[Term]
id: PR:Q14643-7
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h7 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-7." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SI-SIII-SIIA (human)" BROAD [UniProtKB:Q14643]
xref: UniProtKB:Q14643-7
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643-6
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h6 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-6." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SISIIISIIA (human)" EXACT [UniProtKB:Q14643]
xref: UniProtKB:Q14643-6
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643-5
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h5 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-5." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SI-SIII-SIIAC (human)" EXACT [UniProtKB:Q14643]
xref: UniProtKB:Q14643-5
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643-4
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h4 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-4." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SI-SIII-SII (human)" EXACT [UniProtKB:Q14643]
xref: UniProtKB:Q14643-4
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643-3
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h3 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-3." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SISIII-SII (human)" EXACT [UniProtKB:Q14643]
xref: UniProtKB:Q14643-3
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643-2
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h2 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-2." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SI-SIIISIIAC (human)" EXACT [UniProtKB:Q14643]
xref: UniProtKB:Q14643-2
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643-1
name: inositol 1,4,5-trisphosphate receptor type 1 isoform 1 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "SISIIISIIAC (human)" EXACT []
synonym: "IP3 receptor type 1 isoform SISIIISIIAC (human)" EXACT []
xref: UniProtKB:Q14643-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026789 ! inositol 1,4,5-trisphosphate receptor type 1 isoform 1

[Term]
id: PR:000009158
name: inositol 1,4,5-trisphosphate receptor type 1
def: "An IP(3) receptor that is a translation product of the human ITPR1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Pcd6" RELATED Gene-based []
synonym: "Pcp1" RELATED Gene-based []
synonym: "ITPR1" EXACT PRO-short-label [PRO:DNx]
synonym: "IP3R 1" EXACT []
synonym: "Insp3r" RELATED Gene-based []
synonym: "INSP3R1" RELATED Gene-based []
synonym: "InsP3R1" EXACT []
synonym: "protein PCD-6" EXACT []
synonym: "type 1 InsP3 receptor" EXACT []
synonym: "IP3 receptor isoform 1" EXACT []
synonym: "Purkinje cell protein 1" EXACT []
synonym: "type 1 inositol 1,4,5-trisphosphate receptor" EXACT []
synonym: "inositol 1,4,5-trisphosphate-binding protein P400" EXACT []
xref: IUPHARobj:743
is_a: PR:000044667 ! IP(3) receptor

[Term]
id: PR:Q14643-8
name: inositol 1,4,5-trisphosphate receptor type 1 isoform h8 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14643-8." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-sequence.
synonym: "hITPR1/iso:h8" EXACT PRO-short-label [PRO:DNx]
synonym: "inositol 1,4,5-trisphosphate receptor type 1 isoform SI-SIII-SIIA (human)" BROAD [UniProtKB:Q14643]
xref: UniProtKB:Q14643-8
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045928
name: inositol 1,4,5-trisphosphate receptor type 1 phosphorylated 1 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 (human) that has been phosphorylated at the position equivalent to Tyr-353 of the amino acid sequence represented by UniProtKB:Q14643-1. Example: UniProtKB:Q14643-1, Tyr-353, MOD:00048." [PMID:14761954, PMID:18056410, iPTMnet:Q14643]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14761954, PMID:18056410). Status=unreviewed.
synonym: "hITPR1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q14643-1, Tyr-353, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q14643 ! inositol 1,4,5-trisphosphate receptor type 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14643
name: inositol 1,4,5-trisphosphate receptor type 1 (human)
def: "An inositol 1,4,5-trisphosphate receptor type 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14643]
comment: Category=organism-gene.
synonym: "ITPR1" RELATED Gene-based [UniProtKB:Q14643]
synonym: "hITPR1" EXACT PRO-short-label [PRO:DNx]
synonym: "INSP3R1" RELATED Gene-based [UniProtKB:Q14643]
synonym: "IP3R 1 (human)" EXACT [UniProtKB:Q14643]
synonym: "type 1 InsP3 receptor (human)" EXACT [UniProtKB:Q14643]
synonym: "IP3 receptor isoform 1 (human)" EXACT [UniProtKB:Q14643]
synonym: "type 1 inositol 1,4,5-trisphosphate receptor (human)" EXACT [UniProtKB:Q14643]
xref: Reactome:R-HSA-3006433 "PR:Q14643 located_in GO:0005789"
xref: Reactome:R-HSA-3325593 "PR:Q14643 located_in GO:0031095"
xref: DTO:01100165
xref: UniProtKB:Q14643
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009158 ! inositol 1,4,5-trisphosphate receptor type 1
relationship: has_gene_template HGNC:6180 ! ITPR1 (human)