[Term]
id: PR:O43462
name: membrane-bound transcription factor site-2 protease (human)
def: "A membrane-bound transcription factor site-2 protease that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43462]
comment: Category=organism-gene.
synonym: "S2P" RELATED Gene-based [UniProtKB:O43462]
synonym: "MBTPS2" RELATED Gene-based [UniProtKB:O43462]
synonym: "hMBTPS2" EXACT PRO-short-label [PRO:DNx]
synonym: "endopeptidase S2P (human)" EXACT [UniProtKB:O43462]
synonym: "SREBPs intramembrane protease (human)" EXACT [UniProtKB:O43462]
synonym: "sterol regulatory element-binding proteins intramembrane protease (human)" EXACT [UniProtKB:O43462]
xref: Reactome:R-HSA-381131 "PR:O43462 located_in GO:0000139"
xref: Reactome:R-HSA-6784617 "PR:O43462 located_in GO:0005789"
xref: UniProtKB:O43462
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010230 ! membrane-bound transcription factor site-2 protease
relationship: has_gene_template HGNC:15455 ! MBTPS2 (human)

[Term]
id: PR:000010230
name: membrane-bound transcription factor site-2 protease
def: "A protein that is a translation product of the human MBTPS2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "S2P" RELATED Gene-based []
synonym: "MBTPS2" EXACT PRO-short-label [PRO:DNx]
synonym: "endopeptidase S2P" EXACT []
synonym: "SREBPs intramembrane protease" EXACT []
synonym: "sterol regulatory element-binding proteins intramembrane protease" EXACT []
is_a: PR:000000001 ! protein