[Term] id: PR:Q9R0J8 name: legumain (rat) def: "A legumain that is encoded in the genome of rat." [PANTHER:PTHR12000:SF3, PRO:DNx] comment: Category=organism-gene. synonym: "Lgmn" RELATED Gene-based [UniProtKB:Q9R0J8] synonym: "Prsc1" RELATED Gene-based [UniProtKB:Q9R0J8] synonym: "rLGMN" EXACT PRO-short-label [PRO:DNx] synonym: "protease, cysteine 1 (rat)" EXACT [UniProtKB:Q9R0J8] synonym: "asparaginyl endopeptidase (rat)" EXACT [UniProtKB:Q9R0J8] xref: UniProtKB:Q9R0J8 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000009780 ! legumain relationship: has_gene_template RGD:619832 ! Lgmn (rat) [Term] id: PR:O89017 name: legumain (mouse) def: "A legumain that is encoded in the genome of mouse." [OMA:O89017, PRO:DNx] comment: Category=organism-gene. synonym: "Lgmn" RELATED Gene-based [UniProtKB:O89017] synonym: "Prsc1" RELATED Gene-based [UniProtKB:O89017] synonym: "mLGMN" EXACT PRO-short-label [PRO:DNx] synonym: "protease, cysteine 1 (mouse)" EXACT [UniProtKB:O89017] synonym: "asparaginyl endopeptidase (mouse)" EXACT [UniProtKB:O89017] xref: UniProtKB:O89017 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000009780 ! legumain relationship: has_gene_template MGI:1330838 ! Lgmn (mouse) [Term] id: PR:Q99538 name: legumain (human) def: "A legumain that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99538] comment: Category=organism-gene. synonym: "LGMN" RELATED Gene-based [UniProtKB:Q99538] synonym: "PRSC1" RELATED Gene-based [UniProtKB:Q99538] synonym: "hLGMN" EXACT PRO-short-label [PRO:DNx] synonym: "protease, cysteine 1 (human)" EXACT [UniProtKB:Q99538] synonym: "asparaginyl endopeptidase (human)" EXACT [UniProtKB:Q99538] xref: UniProtKB:Q99538 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000009780 ! legumain relationship: has_gene_template HGNC:9472 ! LGMN (human) [Term] id: PR:Q9R0J8-1 name: legumain isoform 1 (rat) def: "A legumain isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rLGMN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9R0J8-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000038453 ! legumain isoform 1 [Term] id: PR:Q99538-2 name: legumain isoform h2 (human) def: "A legumain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99538-2." [PRO:DNx, UniProtKB:Q99538] comment: Category=organism-sequence. synonym: "hLGMN/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q99538-2 is_a: PR:Q99538 ! legumain (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057934 name: legumain O-glycosylated 1 (human) def: "A legumain (human) that has been O-glycosylated at the residue equivalent to Ser-307 of the amino acid sequence represented by UniProtKB:Q99538-1, in which the glycan composition is represented by GlyTouCan:G17015OC. Example: UniProtKB:Q99538-1, Ser-307, MOD:00002~GNO:G17015OC." [GlyGen:Q99538-1, PMID:26598643, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hLGMN/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q99538-1, Ser-307, MOD:00002~GNO:G17015OC" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q99538 ! legumain (human) relationship: has_part GNO:G17015OC ! G17015OC relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057935 name: legumain O-glycosylated 2 (human) def: "A legumain (human) that has been O-glycosylated at the residue equivalent to Thr-305 of the amino acid sequence represented by UniProtKB:Q99538-1, in which the glycan composition is represented by GlyTouCan:G17015OC. Example: UniProtKB:Q99538-1, Thr-305, MOD:00005~GNO:G17015OC." [GlyGen:Q99538-1, PMID:26598643, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hLGMN/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q99538-1, Thr-305, MOD:00005~GNO:G17015OC" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q99538 ! legumain (human) relationship: has_part GNO:G17015OC ! G17015OC relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O89017-1 name: legumain isoform 1 (mouse) def: "A legumain isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mLGMN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O89017-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000038453 ! legumain isoform 1 [Term] id: PR:Q99538-3 name: legumain isoform h3 (human) def: "A legumain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99538-3." [PRO:DNx, UniProtKB:Q99538] comment: Category=organism-sequence. synonym: "hLGMN/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q99538-3 is_a: PR:Q99538 ! legumain (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q99538-1 name: legumain isoform h1 (human) def: "A legumain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99538-1." [PRO:DNx, UniProtKB:Q99538] comment: Category=organism-sequence. synonym: "hLGMN/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q99538-1 is_a: PR:Q99538 ! legumain (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000038453 name: legumain isoform 1 def: "A legumain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O89017-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "LGMN/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000009780 ! legumain [Term] id: PR:000009780 name: legumain def: "A protein that is a translation product of the human LGMN gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "LGMN" EXACT PRO-short-label [PRO:DNx] synonym: "PRSC1" RELATED Gene-based [] synonym: "protease, cysteine 1" EXACT [] synonym: "asparaginyl endopeptidase" EXACT [] xref: IUPHARobj:2380 is_a: PR:000000001 ! protein [Term] id: PR:000020462 name: legumain, signal peptide removed form def: "A legumain that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "LGMN/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000009780 ! legumain intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000020463 name: legumain proteolytic cleavage product def: "A legumain that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "LGMN/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000009780 ! legumain