[Term] id: PR:000009420 name: plasma kallikrein def: "A protein that is a translation product of the human KLKB1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "Pk" RELATED Gene-based [] synonym: "KLK3" RELATED Gene-based [] synonym: "KLKB1" EXACT PRO-short-label [PRO:DNx] synonym: "kininogenin" EXACT [] synonym: "fletcher factor" EXACT [] synonym: "plasma prekallikrein" EXACT [] xref: IUPHARobj:2379 is_a: PR:000000001 ! protein [Term] id: PR:000053134 name: plasma kallikrein N-glycosylated 4 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-396 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan structure is represented by GlyTouCan:G56903ZB. Example: UniProtKB:P03952-1, Asn-396, MOD:00160~GNO:G56903ZB." [GlyGen:P03952-1, PMID:24279413, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-396, MOD:00160~GNO:G56903ZB" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-396, MOD:00160~UniCarbKB:7425" NARROW [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G56903ZB ! G56903ZB relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053135 name: plasma kallikrein N-glycosylated 5 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-453 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P03952-1, Asn-453, MOD:00160~GNO:G00912UN." [GlyGen:P03952-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-453, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053136 name: plasma kallikrein N-glycosylated 6 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-453 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P03952-1, Asn-453, MOD:00160~GNO:G59626AS." [GlyGen:P03952-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-453, MOD:00160~GNO:G59626AS" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G59626AS ! G59626AS relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053137 name: plasma kallikrein N-glycosylated 7 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-494 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P03952-1, Asn-494, MOD:00160~GNO:G00912UN." [GlyGen:P03952-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-494, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053131 name: plasma kallikrein N-glycosylated 1 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-127 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P03952-1, Asn-127, MOD:00160~GNO:G00912UN." [GlyGen:P03952-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-127, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053132 name: plasma kallikrein N-glycosylated 2 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-127 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P03952-1, Asn-127, MOD:00160~GNO:G42358LZ." [GlyGen:P03952-1, PMID:24279413, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-127, MOD:00160~GNO:G42358LZ" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-127, MOD:00160~UniCarbKB:4923" NARROW [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G42358LZ ! G42358LZ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053133 name: plasma kallikrein N-glycosylated 3 (human) def: "A plasma kallikrein (human) that has been N-glycosylated at the residue equivalent to Asn-127 of the amino acid sequence represented by UniProtKB:P03952-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P03952-1, Asn-127, MOD:00160~GNO:G59626AS." [GlyGen:P03952-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hKLKB1/NGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952-1, Asn-127, MOD:00160~GNO:G59626AS" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P03952 ! plasma kallikrein (human) relationship: has_part GNO:G59626AS ! G59626AS relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P03952-1 name: plasma kallikrein isoform 1 (human) def: "A plasma kallikrein isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hKLKB1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P03952-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038642 ! plasma kallikrein isoform 1 [Term] id: PR:P03952 name: plasma kallikrein (human) def: "A plasma kallikrein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P03952] comment: Category=organism-gene. synonym: "KLK3" RELATED Gene-based [UniProtKB:P03952] synonym: "KLKB1" RELATED Gene-based [UniProtKB:P03952] synonym: "hKLKB1" EXACT PRO-short-label [PRO:DNx] synonym: "PKK (human)" EXACT [UniProtKB:P03952] synonym: "kininogenin (human)" EXACT [UniProtKB:P03952] synonym: "fletcher factor (human)" EXACT [UniProtKB:P03952] synonym: "plasma prekallikrein (human)" EXACT [UniProtKB:P03952] xref: UniProtKB:P03952 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000009420 ! plasma kallikrein relationship: has_gene_template HGNC:6371 ! KLKB1 (human) [Term] id: PR:000048133 name: plasma kallikrein, signal peptide removed form (human) def: "A plasma kallikrein (human) that has had the signal peptide removed. UniProtKB:P03952, 20-638." [PRO:DNx, Reactome:R-HSA-158385] comment: Category=organism-modification. synonym: "hKLKB1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P03952, 20-638" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-158385 "PR:000048133 located_in GO:0005886" intersection_of: PR:P03952 ! plasma kallikrein (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens