[Term]
id: PR:P01130
name: low-density lipoprotein receptor (human)
def: "A low-density lipoprotein receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-gene.
synonym: "LDLR" RELATED Gene-based [UniProtKB:P01130]
synonym: "hLDLR" EXACT PRO-short-label [PRO:DNx]
synonym: "LDL receptor (human)" EXACT [UniProtKB:P01130]
xref: UniProtKB:P01130
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009744 ! low-density lipoprotein receptor
relationship: has_gene_template HGNC:6547 ! LDLR (human)

[Term]
id: PR:000051629
name: low-density lipoprotein receptor O-glycosylated 1 (human)
def: "A low-density lipoprotein receptor (human) that has been O-glycosylated at the residue equivalent to Ser-768 of the amino acid sequence represented by UniProtKB:P01130-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01130-1, Ser-768, MOD:00002~GNO:G29068FM." [GlyGen:P01130-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hLDLR/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01130-1, Ser-768, MOD:00002~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051631
name: low-density lipoprotein receptor O-glycosylated 3 (human)
def: "A low-density lipoprotein receptor (human) that has been O-glycosylated at the residue equivalent to Thr-108 of the amino acid sequence represented by UniProtKB:P01130-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01130-1, Thr-108, MOD:00005~GNO:G43417UB." [GlyGen:P01130-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hLDLR/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01130-1, Thr-108, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051630
name: low-density lipoprotein receptor O-glycosylated 2 (human)
def: "A low-density lipoprotein receptor (human) that has been O-glycosylated at the residue equivalent to Ser-768 of the amino acid sequence represented by UniProtKB:P01130-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01130-1, Ser-768, MOD:00002~GNO:G43417UB." [GlyGen:P01130-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hLDLR/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01130-1, Ser-768, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048183
name: low-density lipoprotein receptor, signal peptide removed form (human)
def: "A low-density lipoprotein receptor (human) that has had the signal peptide removed. UniProtKB:P01130, 22-860." [PRO:DNx, Reactome:R-HSA-171053, Reactome:R-HSA-171105, Reactome:R-HSA-171127, Reactome:R-HSA-6784818]
comment: Category=organism-modification.
synonym: "hLDLR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000017312" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P01130, 22-860" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-171053 "PR:000048183 located_in GO:0005886"
xref: Reactome:R-HSA-171105 "PR:000048183 located_in GO:0030669"
xref: Reactome:R-HSA-171127 "PR:000048183 located_in GO:0010008"
xref: Reactome:R-HSA-6784818 "PR:000048183 located_in GO:0036020"
intersection_of: PR:P01130 ! low-density lipoprotein receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051632
name: low-density lipoprotein receptor O-glycosylated 4 (human)
def: "A low-density lipoprotein receptor (human) that has been O-glycosylated at the residue equivalent to Thr-235 of the amino acid sequence represented by UniProtKB:P01130-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01130-1, Thr-235, MOD:00005~GNO:G43417UB." [GlyGen:P01130-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hLDLR/OGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01130-1, Thr-235, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01130-3
name: low-density lipoprotein receptor isoform h3 (human)
def: "A low-density lipoprotein receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01130-3." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-sequence.
synonym: "hLDLR/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01130-3
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000020455
name: low-density lipoprotein receptor, signal peptide removed form
def: "A low-density lipoprotein receptor that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "LDLR/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000009744 ! low-density lipoprotein receptor
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P35951
name: low-density lipoprotein receptor (mouse)
def: "A low-density lipoprotein receptor that is encoded in the genome of mouse." [OMA:P35951, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ldlr" RELATED Gene-based [UniProtKB:P35951]
synonym: "mLDLR" EXACT PRO-short-label [PRO:DNx]
synonym: "LDL receptor (mouse)" EXACT [UniProtKB:P35951]
xref: UniProtKB:P35951
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009744 ! low-density lipoprotein receptor
relationship: has_gene_template MGI:96765 ! Ldlr (mouse)

[Term]
id: PR:P35952
name: low-density lipoprotein receptor (rat)
def: "A low-density lipoprotein receptor that is encoded in the genome of rat." [PANTHER:PTHR10529:SF102, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ldlr" RELATED Gene-based [UniProtKB:P35952]
synonym: "rLDLR" EXACT PRO-short-label [PRO:DNx]
synonym: "LDL receptor (rat)" EXACT [UniProtKB:P35952]
xref: UniProtKB:P35952
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000009744 ! low-density lipoprotein receptor
relationship: has_gene_template RGD:2998 ! Ldlr (rat)

[Term]
id: PR:P01130-6
name: low-density lipoprotein receptor isoform h6 (human)
def: "A low-density lipoprotein receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01130-6." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-sequence.
synonym: "hLDLR/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01130-6
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01130-5
name: low-density lipoprotein receptor isoform h5 (human)
def: "A low-density lipoprotein receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01130-5." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-sequence.
synonym: "hLDLR/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01130-5
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01130-4
name: low-density lipoprotein receptor isoform h4 (human)
def: "A low-density lipoprotein receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01130-4." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-sequence.
synonym: "hLDLR/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01130-4
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000009744
name: low-density lipoprotein receptor
def: "A protein that is a translation product of the human LDLR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LDLR" EXACT PRO-short-label [PRO:DNx]
synonym: "LDL receptor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P01130-2
name: low-density lipoprotein receptor isoform h2 (human)
def: "A low-density lipoprotein receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01130-2." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-sequence.
synonym: "hLDLR/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01130-2
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01130-1
name: low-density lipoprotein receptor isoform h1 (human)
def: "A low-density lipoprotein receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01130-1." [PRO:DNx, UniProtKB:P01130]
comment: Category=organism-sequence.
synonym: "hLDLR/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01130-1
is_a: PR:P01130 ! low-density lipoprotein receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens