[Term]
id: PR:G5EEH5
name: max-like protein 1 (worm)
def: "A protein max that is encoded in the genome of worm." [OMA:G5EEH5, PRO:DNx]
comment: Category=organism-gene.
synonym: "mxl-1" RELATED Gene-based [UniProtKB:G5EEH5]
synonym: "T19B10.11" RELATED Gene-based [UniProtKB:G5EEH5]
synonym: "MAX (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:G5EEH5
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template WormBase:WBGene00003509 ! mxl-1 (worm)

[Term]
id: PR:000025920
name: protein max isoform short acetylated 1
def: "A protein max isoform short that has been acetylated by the histone acetyltransferase p300. Example: UniProtKB:P61244-2, Lys-57/Lys-144/Lys-145, MOD:00064." [PMID:17217336, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "MAX/iso:short/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025914 ! protein max isoform short
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000025921
name: protein max isoform short acetylated 1 (human)
def: "A protein max isoform short acetylated 1 in human. UniProtKB:P61244-2, Lys-57/Lys-144/Lys-145, MOD:00064." [PMID:17217336, PRO:CNA]
comment: Category=organism-modification.
synonym: "hMAX/iso:short/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P61244-2, Lys-57/Lys-144/Lys-145, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025920 ! protein max isoform short acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:P52161-1
name: protein max isoform Long (zebrafish)
def: "A protein max (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52161-1." [PRO:DNx, UniProtKB:P52161]
comment: Category=organism-sequence.
synonym: "z-MAX/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52161-1
is_a: PR:P52161 ! protein max (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:P52161-2
name: protein max isoform Short (zebrafish)
def: "A protein max (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52161-2." [PRO:DNx, UniProtKB:P52161]
comment: Category=organism-sequence.
synonym: "z-MAX/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52161-2
is_a: PR:P52161 ! protein max (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:000026037
name: protein max isoform short unmodified form (human)
def: "A protein max isoform short unmodified form in human." [PMID:15003254, PRO:CNA]
comment: Category=organism-modification.
synonym: "hMAX/iso:short/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025915 ! protein max isoform short unmodified form

[Term]
id: PR:P52162-2
name: protein max isoform Short (chicken)
def: "A protein max (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52162-2." [PRO:DNx, UniProtKB:P52162]
comment: Category=organism-sequence.
synonym: "chick-MAX/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52162-2
is_a: PR:P52162 ! protein max (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:P52162-1
name: protein max isoform Long (chicken)
def: "A protein max (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52162-1." [PRO:DNx, UniProtKB:P52162]
comment: Category=organism-sequence.
synonym: "chick-MAX/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52162-1
is_a: PR:P52162 ! protein max (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:000048347
name: protein max, initiator methionine removed form (human)
def: "A protein max (human) that has had the initiator methionine removed. UniProtKB:P61244, 2-160." [PRO:DNx, Reactome:R-HSA-3006627]
comment: Category=organism-modification.
synonym: "hMAX/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000127269" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P61244, 2-160" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3006627 "PR:000048347 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P61244 ! protein max (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P28574
name: protein max (mouse)
def: "A protein max that is encoded in the genome of mouse." [OMA:P28574, PRO:CNA]
comment: Category=organism-gene.
synonym: "Max" RELATED Gene-based [UniProtKB:P28574]
synonym: "Myn" RELATED Gene-based [UniProtKB:P28574]
synonym: "mMAX" EXACT PRO-short-label [PRO:DNx]
synonym: "protein myn (mouse)" EXACT [UniProtKB:P28574]
synonym: "Myc-associated factor X (mouse)" EXACT [UniProtKB:P28574]
synonym: "Myc-binding novel HLH/LZ protein (mouse)" EXACT [UniProtKB:P28574]
xref: UniProtKB:P28574
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template MGI:96921 ! Max (mouse)

[Term]
id: PR:P91664
name: protein max (fruit fly)
def: "A protein max that is encoded in the genome of fruit fly." [OMA:P91664, PANTHER:PTHR10328:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Max" RELATED Gene-based [UniProtKB:P91664]
synonym: "dMax" EXACT [UniProtKB:P91664]
synonym: "CG9648" RELATED Gene-based [UniProtKB:P91664]
synonym: "fly-MAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Myc-associated factor X (fruit fly)" EXACT [UniProtKB:P91664]
xref: UniProtKB:P91664
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template FlyBase:FBgn0017578 ! Max (fruit fly)

[Term]
id: PR:P28574-2
name: protein max isoform short (mouse)
def: "A protein max isoform short that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mMAX/iso:short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28574-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025914 ! protein max isoform short

[Term]
id: PR:P28574-1
name: protein max isoform 1 (mouse)
def: "A protein max isoform long that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mMAX/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28574-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025911 ! protein max isoform long

[Term]
id: PR:000010211
name: protein max
def: "A protein that is a translation product of the human MAX gene or a 1:1 ortholog thereof. Max belongs to the clade B of the bHLH proteins (see PMID:20219281). The prototypical protein contains a Helix-loop-helix DNA-binding domain (Pfam:PF00010)." [PMID:20219281, PRO:CNA]
comment: Category=gene.
synonym: "MAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Myn" RELATED Gene-based []
synonym: "BHLHD4" RELATED Gene-based []
synonym: "bHLHd4" EXACT []
synonym: "protein myn" EXACT []
synonym: "bHLH clade B" BROAD [PMID:20219281]
synonym: "Myc-associated factor X" EXACT []
synonym: "Myc-binding novel HLH/LZ protein" EXACT []
synonym: "class D basic helix-loop-helix protein 4" EXACT []
xref: PIRSF:PIRSF038026
is_a: PR:000000001 ! protein

[Term]
id: PR:P61244
name: protein max (human)
def: "A protein max that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-gene.
synonym: "MAX" RELATED Gene-based [UniProtKB:P61244]
synonym: "hMAX" EXACT PRO-short-label [PRO:DNx]
synonym: "BHLHD4" RELATED Gene-based [UniProtKB:P61244]
synonym: "Myc-associated factor X (human)" EXACT [UniProtKB:P61244]
synonym: "class D basic helix-loop-helix protein 4 (human)" EXACT [UniProtKB:P61244]
xref: UniProtKB:P61244
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template HGNC:6913 ! MAX (human)

[Term]
id: PR:000025913
name: protein max isoform long phosphorylated 1
def: "A protein max isoform long that has been phosphorylated at two Ser residues in the N-terminal region. Example: UniProtKB:P61244-1, Ser-2/Ser-11, MOD:00046." [PMID:8018564, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "MAX/iso:long/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025911 ! protein max isoform long
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000025912
name: protein max isoform long unmodified form
def: "A protein max isoform long that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PMID:8018564, PRO:CNA]
comment: Category=modification.
synonym: "MAX/iso:long/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part PR:000021935 ! immature protein part
intersection_of: lacks_part PR:000025513 ! modified amino-acid residue
intersection_of: PR:000025911 ! protein max isoform long
disjoint_from: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000025911
name: protein max isoform long
def: "A protein max that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-1 or a 1:1 ortholog thereof." [PMID:8018564, PRO:CNA]
comment: Category=sequence.
synonym: "p22max" EXACT []
synonym: "MAX/iso:long" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010211 ! protein max

[Term]
id: PR:000025917
name: protein max isoform long phosphorylated 1 (human)
def: "A protein max isoform long phosphorylated 1 in human. UniProtKB:P61244-1, Ser-2/Ser-11, MOD:00046." [PMID:8018564, PRO:CNA, PhosphoSitePlus:2689]
comment: Category=organism-modification.
synonym: "hMAX/iso:long/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P61244-1, Ser-2/Ser-11, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025913 ! protein max isoform long phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000025916
name: protein max isoform short phosphorylated 1
def: "A protein max isoform short that has been phosphorylated at two Ser residues in the N-terminal CKII sites. Example: UniProtKB:P61244-2, Ser-2/Ser-11, MOD:00046." [PMID:8018564, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "MAX/iso:short/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p21max phosphorylated" EXACT []
is_a: PR:000025914 ! protein max isoform short
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000025915
name: protein max isoform short unmodified form
def: "A protein max isoform short that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PMID:8018564, PRO:CNA]
comment: Category=modification.
synonym: "MAX/iso:short/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part PR:000021935 ! immature protein part
intersection_of: lacks_part PR:000025513 ! modified amino-acid residue
intersection_of: PR:000025914 ! protein max isoform short
disjoint_from: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000025914
name: protein max isoform short
def: "A protein max that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-2 or a 1:1 ortholog thereof." [PMID:8018564, PRO:CNA]
comment: Category=sequence.
synonym: "p21max" EXACT []
synonym: "MAX/iso:short" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010211 ! protein max

[Term]
id: PR:P61244-3
name: protein max isoform 3 (human)
def: "A protein max isoform delta-max that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hMAX/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Max isoform Delta-Max (human)" EXACT [UniProtKB:P61244]
xref: UniProtKB:P61244-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025919 ! protein max isoform delta-max

[Term]
id: PR:P61244-2
name: protein max isoform short (human)
def: "A protein max isoform short that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hMAX/iso:short" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Max isoform 2 (human)" EXACT [UniProtKB:P61244]
xref: UniProtKB:P61244-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025914 ! protein max isoform short

[Term]
id: PR:000025919
name: protein max isoform delta-max
def: "A protein max that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-3 or a 1:1 ortholog thereof." [PMID:1566084, PRO:CNA]
comment: Category=sequence.
synonym: "MAX/iso:delta-max" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010211 ! protein max

[Term]
id: PR:000025918
name: protein max isoform short phosphorylated 1 (human)
def: "A protein max isoform short phosphorylated 1 in human. UniProtKB:P61244-2, Ser-2/Ser-11, MOD:00046." [PMID:8018564, PRO:CNA, PhosphoSitePlus:2689]
comment: Category=organism-modification.
synonym: "hMAX/iso:short/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P61244-2, Ser-2/Ser-11, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025916 ! protein max isoform short phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:P61244-6
name: protein max isoform h6 (human)
def: "A protein max (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-6." [PRO:DNx, UniProtKB:P61244]
comment: Category=organism-sequence.
synonym: "hMAX/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61244-6
is_a: PR:P61244 ! protein max (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P61244-5
name: protein max isoform h5 (human)
def: "A protein max (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-5." [PRO:DNx, UniProtKB:P61244]
comment: Category=organism-sequence.
synonym: "hMAX/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61244-5
is_a: PR:P61244 ! protein max (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P61244-4
name: protein max isoform h4 (human)
def: "A protein max (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-4." [PRO:DNx, UniProtKB:P61244]
comment: Category=organism-sequence.
synonym: "hMAX/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61244-4
is_a: PR:P61244 ! protein max (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P52161
name: protein max (zebrafish)
def: "A protein max that is encoded in the genome of zebrafish." [PANTHER:PTHR10328:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "max" RELATED Gene-based [UniProtKB:P52161]
synonym: "z-MAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Myc-associated factor X (zebrafish)" EXACT [UniProtKB:P52161]
xref: UniProtKB:P52161
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template ZFIN:ZDB-GENE-990415-152 ! max (zebrafish)

[Term]
id: PR:P52164-1
name: protein max isoform Long (rat)
def: "A protein max isoform long that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "rMAX/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52164-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000025911 ! protein max isoform long

[Term]
id: PR:P52164-2
name: protein max isoform Short (rat)
def: "A protein max isoform short that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "rMAX/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52164-2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000025914 ! protein max isoform short

[Term]
id: PR:P52162
name: protein max (chicken)
def: "A protein max that is encoded in the genome of chicken." [OMA:P52162, PRO:DNx]
comment: Category=organism-gene.
synonym: "MAX" RELATED Gene-based [UniProtKB:P52162]
synonym: "chick-MAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Myc-associated factor X (chicken)" EXACT [UniProtKB:P52162]
xref: UniProtKB:P52162
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template NCBIGene:100858676 ! MAX (chicken)

[Term]
id: PR:P52164
name: protein max (rat)
def: "A protein max that is encoded in the genome of rat." [OMA:P52164, PRO:DNx]
comment: Category=organism-gene.
synonym: "Max" RELATED Gene-based [UniProtKB:P52164]
synonym: "rMAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Myc-associated factor X (rat)" EXACT [UniProtKB:P52164]
xref: UniProtKB:P52164
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010211 ! protein max
relationship: has_gene_template RGD:621101 ! Max (rat)

[Term]
id: PR:P61244-1
name: protein max isoform long (human)
def: "A protein max isoform long that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hMAX/iso:long" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Max isoform 1 (human)" EXACT [UniProtKB:P61244]
xref: UniProtKB:P61244-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025911 ! protein max isoform long