[Term]
id: PR:Q7Z434
name: mitochondrial antiviral-signaling protein (human)
def: "A mitochondrial antiviral-signaling protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-gene.
synonym: "IPS1" RELATED Gene-based [UniProtKB:Q7Z434]
synonym: "MAVS" RELATED Gene-based [UniProtKB:Q7Z434]
synonym: "VISA" RELATED Gene-based [UniProtKB:Q7Z434]
synonym: "hMAVS" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1271" RELATED Gene-based [UniProtKB:Q7Z434]
synonym: "IPS-1 (human)" EXACT [UniProtKB:Q7Z434]
synonym: "cardif (human)" EXACT [UniProtKB:Q7Z434]
synonym: "virus-induced-signaling adapter (human)" EXACT [UniProtKB:Q7Z434]
synonym: "CARD adapter inducing interferon beta (human)" EXACT [UniProtKB:Q7Z434]
synonym: "putative NF-kappa-B-activating protein 031N (human)" EXACT [UniProtKB:Q7Z434]
synonym: "interferon beta promoter stimulator protein 1 (human)" EXACT [UniProtKB:Q7Z434]
xref: UniProtKB:Q7Z434
xref: Reactome:R-HSA-913730 "PR:Q7Z434 located_in GO:0005741"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010210 ! mitochondrial antiviral-signaling protein
relationship: has_gene_template HGNC:29233 ! MAVS (human)

[Term]
id: PR:000010210
name: mitochondrial antiviral-signaling protein
def: "A protein that is a translation product of the human MAVS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "IPS1" RELATED Gene-based []
synonym: "MAVS" EXACT PRO-short-label [PRO:DNx]
synonym: "VISA" RELATED Gene-based []
synonym: "IPS-1" EXACT []
synonym: "cardif" EXACT []
synonym: "KIAA1271" RELATED Gene-based []
synonym: "virus-induced-signaling adapter" EXACT []
synonym: "CARD adapter inducing interferon beta" EXACT []
synonym: "putative NF-kappa-B-activating protein 031N" EXACT []
synonym: "interferon beta promoter stimulator protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000048346
name: mitochondrial antiviral-signaling protein ubiquitinated 1 (human)
def: "A mitochondrial antiviral-signaling protein (human) that has been post-translationally modified to include ubiquitinated lysine at positions 371 and 420 of the amino acid sequence represented by UniProtKB:Q7Z434. UniProtKB:Q7Z434, Lys-371/Lys-420, MOD:01148." [PRO:DNx, Reactome:R-HSA-983463]
comment: Category=organism-modification.
synonym: "hMAVS/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q7Z434, Lys-371/Lys-420, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-983463 "PR:000048346 located_in GO:0005741"
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q7Z434-6
name: mitochondrial antiviral-signaling protein isoform h6 (human)
def: "A mitochondrial antiviral-signaling protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z434-6." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-sequence.
synonym: "hMAVS/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "mitochondrial antiviral-signaling protein isoform MAVS1a (human)" EXACT [UniProtKB:Q7Z434]
synonym: "mitochondrial antiviral-signaling protein isoform exon 2 deletion (human)" EXACT [UniProtKB:Q7Z434]
xref: UniProtKB:Q7Z434-6
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q7Z434-5
name: mitochondrial antiviral-signaling protein isoform h5 (human)
def: "A mitochondrial antiviral-signaling protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z434-5." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-sequence.
synonym: "hMAVS/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "mitochondrial antiviral-signaling protein isoform MAVS1b (human)" EXACT [UniProtKB:Q7Z434]
synonym: "mitochondrial antiviral-signaling protein isoform exon 3 deletion (human)" EXACT [UniProtKB:Q7Z434]
xref: UniProtKB:Q7Z434-5
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q7Z434-4
name: mitochondrial antiviral-signaling protein isoform h4 (human)
def: "A mitochondrial antiviral-signaling protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z434-4." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-sequence.
synonym: "hMAVS/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7Z434-4
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q7Z434-3
name: mitochondrial antiviral-signaling protein isoform h3 (human)
def: "A mitochondrial antiviral-signaling protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z434-3." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-sequence.
synonym: "hMAVS/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7Z434-3
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q7Z434-2
name: mitochondrial antiviral-signaling protein isoform h2 (human)
def: "A mitochondrial antiviral-signaling protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z434-2." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-sequence.
synonym: "hMAVS/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7Z434-2
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q7Z434-1
name: mitochondrial antiviral-signaling protein isoform h1 (human)
def: "A mitochondrial antiviral-signaling protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z434-1." [PRO:DNx, UniProtKB:Q7Z434]
comment: Category=organism-sequence.
synonym: "hMAVS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7Z434-1
is_a: PR:Q7Z434 ! mitochondrial antiviral-signaling protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens