED Gene-based [UniProtKB:P49736]
synonym: "nuclear protein BM28 (human)" EXACT [UniProtKB:P49736]
synonym: "minichromosome maintenance protein 2 homolog (human)" EXACT [UniProtKB:P49736]
xref: UniProtKB:P49736
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
relationship: has_gene_template HGNC:6944 ! MCM2 (human)

[Term]
id: PR:P97310
name: DNA replication licensing factor MCM2 (mouse)
def: "A DNA replication licensing factor MCM2 that is encoded in the genome of mouse." [OMA:P97310, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bm28" RELATED Gene-based [UniProtKB:P97310]
synonym: "Mcm2" RELATED Gene-based [UniProtKB:P97310]
synonym: "Cdcl1" RELATED Gene-based [UniProtKB:P97310]
synonym: "Mcmd2" RELATED Gene-based [UniProtKB:P97310]
synonym: "mMCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa0030" RELATED Gene-based [UniProtKB:P97310]
synonym: "nuclear protein BM28 (mouse)" EXACT [UniProtKB:P97310]
synonym: "minichromosome maintenance protein 2 homolog (mouse)" EXACT [UniProtKB:P97310]
xref: UniProtKB:P97310
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
relationship: has_gene_template MGI:105380 ! Mcm2 (mouse)

[Term]
id: PR:000039599
name: DNA replication licensing factor MCM2 isoform 1
def: "A DNA replication licensing factor MCM2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49736-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "MCM2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010242 ! DNA replication licensing factor MCM2

[Term]
id: PR:P40377
name: DNA replication licensing factor mcm2 (Schizosaccharomyces pombe 972h-)
def: "A DNA replication licensing factor MCM2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P40377, PANTHER:PTHR11630:SF44, PRO:DNx]
comment: Category=organism-gene.
synonym: "mcm2" RELATED Gene-based [UniProtKB:P40377]
synonym: "nda1" RELATED Gene-based [UniProtKB:P40377]
synonym: "cdc19" RELATED Gene-based [UniProtKB:P40377]
synonym: "SPBC4.04c" RELATED Gene-based [UniProtKB:P40377]
synonym: "Spom972h-MCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division control protein 19 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P40377]
synonym: "minichromosome maintenance protein 2 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P40377]
xref: UniProtKB:P40377
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
relationship: has_gene_template PomBase:SPBC4.04c ! mcm2 (Schizosaccharomyces pombe)

[Term]
id: PR:Q9LPD9
name: DNA replication licensing factor MCM2 (Arabidopsis thaliana)
def: "A DNA replication licensing factor MCM2 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9LPD9, PANTHER:PTHR11630:SF44, PRO:DNx]
comment: Category=organism-gene.
synonym: "MCM2" RELATED Gene-based [UniProtKB:Q9LPD9]
synonym: "AtMCM2" EXACT [UniProtKB:Q9LPD9]
synonym: "At-MCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "At1g44900" RELATED Gene-based [UniProtKB:Q9LPD9]
synonym: "T12C22.19" RELATED Gene-based [UniProtKB:Q9LPD9]
synonym: "minichromosome maintenance protein 2 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9LPD9]
xref: UniProtKB:Q9LPD9
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
relationship: has_gene_template Araport:AT1G44900 ! MCM2 (Arabidopsis thaliana)

[Term]
id: PR:000020558
name: DNA replication licensing factor MCM2, initiator methionine removed form
def: "A DNA replication licensing factor MCM2 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "MCM2/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q9LPD9-1
name: DNA replication licensing factor MCM2 isoform 1 (Arabidopsis thaliana)
def: "A DNA replication licensing factor MCM2 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9LPD9-1." [PRO:DNx, UniProtKB:Q9LPD9]
comment: Category=organism-sequence.
synonym: "At-MCM2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9LPD9-1
is_a: PR:Q9LPD9 ! DNA replication licensing factor MCM2 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:P29469
name: DNA replication licensing factor MCM2 (yeast)
def: "A DNA replication licensing factor MCM2 that is encoded in the genome of yeast." [OMA:P29469, PANTHER:PTHR11630:SF44, PRO:DNx]
comment: Category=organism-gene.
synonym: "MCM2" RELATED Gene-based [UniProtKB:P29469]
synonym: "yMCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "YBL023C" RELATED Gene-based [UniProtKB:P29469]
synonym: "YBL0438" RELATED Gene-based [UniProtKB:P29469]
synonym: "minichromosome maintenance protein 2 (yeast)" EXACT [UniProtKB:P29469]
xref: UniProtKB:P29469
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000010242 ! DNA replication licensing factor MCM2
relationship: has_gene_template SGD:S000000119 ! MCM2 (yeast)

[Term]
id: PR:000010242
name: DNA replication licensing factor MCM2
def: "A protein that is a translation product of the human MCM2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BM28" RELATED Gene-based []
synonym: "MCM2" EXACT PRO-short-label [PRO:DNx]
synonym: "CCNL1" RELATED Gene-based []
synonym: "CDCL1" RELATED Gene-based []
synonym: "Mcmd2" RELATED Gene-based []
synonym: "KIAA0030" RELATED Gene-based []
synonym: "nuclear protein BM28" EXACT []
synonym: "minichromosome maintenance protein 2 homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000026396
name: DNA replication licensing factor MCM2, initiator methionine removed form (human)
def: "A DNA replication licensing factor MCM2, initiator methionine removed form in human. UniProtKB:P49736, 2-904." [PRO:DNx]
comment: Category=organism-modification.
synonym: "PRO_0000194087" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hMCM2/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49736, 2-904" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-68557 "PR:000026396 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000020558 ! DNA replication licensing factor MCM2, initiator methionine removed form

[Term]
id: PR:000045804
name: DNA replication licensing factor MCM2 phosphorylated 1 (human)
def: "A DNA replication licensing factor MCM2 (human) that has been phosphorylated at Ser-108. UniProtKB:P49736, Ser-108, MOD:00046." [PMID:15210935, iPTMnet:P49736]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15210935). Status=unreviewed.
synonym: "hMCM2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49736, Ser-108, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P49736 ! DNA replication licensing factor MCM2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P97310-1
name: DNA replication licensing factor MCM2 isoform 1 (mouse)
def: "A DNA replication licensing factor MCM2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMCM2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97310-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039599 ! DNA replication licensing factor MCM2 isoform 1

[Term]
id: PR:P49736-1
name: DNA replication licensing factor MCM2 isoform 1 (human)
def: "A DNA replication licensing factor MCM2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMCM2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49736-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039599 ! DNA replication licensing factor MCM2 isoform 1