[Term]
id: PR:000048084
name: tyrosine-protein kinase JAK1 phosphotyrosine form (human)
def: "A tyrosine-protein kinase JAK1 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P23458, MOD:00048." [PRO:DNx, Reactome:R-HSA-451921]
comment: Category=organism-modification.
synonym: "hJAK1/PhosTyr+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P23458, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-451921 "PR:000048084 located_in GO:0005829"
intersection_of: has_part MOD:00048 ! O4'-phospho-L-tyrosine
intersection_of: PR:P23458 ! tyrosine-protein kinase JAK1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P23458
name: tyrosine-protein kinase JAK1 (human)
def: "A tyrosine-protein kinase JAK1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P23458]
comment: Category=organism-gene.
synonym: "JAK1" RELATED Gene-based [UniProtKB:P23458]
synonym: "JAK1A" RELATED Gene-based [UniProtKB:P23458]
synonym: "JAK1B" RELATED Gene-based [UniProtKB:P23458]
synonym: "hJAK1" EXACT PRO-short-label [PRO:DNx]
synonym: "JAK-1 (human)" EXACT [UniProtKB:P23458]
synonym: "Janus kinase 1 (human)" EXACT [UniProtKB:P23458]
xref: Reactome:R-HSA-451898 "PR:P23458 located_in GO:0005829"
xref: Reactome:R-HSA-8983168 "PR:P23458 located_in GO:0005768"
xref: DTO:03100196
xref: UniProtKB:P23458
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009196 ! tyrosine-protein kinase JAK1
relationship: has_gene_template HGNC:6190 ! JAK1 (human)

[Term]
id: PR:000009196
name: tyrosine-protein kinase JAK1
def: "A Janus kinase that is a translation product of the human JAK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "JAK1" EXACT PRO-short-label [PRO:DNx]
synonym: "JAK-1" EXACT []
synonym: "JAK1A" RELATED Gene-based []
synonym: "JAK1B" RELATED Gene-based []
synonym: "Janus kinase 1" EXACT []
xref: IUPHARobj:2047
is_a: PR:000025748 ! Janus kinase

[Term]
id: PR:000048083
name: tyrosine-protein kinase JAK1 phosphorylated 1 (human)
def: "A tyrosine-protein kinase JAK1 (human) that has been post-translationally modified to include phosphotyrosine at position 1034 of the amino acid sequence represented by UniProtKB:P23458. UniProtKB:P23458, Tyr-1034, MOD:00048." [PRO:DNx, Reactome:R-HSA-1112543]
comment: Category=organism-modification.
synonym: "hJAK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P23458, Tyr-1034, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1112543 "PR:000048083 located_in GO:0005829"
is_a: PR:P23458 ! tyrosine-protein kinase JAK1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens