[Term]
id: PR:000009433
name: importin subunit alpha-1
def: "A protein that is a translation product of the human KPNA2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RCH1" RELATED Gene-based []
synonym: "SRP1" RELATED Gene-based []
synonym: "KPNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "PTAC58" EXACT []
synonym: "pendulin" EXACT []
synonym: "SRP1-alpha" EXACT []
synonym: "importin alpha P1" EXACT []
synonym: "RAG cohort protein 1" EXACT []
synonym: "karyopherin subunit alpha-2" EXACT []
synonym: "pore targeting complex 58 kDa subunit" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P52295
name: importin subunit alpha (fruit fly)
def: "An importin subunit alpha-1 that is encoded in the genome of fruit fly." [OMA:P52295, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pen" RELATED Gene-based [UniProtKB:P52295]
synonym: "CG4799" RELATED Gene-based [UniProtKB:P52295]
synonym: "fly-KPNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "pendulin (fruit fly)" EXACT [UniProtKB:P52295]
synonym: "karyopherin subunit alpha (fruit fly)" EXACT [UniProtKB:P52295]
xref: UniProtKB:P52295
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000009433 ! importin subunit alpha-1
relationship: has_gene_template FlyBase:FBgn0287720 ! Pen (fruit fly)

[Term]
id: PR:P52293
name: importin subunit alpha-1 (mouse)
def: "An importin subunit alpha-1 that is encoded in the genome of mouse." [OMA:P52293, PRO:DNx]
comment: Category=organism-gene.
synonym: "Rch1" RELATED Gene-based [UniProtKB:P52293]
synonym: "Kpna2" RELATED Gene-based [UniProtKB:P52293]
synonym: "mKPNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "PTAC58 (mouse)" EXACT [UniProtKB:P52293]
synonym: "pendulin (mouse)" EXACT [UniProtKB:P52293]
synonym: "SRP1-alpha (mouse)" EXACT [UniProtKB:P52293]
synonym: "importin alpha P1 (mouse)" EXACT [UniProtKB:P52293]
synonym: "RAG cohort protein 1 (mouse)" EXACT [UniProtKB:P52293]
synonym: "karyopherin subunit alpha-2 (mouse)" EXACT [UniProtKB:P52293]
synonym: "pore targeting complex 58 kDa subunit (mouse)" EXACT [UniProtKB:P52293]
xref: UniProtKB:P52293
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009433 ! importin subunit alpha-1
relationship: has_gene_template MGI:103561 ! Kpna2 (mouse)

[Term]
id: PR:P52292
name: importin subunit alpha-1 (human)
def: "An importin subunit alpha-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P52292]
comment: Category=organism-gene.
synonym: "RCH1" RELATED Gene-based [UniProtKB:P52292]
synonym: "SRP1" RELATED Gene-based [UniProtKB:P52292]
synonym: "KPNA2" RELATED Gene-based [UniProtKB:P52292]
synonym: "hKPNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "SRP1-alpha (human)" EXACT [UniProtKB:P52292]
synonym: "RAG cohort protein 1 (human)" EXACT [UniProtKB:P52292]
synonym: "karyopherin subunit alpha-2 (human)" EXACT [UniProtKB:P52292]
xref: UniProtKB:P52292
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009433 ! importin subunit alpha-1
relationship: has_gene_template HGNC:6395 ! KPNA2 (human)

[Term]
id: PR:000048136
name: importin subunit alpha-1, initiator methionine removed form (human)
def: "An importin subunit alpha-1 (human) that has had the initiator methionine removed. UniProtKB:P52292, 2-529." [PRO:DNx, Reactome:R-HSA-205976, Reactome:R-HSA-206045]
comment: Category=organism-modification.
synonym: "PRO_0000120722" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hKPNA2/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P52292, 2-529" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-205976 "PR:000048136 located_in GO:0005829"
xref: Reactome:R-HSA-206045 "PR:000048136 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P52292 ! importin subunit alpha-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000039698
name: importin subunit alpha-1 isoform 1
def: "An importin subunit alpha-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52292-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "KPNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009433 ! importin subunit alpha-1

[Term]
id: PR:P52292-1
name: importin subunit alpha-1 isoform 1 (human)
def: "An importin subunit alpha-1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hKPNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52292-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039698 ! importin subunit alpha-1 isoform 1

[Term]
id: PR:000020397
name: importin subunit alpha-1, initiator methionine removed form
def: "An importin subunit alpha-1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "KPNA2/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000009433 ! importin subunit alpha-1
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P52293-1
name: importin subunit alpha-1 isoform 1 (mouse)
def: "An importin subunit alpha-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mKPNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52293-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039698 ! importin subunit alpha-1 isoform 1