[Term]
id: PR:000010199
name: microtubule-associated serine/threonine-protein kinase-like
def: "A protein that is a translation product of the human MASTL gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GW" RELATED Gene-based []
synonym: "GWL" RELATED Gene-based []
synonym: "THC2" RELATED Gene-based []
synonym: "MASTL" EXACT PRO-short-label [PRO:DNx]
synonym: "MAST-L" EXACT []
xref: IUPHARobj:1514
is_a: PR:000000001 ! protein

[Term]
id: PR:Q96GX5
name: serine/threonine-protein kinase greatwall (human)
def: "A microtubule-associated serine/threonine-protein kinase-like that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96GX5]
comment: Category=organism-gene.
synonym: "GW" RELATED Gene-based [UniProtKB:Q96GX5]
synonym: "GWL" RELATED Gene-based [UniProtKB:Q96GX5]
synonym: "THC2" RELATED Gene-based [UniProtKB:Q96GX5]
synonym: "hGWL" EXACT [UniProtKB:Q96GX5]
synonym: "MASTL" RELATED Gene-based [UniProtKB:Q96GX5]
synonym: "hMASTL" EXACT PRO-short-label [PRO:DNx]
synonym: "MAST-L (human)" EXACT [UniProtKB:Q96GX5]
synonym: "microtubule-associated serine/threonine-protein kinase-like (human)" EXACT [UniProtKB:Q96GX5]
xref: UniProtKB:Q96GX5
xref: Reactome:R-HSA-2160957 "PR:Q96GX5 located_in GO:0005654"
xref: DTO:03100169
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010199 ! microtubule-associated serine/threonine-protein kinase-like
relationship: has_gene_template HGNC:19042 ! MASTL (human)

[Term]
id: PR:Q96GX5-2
name: serine/threonine-protein kinase greatwall isoform h2 (human)
def: "A serine/threonine-protein kinase greatwall (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GX5-2." [PRO:DNx, UniProtKB:Q96GX5]
comment: Category=organism-sequence.
synonym: "hMASTL/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96GX5-2
is_a: PR:Q96GX5 ! serine/threonine-protein kinase greatwall (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96GX5-3
name: serine/threonine-protein kinase greatwall isoform h3 (human)
def: "A serine/threonine-protein kinase greatwall (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GX5-3." [PRO:DNx, UniProtKB:Q96GX5]
comment: Category=organism-sequence.
synonym: "hMASTL/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96GX5-3
is_a: PR:Q96GX5 ! serine/threonine-protein kinase greatwall (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96GX5-1
name: serine/threonine-protein kinase greatwall isoform h1 (human)
def: "A serine/threonine-protein kinase greatwall (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GX5-1." [PRO:DNx, UniProtKB:Q96GX5]
comment: Category=organism-sequence.
synonym: "hMASTL/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96GX5-1
is_a: PR:Q96GX5 ! serine/threonine-protein kinase greatwall (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048340
name: serine/threonine-protein kinase greatwall phosphorylated 1 (human)
def: "A serine/threonine-protein kinase greatwall (human) that has been post-translationally modified to include phosphothreonine at positions 194, 207 and 741 of the amino acid sequence represented by UniProtKB:Q96GX5. UniProtKB:Q96GX5, Thr-194/Thr-207/Thr-741, MOD:00047." [PRO:DNx, Reactome:R-HSA-2430549]
comment: Category=organism-modification.
synonym: "hMASTL/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q96GX5, Thr-194/Thr-207/Thr-741, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2430549 "PR:000048340 located_in GO:0005654"
is_a: PR:Q96GX5 ! serine/threonine-protein kinase greatwall (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens