[Term]
id: PR:000026541
name: prelamin-A/C isoform C
def: "A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-2 or a 1:1 ortholog thereof." [PMID:10080180]
comment: Category=sequence.
synonym: "LMNA/iso:C" EXACT PRO-short-label [PRO:DNx]
synonym: "prelamin-A/C isoform 2" EXACT [PRO:DNx]
is_a: PR:000009859 ! prelamin-A/C

[Term]
id: PR:P48678-2
name: prelamin-A/C isoform C (mouse)
def: "A prelamin-A/C isoform C that is encoded in the genome of mouse." [PMID:2719959, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mLMNA/iso:C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48678-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026541 ! prelamin-A/C isoform C

[Term]
id: PR:P48678-1
name: prelamin-A/C isoform A (mouse)
def: "A prelamin-A/C isoform A that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mLMNA/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48678-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026539 ! prelamin-A/C isoform A

[Term]
id: PR:P48678-3
name: prelamin-A/C isoform C2 (mouse)
def: "A prelamin-A/C isoform C2 that is encoded in the genome of mouse." [PMID:8187835, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mLMNA/iso:C2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48678-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037391 ! prelamin-A/C isoform C2

[Term]
id: PR:P02545-3
name: prelamin-A/C isoform ADelta10 (human)
def: "A prelamin-A/C isoform C2 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hLMNA/iso:ADelta10" EXACT PRO-short-label [PRO:DNx]
synonym: "prelamin-A/C isoform Lamin ADelta10 (human)" EXACT [UniProtKB:P02545]
xref: UniProtKB:P02545-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037391 ! prelamin-A/C isoform C2

[Term]
id: PR:P48679
name: prelamin-A/C (rat)
def: "A prelamin-A/C that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Lmn1" RELATED Gene-based [UniProtKB:P48679]
synonym: "Lmna" RELATED Gene-based [UniProtKB:P48679]
synonym: "rLMNA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48679
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000009859 ! prelamin-A/C
relationship: has_gene_template RGD:620456 ! Lmna (rat)

[Term]
id: PR:Q54HI5
name: lamin-like protein (Dictyostelium discoideum)
def: "A prelamin-A/C that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]
comment: Category=organism-gene.
synonym: "lmnB" RELATED Gene-based [UniProtKB:Q54HI5]
synonym: "Dicty-LMNA" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0289429" RELATED Gene-based [UniProtKB:Q54HI5]
synonym: "protein NE81 (Dictyostelium discoideum)" EXACT [UniProtKB:Q54HI5]
xref: UniProtKB:Q54HI5
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000009859 ! prelamin-A/C
relationship: has_gene_template dictyBase:DDB_G0289429 ! lmnB (Dictyostelium discoideum)

[Term]
id: PR:000037391
name: prelamin-A/C isoform C2
def: "A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-3 or a 1:1 ortholog thereof." [PMID:8187835, PRO:HJD]
comment: Category=sequence.
synonym: "LMNA/iso:C2" EXACT PRO-short-label [PRO:DNx]
synonym: "lamin ADelta10" EXACT [UniProtKB:P02545]
is_a: PR:000009859 ! prelamin-A/C

[Term]
id: PR:P02545-6
name: prelamin-A/C isoform h6 (human)
def: "A prelamin-A/C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-6." [PRO:DNx, UniProtKB:P02545]
comment: Category=organism-sequence.
synonym: "hLMNA/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "prelamin-A/C isoform Progerin (human)" EXACT [UniProtKB:P02545]
xref: UniProtKB:P02545-6
is_a: PR:P02545 ! prelamin-A/C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P02545-4
name: prelamin-A/C isoform h4 (human)
def: "A prelamin-A/C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-4." [PRO:DNx, UniProtKB:P02545]
comment: Category=organism-sequence.
synonym: "hLMNA/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P02545-4
is_a: PR:P02545 ! prelamin-A/C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P02545-5
name: prelamin-A/C isoform h5 (human)
def: "A prelamin-A/C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-5." [PRO:DNx, UniProtKB:P02545]
comment: Category=organism-sequence.
synonym: "hLMNA/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P02545-5
is_a: PR:P02545 ! prelamin-A/C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P02545-2
name: prelamin-A/C isoform C (human)
def: "A prelamin-A/C isoform C that is encoded in the genome of human." [PMID:10080180]
comment: Category=organism-sequence.
synonym: "hLMNA/iso:C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P02545-2
xref: Reactome:R-HSA-264872 "PR:P02545-2 located_in GO:0005654"
xref: Reactome:R-HSA-912378 "PR:P02545-2 located_in GO:0005635"
xref: Reactome:R-HSA-2995387 "PR:P02545-2 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026541 ! prelamin-A/C isoform C

[Term]
id: PR:000009859
name: prelamin-A/C
def: "A protein that is a translation product of the human LMNA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LMN1" RELATED Gene-based []
synonym: "LMNA" EXACT PRO-short-label [PRO:DNx]
synonym: "lamin-A/C" RELATED []
synonym: "70 kDa lamin" EXACT []
synonym: "renal carcinoma antigen NY-REN-32" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P48679-1
name: prelamin-A/C isoform Lamin A (rat)
def: "A prelamin-A/C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48679-1." [PRO:DNx, UniProtKB:P48679]
comment: Category=organism-sequence.
synonym: "rLMNA/iso:Lamin A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48679-1
is_a: PR:P48679 ! prelamin-A/C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P02545-1
name: prelamin-A/C isoform A (human)
def: "A prelamin-A/C isoform A that is encoded in the genome of human." [PMID:10080180]
comment: Category=organism-sequence.
synonym: "hLMNA/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P02545-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026539 ! prelamin-A/C isoform A

[Term]
id: PR:P48679-2
name: prelamin-A/C isoform Lamin C (rat)
def: "A prelamin-A/C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48679-2." [PRO:DNx, UniProtKB:P48679]
comment: Category=organism-sequence.
synonym: "rLMNA/iso:Lamin C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48679-2
is_a: PR:P48679 ! prelamin-A/C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P13648
name: lamin-A (chicken)
def: "A prelamin-A/C that is encoded in the genome of chicken." [PRO:DAN]
comment: Category=organism-gene.
synonym: "LMNA" RELATED Gene-based [UniProtKB:P13648]
synonym: "chick-LMNA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P13648
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000009859 ! prelamin-A/C
relationship: has_gene_template NCBIGene:396224 ! LMNA (chicken)

[Term]
id: PR:000026539
name: prelamin-A/C isoform A
def: "A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-1 or a 1:1 ortholog thereof." [PMID:10080180]
comment: Category=sequence.
synonym: "LMNA/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "prelamin-A/C isoform 1" EXACT [PRO:DNx]
is_a: PR:000009859 ! prelamin-A/C

[Term]
id: PR:P48678
name: prelamin-A/C (mouse)
def: "A prelamin-A/C that is encoded in the genome of mouse." [OMA:P48678, PRO:DNx]
comment: Category=organism-gene.
synonym: "Lmn1" RELATED Gene-based [UniProtKB:P48678]
synonym: "Lmna" RELATED Gene-based [UniProtKB:P48678]
synonym: "mLMNA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48678
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009859 ! prelamin-A/C
relationship: has_gene_template MGI:96794 ! Lmna (mouse)

[Term]
id: PR:P02545
name: prelamin-A/C (human)
def: "A prelamin-A/C that is encoded in the genome of human." [PRO:DNx, UniProtKB:P02545]
comment: Category=organism-gene.
synonym: "LMN1" RELATED Gene-based [UniProtKB:P02545]
synonym: "LMNA" RELATED Gene-based [UniProtKB:P02545]
synonym: "hLMNA" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-535479 "PR:P02545 located_in GO:0005654"
xref: UniProtKB:P02545
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009859 ! prelamin-A/C
relationship: has_gene_template HGNC:6636 ! LMNA (human)