[Term]
id: PR:Q556J2
name: 3-ketodihydrosphingosine reductase (Dictyostelium discoideum)
def: "A 3-ketodihydrosphingosine reductase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q556J2, PANTHER:PTHR24320:SF40, PRO:DNx]
comment: Category=organism-gene.
synonym: "ksrA-1" RELATED Gene-based [UniProtKB:Q556J2]
synonym: "ksrA-2" RELATED Gene-based [UniProtKB:Q556J2]
synonym: "Dicty-KDSR" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0272883" RELATED Gene-based [UniProtKB:Q556J2]
synonym: "DDB_G0274015" RELATED Gene-based [UniProtKB:Q556J2]
synonym: "KDS reductase (Dictyostelium discoideum)" EXACT [UniProtKB:Q556J2]
synonym: "3-dehydrosphinganine reductase (Dictyostelium discoideum)" EXACT [UniProtKB:Q556J2]
xref: UniProtKB:Q556J2
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000009276 ! 3-ketodihydrosphingosine reductase
relationship: has_gene_template dictyBase:DDB_G0272883 ! ksrA-1 (Dictyostelium discoideum)
relationship: has_gene_template dictyBase:DDB_G0274015 ! ksrA-2 (Dictyostelium discoideum)

[Term]
id: PR:000040297
name: 3-ketodihydrosphingosine reductase isoform 1
def: "A 3-ketodihydrosphingosine reductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06136-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "KDSR/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009276 ! 3-ketodihydrosphingosine reductase

[Term]
id: PR:000048098
name: 3-ketodihydrosphingosine reductase, signal peptide removed form (human)
def: "A 3-ketodihydrosphingosine reductase (human) that has had the signal peptide removed. UniProtKB:Q06136, 26-332." [PRO:DNx, Reactome:R-HSA-428134]
comment: Category=organism-modification.
synonym: "hKDSR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000031982" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q06136, 26-332" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-428134 "PR:000048098 located_in GO:0005789"
intersection_of: PR:Q06136 ! 3-ketodihydrosphingosine reductase (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06136-2
name: 3-ketodihydrosphingosine reductase isoform h2 (human)
def: "A 3-ketodihydrosphingosine reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06136-2." [PRO:DNx, UniProtKB:Q06136]
comment: Category=organism-sequence.
synonym: "hKDSR/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06136-2
is_a: PR:Q06136 ! 3-ketodihydrosphingosine reductase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000009276
name: 3-ketodihydrosphingosine reductase
def: "A protein that is a translation product of the human KDSR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FVT1" RELATED Gene-based []
synonym: "KDSR" EXACT PRO-short-label [PRO:DNx]
synonym: "FVT-1" EXACT []
synonym: "SDR35C1" RELATED Gene-based []
synonym: "KDS reductase" EXACT []
synonym: "3-dehydrosphinganine reductase" EXACT []
synonym: "follicular variant translocation protein 1" EXACT []
synonym: "follicular variant translocation protein 1 homolog" EXACT []
xref: IUPHARobj:2463
is_a: PR:000000001 ! protein

[Term]
id: PR:Q6GV12
name: 3-ketodihydrosphingosine reductase (mouse)
def: "A 3-ketodihydrosphingosine reductase that is encoded in the genome of mouse." [OMA:Q6GV12, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fvt1" RELATED Gene-based [UniProtKB:Q6GV12]
synonym: "Kdsr" RELATED Gene-based [UniProtKB:Q6GV12]
synonym: "mKDSR" EXACT PRO-short-label [PRO:DNx]
synonym: "FVT-1 (mouse)" EXACT [UniProtKB:Q6GV12]
synonym: "KDS reductase (mouse)" EXACT [UniProtKB:Q6GV12]
synonym: "3-dehydrosphinganine reductase (mouse)" EXACT [UniProtKB:Q6GV12]
synonym: "follicular variant translocation protein 1 homolog (mouse)" EXACT [UniProtKB:Q6GV12]
xref: UniProtKB:Q6GV12
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009276 ! 3-ketodihydrosphingosine reductase
relationship: has_gene_template MGI:1918000 ! Kdsr (mouse)

[Term]
id: PR:Q6GV12-1
name: 3-ketodihydrosphingosine reductase isoform 1 (mouse)
def: "A 3-ketodihydrosphingosine reductase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mKDSR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6GV12-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040297 ! 3-ketodihydrosphingosine reductase isoform 1

[Term]
id: PR:Q06136
name: 3-ketodihydrosphingosine reductase (human)
def: "A 3-ketodihydrosphingosine reductase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06136]
comment: Category=organism-gene.
synonym: "FVT1" RELATED Gene-based [UniProtKB:Q06136]
synonym: "KDSR" RELATED Gene-based [UniProtKB:Q06136]
synonym: "hKDSR" EXACT PRO-short-label [PRO:DNx]
synonym: "SDR35C1" RELATED Gene-based [UniProtKB:Q06136]
synonym: "FVT-1 (human)" EXACT [UniProtKB:Q06136]
synonym: "KDS reductase (human)" EXACT [UniProtKB:Q06136]
synonym: "3-dehydrosphinganine reductase (human)" EXACT [UniProtKB:Q06136]
synonym: "follicular variant translocation protein 1 (human)" EXACT [UniProtKB:Q06136]
synonym: "short chain dehydrogenase/reductase family 35C member 1 (human)" EXACT [UniProtKB:Q06136]
xref: UniProtKB:Q06136
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009276 ! 3-ketodihydrosphingosine reductase
relationship: has_gene_template HGNC:4021 ! KDSR (human)

[Term]
id: PR:Q06136-1
name: 3-ketodihydrosphingosine reductase isoform 1 (human)
def: "A 3-ketodihydrosphingosine reductase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hKDSR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06136-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040297 ! 3-ketodihydrosphingosine reductase isoform 1