[Term]
id: PR:000026224
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 that has been processed by proteolytic cleavage to remove the N-terminal portion that serves as both mitochondrial targeting and processing signal. Example: UniProtKB:P97287-1, 34-331." [PMID:20627101, PRO:HJD]
comment: Category=modification.
synonym: "MCL1/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026005 ! induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1

[Term]
id: PR:000026225
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 in mouse. It lacks the N-terminal portion encompassing 33 amino acids. This form is generated by cleavage within the mitochondrial matrix. UniProtKB:P97287-1, 34-331." [PMID:20627101, PRO:HJD]
comment: Category=organism-modification.
synonym: "mMCL1/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P97287-1, 34-331" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026224 ! induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1

[Term]
id: PR:Q9Z1P3
name: induced myeloid leukemia cell differentiation protein Mcl-1 homolog (rat)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of rat." [PANTHER:PTHR11256:SF6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mcl1" RELATED Gene-based [UniProtKB:Q9Z1P3]
synonym: "rMCL1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z1P3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010240 ! induced myeloid leukemia cell differentiation protein Mcl-1
relationship: has_gene_template RGD:620525 ! Mcl1 (rat)

[Term]
id: PR:000010240
name: induced myeloid leukemia cell differentiation protein Mcl-1
def: "A protein that is a translation product of the human MCL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MCL1" EXACT PRO-short-label [PRO:DNx]
synonym: "BCL2L3" RELATED Gene-based []
synonym: "Bcl2-L-3" EXACT []
synonym: "mcl1/EAT" EXACT []
synonym: "Bcl-2-like protein 3" EXACT []
synonym: "Bcl-2-related protein EAT/mcl1" EXACT []
xref: IUPHARobj:2847
is_a: PR:000000001 ! protein

[Term]
id: PR:P97287
name: induced myeloid leukemia cell differentiation protein Mcl-1 homolog (mouse)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of mouse." [OMA:P97287, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mcl1" RELATED Gene-based [UniProtKB:P97287]
synonym: "mMCL1" EXACT PRO-short-label [PRO:DNx]
synonym: "Bcl-2-related protein EAT/mcl1 (mouse)" EXACT [UniProtKB:P97287]
xref: UniProtKB:P97287
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010240 ! induced myeloid leukemia cell differentiation protein Mcl-1
relationship: has_gene_template MGI:101769 ! Mcl1 (mouse)

[Term]
id: PR:Q07820-1
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform h1 (human)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07820-1." [PRO:DNx, UniProtKB:Q07820]
comment: Category=organism-sequence.
synonym: "hMCL1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "induced myeloid leukemia cell differentiation protein Mcl-1 isoform MCL1L (human)" EXACT [UniProtKB:Q07820]
synonym: "induced myeloid leukemia cell differentiation protein Mcl-1 isoform MCL-1L (human)" EXACT [UniProtKB:Q07820]
xref: UniProtKB:Q07820-1
is_a: PR:Q07820 ! induced myeloid leukemia cell differentiation protein Mcl-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q07820-2
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform h2 (human)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07820-2." [PRO:DNx, UniProtKB:Q07820]
comment: Category=organism-sequence.
synonym: "hMCL1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "induced myeloid leukemia cell differentiation protein Mcl-1 isoform TM (human)" EXACT [UniProtKB:Q07820]
synonym: "induced myeloid leukemia cell differentiation protein Mcl-1 isoform MCL-1S (human)" EXACT [UniProtKB:Q07820]
synonym: "induced myeloid leukemia cell differentiation protein Mcl-1 isoform Delta S (human)" EXACT [UniProtKB:Q07820]
xref: UniProtKB:Q07820-2
is_a: PR:Q07820 ! induced myeloid leukemia cell differentiation protein Mcl-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000026005
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97287-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "MCL1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010240 ! induced myeloid leukemia cell differentiation protein Mcl-1

[Term]
id: PR:000026007
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97287-2 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "MCL1/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010240 ! induced myeloid leukemia cell differentiation protein Mcl-1

[Term]
id: PR:Q07820
name: induced myeloid leukemia cell differentiation protein Mcl-1 (human)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q07820]
comment: Category=organism-gene.
synonym: "MCL1" RELATED Gene-based [UniProtKB:Q07820]
synonym: "hMCL1" EXACT PRO-short-label [PRO:DNx]
synonym: "BCL2L3" RELATED Gene-based [UniProtKB:Q07820]
synonym: "Bcl2-L-3 (human)" EXACT [UniProtKB:Q07820]
synonym: "mcl1/EAT (human)" EXACT [UniProtKB:Q07820]
synonym: "Bcl-2-like protein 3 (human)" EXACT [UniProtKB:Q07820]
synonym: "Bcl-2-related protein EAT/mcl1 (human)" EXACT [UniProtKB:Q07820]
xref: Reactome:R-HSA-5661490 "PR:Q07820 located_in GO:0005829"
xref: UniProtKB:Q07820
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010240 ! induced myeloid leukemia cell differentiation protein Mcl-1
relationship: has_gene_template HGNC:6943 ! MCL1 (human)

[Term]
id: PR:P97287-1
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 that is encoded in the genome of mouse." [PMID:9655929, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mMCL1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "MCL-1L (mouse)" EXACT []
xref: UniProtKB:P97287-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026005 ! induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1

[Term]
id: PR:P97287-2
name: induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 (mouse)
def: "An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 that is encoded in the genome of mouse." [PMID:19919825, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mMCL1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "MCL-1V (mouse)" EXACT []
xref: UniProtKB:P97287-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026007 ! induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2