[Term]
id: PR:000009771
name: galectin-3
def: "A protein that is a translation product of the human LGALS3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "L-31" EXACT []
synonym: "MAC2" RELATED Gene-based []
synonym: "GALBP" EXACT []
synonym: "gal-3" EXACT []
synonym: "CBP 35" EXACT []
synonym: "LGALS3" EXACT PRO-short-label [PRO:DNx]
synonym: "lectin L-29" EXACT []
synonym: "35 kDa lectin" EXACT []
synonym: "Mac-2 antigen" EXACT []
synonym: "IgE-binding protein" EXACT []
synonym: "laminin-binding protein" EXACT []
synonym: "galactose-specific lectin 3" EXACT []
synonym: "galactoside-binding protein" EXACT []
synonym: "L-34 galactoside-binding lectin" EXACT []
synonym: "carbohydrate-binding protein 35" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P17931
name: galectin-3 (human)
def: "A galectin-3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17931]
comment: Category=organism-gene.
synonym: "MAC2" RELATED Gene-based [UniProtKB:P17931]
synonym: "LGALS3" RELATED Gene-based [UniProtKB:P17931]
synonym: "hLGALS3" EXACT PRO-short-label [PRO:DNx]
synonym: "L-31 (human)" EXACT [UniProtKB:P17931]
synonym: "GALBP (human)" EXACT [UniProtKB:P17931]
synonym: "gal-3 (human)" EXACT [UniProtKB:P17931]
synonym: "CBP 35 (human)" EXACT [UniProtKB:P17931]
synonym: "lectin L-29 (human)" EXACT [UniProtKB:P17931]
synonym: "35 kDa lectin (human)" EXACT [UniProtKB:P17931]
synonym: "Mac-2 antigen (human)" EXACT [UniProtKB:P17931]
synonym: "IgE-binding protein (human)" EXACT [UniProtKB:P17931]
synonym: "laminin-binding protein (human)" EXACT [UniProtKB:P17931]
synonym: "galactose-specific lectin 3 (human)" EXACT [UniProtKB:P17931]
synonym: "galactoside-binding protein (human)" EXACT [UniProtKB:P17931]
synonym: "carbohydrate-binding protein 35 (human)" EXACT [UniProtKB:P17931]
xref: UniProtKB:P17931
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009771 ! galectin-3
relationship: has_gene_template HGNC:6563 ! LGALS3 (human)

[Term]
id: PR:000048187
name: galectin-3, initiator methionine removed form (human)
def: "A galectin-3 (human) that has had the initiator methionine removed. UniProtKB:P17931, 2-250." [PRO:DNx, Reactome:R-HSA-879445]
comment: Category=organism-modification.
synonym: "PRO_0000076930" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hLGALS3/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17931, 2-250" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-879445 "PR:000048187 located_in GO:0005886"
xref: Reactome:R-HSA-6803307 "PR:000048187 located_in GO:0101003"
xref: Reactome:R-HSA-6803327 "PR:000048187 located_in GO:0030667"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P17931 ! galectin-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045696
name: galectin-3 phosphorylated 1 (human)
def: "A galectin-3 (human) that has been phosphorylated at Tyr-107. UniProtKB:P17931, Tyr-107, MOD:00048." [PMID:22232548, iPTMnet:P17931]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22232548). Status=unreviewed.
synonym: "hLGALS3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17931, Tyr-107, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P17931 ! galectin-3 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens