[Term]
id: PR:000010188
name: MAP/microtubule affinity-regulating kinase 3
def: "A protein that is a translation product of the human MARK3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EMK2" RELATED Gene-based []
synonym: "CTAK1" RELATED Gene-based []
synonym: "EMK-2" EXACT []
synonym: "MARK3" EXACT PRO-short-label [PRO:DNx]
synonym: "Mpk10" RELATED Gene-based []
synonym: "cTAK1" EXACT []
synonym: "C-TAK1" EXACT []
synonym: "MPK-10" EXACT []
synonym: "ELKL motif kinase 2" EXACT []
synonym: "protein kinase STK10" EXACT []
synonym: "ser/Thr protein kinase PAR-1" EXACT []
synonym: "Cdc25C-associated protein kinase 1" EXACT []
synonym: "serine/threonine-protein kinase p78" EXACT []
xref: IUPHARobj:2099
is_a: PR:000000001 ! protein

[Term]
id: PR:P27448-8
name: MAP/microtubule affinity-regulating kinase 3 isoform h7 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27448-8." [PRO:DNx, UniProtKB:P27448]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:h7" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27448-8
is_a: PR:P27448 ! MAP/microtubule affinity-regulating kinase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27448-3
name: MAP/microtubule affinity-regulating kinase 3 isoform 3 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 isoform 3 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27448-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039167 ! MAP/microtubule affinity-regulating kinase 3 isoform 3

[Term]
id: PR:P27448-2
name: MAP/microtubule affinity-regulating kinase 3 isoform h2 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27448-2." [PRO:DNx, UniProtKB:P27448]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "MAP/microtubule affinity-regulating kinase 3 isoform CTAK75a (human)" EXACT [UniProtKB:P27448]
xref: UniProtKB:P27448-2
is_a: PR:P27448 ! MAP/microtubule affinity-regulating kinase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27448-7
name: MAP/microtubule affinity-regulating kinase 3 isoform h6 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27448-7." [PRO:DNx, UniProtKB:P27448]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27448-7
is_a: PR:P27448 ! MAP/microtubule affinity-regulating kinase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27448-6
name: MAP/microtubule affinity-regulating kinase 3 isoform h5 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27448-6." [PRO:DNx, UniProtKB:P27448]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "MAP/microtubule affinity-regulating kinase 3 isoform p58 (human)" EXACT [UniProtKB:P27448]
xref: UniProtKB:P27448-6
is_a: PR:P27448 ! MAP/microtubule affinity-regulating kinase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27448-5
name: MAP/microtubule affinity-regulating kinase 3 isoform h1 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27448-5." [PRO:DNx, UniProtKB:P27448]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27448-5
is_a: PR:P27448 ! MAP/microtubule affinity-regulating kinase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27448-4
name: MAP/microtubule affinity-regulating kinase 3 isoform 4 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 isoform 4 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMARK3/iso:4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27448-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039168 ! MAP/microtubule affinity-regulating kinase 3 isoform 4

[Term]
id: PR:P27448
name: MAP/microtubule affinity-regulating kinase 3 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27448]
comment: Category=organism-gene.
synonym: "EMK2" RELATED Gene-based [UniProtKB:P27448]
synonym: "CTAK1" RELATED Gene-based [UniProtKB:P27448]
synonym: "MARK3" RELATED Gene-based [UniProtKB:P27448]
synonym: "hMARK3" EXACT PRO-short-label [PRO:DNx]
synonym: "EMK-2 (human)" EXACT [UniProtKB:P27448]
synonym: "C-TAK1 (human)" EXACT [UniProtKB:P27448]
synonym: "Par-1a (human)" EXACT [UniProtKB:P27448]
synonym: "ELKL motif kinase 2 (human)" EXACT [UniProtKB:P27448]
synonym: "protein kinase STK10 (human)" EXACT [UniProtKB:P27448]
synonym: "ser/Thr protein kinase PAR-1 (human)" EXACT [UniProtKB:P27448]
synonym: "Cdc25C-associated protein kinase 1 (human)" EXACT [UniProtKB:P27448]
synonym: "serine/threonine-protein kinase p78 (human)" EXACT [UniProtKB:P27448]
xref: Reactome:R-HSA-5672591 "PR:P27448 located_in GO:0005829"
xref: DTO:03100304
xref: UniProtKB:P27448
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010188 ! MAP/microtubule affinity-regulating kinase 3
relationship: has_gene_template HGNC:6897 ! MARK3 (human)

[Term]
id: PR:000045731
name: MAP/microtubule affinity-regulating kinase 3 phosphorylated 1 (human)
def: "A MAP/microtubule affinity-regulating kinase 3 (human) that has been phosphorylated at the position equivalent to Thr-564 of the amino acid sequence represented by UniProtKB:P27448-5. Example: UniProtKB:P27448-5, Thr-564, MOD:00047." [PMID:15084291, iPTMnet:P27448]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15084291). Status=unreviewed.
synonym: "hMARK3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P27448-5, Thr-564, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P27448 ! MAP/microtubule affinity-regulating kinase 3 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens