[Term]
id: PR:Q556Y9
name: mitotic spindle assembly checkpoint protein MAD2A (Dictyostelium discoideum)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of Dictyostelium discoideum." [OMA:Q556Y9, PANTHER:PTHR11842:SF11, PRO:DNx]
comment: Category=organism-gene.
synonym: "mad2a-1" RELATED Gene-based [UniProtKB:Q556Y9]
synonym: "mad2a-2" RELATED Gene-based [UniProtKB:Q556Y9]
synonym: "mad2l1-1" RELATED Gene-based [UniProtKB:Q556Y9]
synonym: "mad2l1-2" RELATED Gene-based [UniProtKB:Q556Y9]
synonym: "DDB_G0273201" RELATED Gene-based [UniProtKB:Q556Y9]
synonym: "DDB_G0273727" RELATED Gene-based [UniProtKB:Q556Y9]
synonym: "Dicty-MAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAD2-like protein 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q556Y9]
synonym: "mitotic arrest deficient 2-like protein 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q556Y9]
xref: UniProtKB:Q556Y9
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template dictyBase:DDB_G0273201 ! mad2l1-2 copy 1 (Dictyostelium discoideum)
relationship: has_gene_template dictyBase:DDB_G0273727 ! mad2l1-2 copy 2 (Dictyostelium discoideum)

[Term]
id: PR:Q59VQ3
name: spindle assembly checkpoint component MAD2 (Candida albicans SC5314)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of Candida albicans SC5314." [OMA:Q59VQ3, PRO:DNx]
comment: Category=organism-gene. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DNx.
synonym: "MAD2" RELATED Gene-based [UniProtKB:Q59VQ3]
synonym: "CaO19.1040" RELATED Gene-based [UniProtKB:Q59VQ3]
synonym: "CaO19.8642" RELATED Gene-based [UniProtKB:Q59VQ3]
synonym: "Calb-MAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "CAALFM_C104080WA" RELATED Gene-based [UniProtKB:Q59VQ3]
xref: UniProtKB:Q59VQ3
intersection_of: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template NCBIGene:3644696 ! MAD2 (Candida albicans SC5314)

[Term]
id: PR:P40958
name: mitotic spindle checkpoint component MAD2 (yeast)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of yeast." [OMA:P40958, PMID:15249665, PMID:15514023, PMID:17504936, PRO:KER]
comment: Category=organism-gene.
synonym: "MAD2" RELATED Gene-based [UniProtKB:P40958]
synonym: "J1256" RELATED Gene-based [UniProtKB:P40958]
synonym: "YJL030W" RELATED Gene-based [UniProtKB:P40958]
synonym: "yMAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitotic MAD2 protein (yeast)" EXACT [UniProtKB:P40958]
xref: UniProtKB:P40958
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template SGD:S000003567 ! MAD2 (yeast)

[Term]
id: PR:O14417
name: mitotic spindle checkpoint component mad2 (Schizosaccharomyces pombe 972h-)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O14417, PRO:KER]
comment: Category=organism-gene.
synonym: "mad2" RELATED Gene-based [UniProtKB:O14417]
synonym: "SPBC20F10.06" RELATED Gene-based [UniProtKB:O14417]
synonym: "Spom972h-MAD2L1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14417
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template PomBase:SPBC20F10.06 ! mad2 (Schizosaccharomyces pombe)

[Term]
id: PR:Q9Z1B5
name: mitotic spindle assembly checkpoint protein MAD2A (mouse)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of mouse." [OMA:Q9Z1B5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mad2a" RELATED Gene-based [UniProtKB:Q9Z1B5]
synonym: "Mad2l1" RELATED Gene-based [UniProtKB:Q9Z1B5]
synonym: "mMAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAD2-like protein 1 (mouse)" EXACT [UniProtKB:Q9Z1B5]
synonym: "mitotic arrest deficient 2-like protein 1 (mouse)" EXACT [UniProtKB:Q9Z1B5]
xref: UniProtKB:Q9Z1B5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template MGI:1860374 ! Mad2l1 (mouse)

[Term]
id: PR:000010038
name: mitotic spindle assembly checkpoint protein MAD2A
def: "A protein that is a translation product of the human MAD2L1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MAD2" RELATED Gene-based []
synonym: "Mad2a" RELATED Gene-based []
synonym: "MAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAD2-like protein 1" EXACT []
synonym: "mitotic arrest deficient 2-like protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P79935
name: mitotic spindle assembly checkpoint protein MAD2A (frog)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of frog." [PRO:KER]
comment: Category=organism-gene.
synonym: "frog-MAD2L1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P79935
intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template NCBIGene:380433 ! mad2l1 (frog)

[Term]
id: PR:Q9LU93-1
name: mitotic spindle checkpoint protein MAD2 isoform 1 (Arabidopsis thaliana)
def: "A mitotic spindle checkpoint protein MAD2 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9LU93-1." [PRO:DNx, UniProtKB:Q9LU93]
comment: Category=organism-sequence.
synonym: "At-MAD2L1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9LU93-1
is_a: PR:Q9LU93 ! mitotic spindle checkpoint protein MAD2 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:000020518
name: mitotic spindle assembly checkpoint protein MAD2A, initiator methionine removed form
def: "A mitotic spindle assembly checkpoint protein MAD2A that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "MAD2L1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000040405
name: mitotic spindle assembly checkpoint protein MAD2A isoform 1
def: "A mitotic spindle assembly checkpoint protein MAD2A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13257-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "MAD2L1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A

[Term]
id: PR:Q9Z1B5-1
name: mitotic spindle assembly checkpoint protein MAD2A isoform 1 (mouse)
def: "A mitotic spindle assembly checkpoint protein MAD2A isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMAD2L1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z1B5-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040405 ! mitotic spindle assembly checkpoint protein MAD2A isoform 1

[Term]
id: PR:Q13257
name: mitotic spindle assembly checkpoint protein MAD2A (human)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of human." [PMID:12719470, PMID:15525512, PMID:15592459, PMID:20624902, PRO:KER]
comment: Category=organism-gene.
synonym: "MAD2" RELATED Gene-based [UniProtKB:Q13257]
synonym: "HsMAD2" EXACT [UniProtKB:Q13257]
synonym: "MAD2L1" RELATED Gene-based [UniProtKB:Q13257]
synonym: "hMAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAD2-like protein 1 (human)" EXACT [UniProtKB:Q13257]
synonym: "mitotic arrest deficient 2-like protein 1 (human)" EXACT [UniProtKB:Q13257]
xref: UniProtKB:Q13257
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template HGNC:6763 ! MAD2L1 (human)

[Term]
id: PR:Q9LU93
name: mitotic spindle checkpoint protein MAD2 (Arabidopsis thaliana)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9LU93, PANTHER:PTHR11842:SF11, PRO:DNx]
comment: Category=organism-gene.
synonym: "MAD2" RELATED Gene-based [UniProtKB:Q9LU93]
synonym: "MPE11.15" RELATED Gene-based [UniProtKB:Q9LU93]
synonym: "At-MAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "At3g25980" RELATED Gene-based [UniProtKB:Q9LU93]
synonym: "mitotic arrest deficient protein 2 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9LU93]
xref: UniProtKB:Q9LU93
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
relationship: has_gene_template Araport:AT3G25980 ! MAD2 (Arabidopsis thaliana)

[Term]
id: PR:Q13257-2
name: mitotic spindle assembly checkpoint protein MAD2A isoform h2 (human)
def: "A mitotic spindle assembly checkpoint protein MAD2A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13257-2." [PRO:DNx, UniProtKB:Q13257]
comment: Category=organism-sequence.
synonym: "hMAD2L1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13257-2
is_a: PR:Q13257 ! mitotic spindle assembly checkpoint protein MAD2A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13257-1
name: mitotic spindle assembly checkpoint protein MAD2A isoform 1 (human)
def: "A mitotic spindle assembly checkpoint protein MAD2A isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMAD2L1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13257-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040405 ! mitotic spindle assembly checkpoint protein MAD2A isoform 1

[Term]
id: PR:000042259
name: mitotic spindle assembly checkpoint protein MAD2A, initiator methionine removed form (human)
def: "A mitotic spindle assembly checkpoint protein MAD2A (human) that has had the initiator methionine removed. Example: UniProtKB:Q13257-1, 2-205." [PRO:DAN]
comment: Category=organism-modification.
synonym: "PRO_0000126117" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "hMAD2L1/InitMet-" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q13257-1, 2-205" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-141400 "PR:000042259 located_in GO:0005829"
xref: Reactome:R-HSA-141447 "PR:000042259 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q13257 ! mitotic spindle assembly checkpoint protein MAD2A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens