[Term]
id: PR:000009927
name: low-density lipoprotein receptor-related protein 6
def: "A protein that is a translation product of the human LRP6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LRP6" EXACT PRO-short-label [PRO:DNx]
synonym: "LRP-6" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O75581-1
name: low-density lipoprotein receptor-related protein 6 isoform 1 (human)
def: "A low-density lipoprotein receptor-related protein 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hLRP6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75581-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038376 ! low-density lipoprotein receptor-related protein 6 isoform 1

[Term]
id: PR:000046118
name: low-density lipoprotein receptor-related protein 6 phosphorylated 1 (mouse)
def: "A low-density lipoprotein receptor-related protein 6 (mouse) that has been phosphorylated at Ser-1579. UniProtKB:O88572, Ser-1579, MOD:00046." [PMID:22491013, iPTMnet:O88572]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22491013). Status=unreviewed.
synonym: "mLrp6/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O88572, Ser-1579, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O88572 ! low-density lipoprotein receptor-related protein 6 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000048251
name: low-density lipoprotein receptor-related protein 6, signal peptide removed form (human)
def: "A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed. UniProtKB:O75581, 20-1613." [PRO:DNx, Reactome:R-HSA-206252, Reactome:R-HSA-5368481]
comment: Category=organism-modification.
synonym: "hLRP6/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000017330" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:O75581, 20-1613" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-206252 "PR:000048251 located_in GO:0005886"
xref: Reactome:R-HSA-5368481 "PR:000048251 located_in GO:0031901"
intersection_of: PR:O75581 ! low-density lipoprotein receptor-related protein 6 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O88572-1
name: low-density lipoprotein receptor-related protein 6 isoform 1 (mouse)
def: "A low-density lipoprotein receptor-related protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mLRP6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88572-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038376 ! low-density lipoprotein receptor-related protein 6 isoform 1

[Term]
id: PR:O75581
name: low-density lipoprotein receptor-related protein 6 (human)
def: "A low-density lipoprotein receptor-related protein 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75581]
comment: Category=organism-gene.
synonym: "LRP6" RELATED Gene-based [UniProtKB:O75581]
synonym: "hLRP6" EXACT PRO-short-label [PRO:DNx]
synonym: "LRP-6 (human)" EXACT [UniProtKB:O75581]
xref: UniProtKB:O75581
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009927 ! low-density lipoprotein receptor-related protein 6
relationship: has_gene_template HGNC:6698 ! LRP6 (human)

[Term]
id: PR:O88572
name: low-density lipoprotein receptor-related protein 6 (mouse)
def: "A low-density lipoprotein receptor-related protein 6 that is encoded in the genome of mouse." [OMA:O88572, PRO:DNx]
comment: Category=organism-gene.
synonym: "Lrp6" RELATED Gene-based [UniProtKB:O88572]
synonym: "mLRP6" EXACT PRO-short-label [PRO:DNx]
synonym: "LRP-6 (mouse)" EXACT [UniProtKB:O88572]
xref: UniProtKB:O88572
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009927 ! low-density lipoprotein receptor-related protein 6
relationship: has_gene_template MGI:1298218 ! Lrp6 (mouse)

[Term]
id: PR:000038376
name: low-density lipoprotein receptor-related protein 6 isoform 1
def: "A low-density lipoprotein receptor-related protein 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75581-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "LRP6/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009927 ! low-density lipoprotein receptor-related protein 6