[Term]
id: PR:P48449-1
name: lanosterol synthase isoform h1 (human)
def: "A lanosterol synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48449-1." [PRO:DNx, UniProtKB:P48449]
comment: Category=organism-sequence.
synonym: "hLSS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48449-1
is_a: PR:P48449 ! lanosterol synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48449-3
name: lanosterol synthase isoform h3 (human)
def: "A lanosterol synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48449-3." [PRO:DNx, UniProtKB:P48449]
comment: Category=organism-sequence.
synonym: "hLSS/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48449-3
is_a: PR:P48449 ! lanosterol synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48449-2
name: lanosterol synthase isoform h2 (human)
def: "A lanosterol synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48449-2." [PRO:DNx, UniProtKB:P48449]
comment: Category=organism-sequence.
synonym: "hLSS/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48449-2
is_a: PR:P48449 ! lanosterol synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048264
name: lanosterol synthase, initiator methionine removed form (human)
def: "A lanosterol synthase (human) that has had the initiator methionine removed. UniProtKB:P48449, 2-732." [PRO:DNx, Reactome:R-HSA-191371]
comment: Category=organism-modification.
synonym: "hLSS/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000072659" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P48449, 2-732" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-191371 "PR:000048264 located_in GO:0005789"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P48449 ! lanosterol synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48449
name: lanosterol synthase (human)
def: "A lanosterol synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P48449]
comment: Category=organism-gene.
synonym: "LSS" RELATED Gene-based [UniProtKB:P48449]
synonym: "OSC" RELATED Gene-based [UniProtKB:P48449]
synonym: "hLSS" EXACT PRO-short-label [PRO:DNx]
synonym: "hOSC" EXACT [UniProtKB:P48449]
synonym: "oxidosqualene--lanosterol cyclase (human)" EXACT [UniProtKB:P48449]
synonym: "2,3-epoxysqualene--lanosterol cyclase (human)" EXACT [UniProtKB:P48449]
xref: UniProtKB:P48449
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009969 ! lanosterol synthase
relationship: has_gene_template HGNC:6708 ! LSS (human)

[Term]
id: PR:000009969
name: lanosterol synthase
def: "A protein that is a translation product of the human LSS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LSS" EXACT PRO-short-label [PRO:DNx]
synonym: "OSC" RELATED Gene-based []
synonym: "oxidosqualene--lanosterol cyclase" EXACT []
synonym: "2,3-epoxysqualene--lanosterol cyclase" EXACT []
xref: IUPHARobj:2434
is_a: PR:000000001 ! protein