[Term]
id: PR:O43462
name: membrane-bound transcription factor site-2 protease (human)
def: "A membrane-bound transcription factor site-2 protease that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43462]
comment: Category=organism-gene.
synonym: "S2P" RELATED Gene-based [UniProtKB:O43462]
synonym: "MBTPS2" RELATED Gene-based [UniProtKB:O43462]
synonym: "hMBTPS2" EXACT PRO-short-label [PRO:DNx]
synonym: "endopeptidase S2P (human)" EXACT [UniProtKB:O43462]
synonym: "SREBPs intramembrane protease (human)" EXACT [UniProtKB:O43462]
synonym: "sterol regulatory element-binding proteins intramembrane protease (human)" EXACT [UniProtKB:O43462]
xref: Reactome:R-HSA-381131 "PR:O43462 located_in GO:0000139"
xref: Reactome:R-HSA-6784617 "PR:O43462 located_in GO:0005789"
xref: UniProtKB:O43462
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010230 ! membrane-bound transcription factor site-2 protease
relationship: has_gene_template HGNC:15455 ! MBTPS2 (human)

[Term]
id: PR:F4JUU5-1
name: membrane-bound transcription factor site-2 protease homolog isoform 1 (Arabidopsis thaliana)
def: "A membrane-bound transcription factor site-2 protease homolog (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F4JUU5-1." [PRO:DNx, UniProtKB:F4JUU5]
comment: Category=organism-sequence.
synonym: "At-MBTPS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:F4JUU5-1
is_a: PR:F4JUU5 ! membrane-bound transcription factor site-2 protease homolog (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:F4JUU5
name: membrane-bound transcription factor site-2 protease homolog (Arabidopsis thaliana)
def: "A membrane-bound transcription factor site-2 protease that is encoded in the genome of Arabidopsis thaliana." [OMA:F4JUU5, PANTHER:PTHR13325:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "S2P" RELATED Gene-based [UniProtKB:F4JUU5]
synonym: "At-MBTPS2" EXACT PRO-short-label [PRO:DNx]
synonym: "At4g20310" RELATED Gene-based [UniProtKB:F4JUU5]
synonym: "F1C12.220" RELATED Gene-based [UniProtKB:F4JUU5]
synonym: "endopeptidase S2P (Arabidopsis thaliana)" EXACT [UniProtKB:F4JUU5]
xref: UniProtKB:F4JUU5
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000010230 ! membrane-bound transcription factor site-2 protease
relationship: has_gene_template Araport:AT4G20310 ! S2P (Arabidopsis thaliana)

[Term]
id: PR:000010230
name: membrane-bound transcription factor site-2 protease
def: "A protein that is a translation product of the human MBTPS2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "S2P" RELATED Gene-based []
synonym: "MBTPS2" EXACT PRO-short-label [PRO:DNx]
synonym: "endopeptidase S2P" EXACT []
synonym: "SREBPs intramembrane protease" EXACT []
synonym: "sterol regulatory element-binding proteins intramembrane protease" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8CHX6
name: membrane-bound transcription factor site-2 protease (mouse)
def: "A membrane-bound transcription factor site-2 protease that is encoded in the genome of mouse." [OMA:Q8CHX6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mbtps2" RELATED Gene-based [UniProtKB:Q8CHX6]
synonym: "mMBTPS2" EXACT PRO-short-label [PRO:DNx]
synonym: "endopeptidase S2P (mouse)" EXACT [UniProtKB:Q8CHX6]
xref: UniProtKB:Q8CHX6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010230 ! membrane-bound transcription factor site-2 protease
relationship: has_gene_template MGI:2444506 ! Mbtps2 (mouse)