[Term]
id: PR:000020266
name: insulin-like growth factor II, signal peptide removed form
def: "An insulin-like growth factor II that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "IGF2/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008942 ! insulin-like growth factor II
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000020267
name: insulin-like growth factor II proteolytic cleavage product
def: "An insulin-like growth factor II that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "IGF2/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000008942 ! insulin-like growth factor II

[Term]
id: PR:000051763
name: insulin-like growth factor II O-glycosylated 4 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-96 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01344-1, Thr-96, MOD:00005~GNO:G58001LT." [GlyGen:P01344-1, PMID:22171320, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-96, MOD:00005~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G58001LT ! G58001LT
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051762
name: insulin-like growth factor II O-glycosylated 3 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-96 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01344-1, Thr-96, MOD:00005~GNO:G53434XO." [GlyGen:P01344-1, PMID:22171320, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-96, MOD:00005~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G53434XO ! G53434XO
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051761
name: insulin-like growth factor II O-glycosylated 2 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-96 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01344-1, Thr-96, MOD:00005~GNO:G43417UB." [GlyGen:P01344-1, PMID:22171320, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-96, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051760
name: insulin-like growth factor II O-glycosylated 1 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-163 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01344-1, Thr-163, MOD:00005~GNO:G43417UB." [GlyGen:P01344-1, PMID:22171320, PMID:23234360, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-163, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051767
name: insulin-like growth factor II O-glycosylated 8 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-99 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G58001LT." [GlyGen:P01344-1, PMID:22171320, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G58001LT ! G58001LT
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051766
name: insulin-like growth factor II O-glycosylated 7 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-99 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G53434XO." [GlyGen:P01344-1, PMID:22171320, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G53434XO ! G53434XO
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051765
name: insulin-like growth factor II O-glycosylated 6 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-99 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G43417UB." [GlyGen:P01344-1, PMID:22171320, PMID:23234360, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051764
name: insulin-like growth factor II O-glycosylated 5 (human)
def: "An insulin-like growth factor II (human) that has been O-glycosylated at the residue equivalent to Thr-99 of the amino acid sequence represented by UniProtKB:P01344-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G29068FM." [GlyGen:P01344-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGF2/OGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01344-1, Thr-99, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P09535-2
name: insulin-like growth factor II isoform m2 (mouse)
def: "An insulin-like growth factor II (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09535-2." [PRO:DNx, UniProtKB:P09535]
comment: Category=organism-sequence.
synonym: "mIGF2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09535-2
is_a: PR:P09535 ! insulin-like growth factor II (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P09535-1
name: insulin-like growth factor II isoform 1 (mouse)
def: "An insulin-like growth factor II isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mIGF2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09535-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038786 ! insulin-like growth factor II isoform 1

[Term]
id: PR:P01344
name: insulin-like growth factor II (human)
def: "An insulin-like growth factor II that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01344]
comment: Category=organism-gene.
synonym: "IGF2" RELATED Gene-based [UniProtKB:P01344]
synonym: "hIGF2" EXACT PRO-short-label [PRO:DNx]
synonym: "PP1446" RELATED Gene-based [UniProtKB:P01344]
synonym: "IGF-II (human)" EXACT [UniProtKB:P01344]
synonym: "somatomedin-A (human)" EXACT [UniProtKB:P01344]
synonym: "T3M-11-derived growth factor (human)" EXACT [UniProtKB:P01344]
xref: UniProtKB:P01344
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008942 ! insulin-like growth factor II
relationship: has_gene_template HGNC:5466 ! IGF2 (human)

[Term]
id: PR:P01346
name: insulin-like growth factor II (rat)
def: "An insulin-like growth factor II that is encoded in the genome of rat." [OMA:P01346, PRO:DNx]
comment: Category=organism-gene.
synonym: "Igf2" RELATED Gene-based [UniProtKB:P01346]
synonym: "Igf-2" RELATED Gene-based [UniProtKB:P01346]
synonym: "rIGF2" EXACT PRO-short-label [PRO:DNx]
synonym: "MSA (rat)" EXACT [UniProtKB:P01346]
synonym: "IGF-II (rat)" EXACT [UniProtKB:P01346]
synonym: "multiplication-stimulating activity (rat)" EXACT [UniProtKB:P01346]
synonym: "multiplication-stimulating polypeptide (rat)" EXACT [UniProtKB:P01346]
xref: UniProtKB:P01346
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008942 ! insulin-like growth factor II
relationship: has_gene_template RGD:2870 ! Igf2 (rat)

[Term]
id: PR:P33717
name: insulin-like growth factor II (chicken)
def: "An insulin-like growth factor II that is encoded in the genome of chicken." [OMA:P33717, PANTHER:PTHR11454:SF10, PRO:DNx]
comment: Category=organism-gene.
synonym: "IGF2" RELATED Gene-based [UniProtKB:P33717]
synonym: "chick-IGF2" EXACT PRO-short-label [PRO:DNx]
synonym: "IGF-II (chicken)" EXACT [UniProtKB:P33717]
xref: UniProtKB:P33717
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000008942 ! insulin-like growth factor II
relationship: has_gene_template NCBIGene:395097 ! IGF2 (chicken)

[Term]
id: PR:000008942
name: insulin-like growth factor II
def: "A protein that is a translation product of the human IGF2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "IGF2" EXACT PRO-short-label [PRO:DNx]
synonym: "Igf-2" RELATED Gene-based []
synonym: "IGF-II" EXACT []
synonym: "PP1446" RELATED Gene-based []
synonym: "somatomedin-A" EXACT []
synonym: "multiplication-stimulating polypeptide" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P01346-1
name: insulin-like growth factor II isoform 1 (rat)
def: "An insulin-like growth factor II isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rIGF2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01346-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038786 ! insulin-like growth factor II isoform 1

[Term]
id: PR:000038786
name: insulin-like growth factor II isoform 1
def: "An insulin-like growth factor II that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09535-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "IGF2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008942 ! insulin-like growth factor II

[Term]
id: PR:P01344-1
name: insulin-like growth factor II isoform h1 (human)
def: "An insulin-like growth factor II (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01344-1." [PRO:DNx, UniProtKB:P01344]
comment: Category=organism-sequence.
synonym: "hIGF2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01344-1
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01344-2
name: insulin-like growth factor II isoform h2 (human)
def: "An insulin-like growth factor II (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01344-2." [PRO:DNx, UniProtKB:P01344]
comment: Category=organism-sequence.
synonym: "hIGF2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01344-2
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01344-3
name: insulin-like growth factor II isoform h3 (human)
def: "An insulin-like growth factor II (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01344-3." [PRO:DNx, UniProtKB:P01344]
comment: Category=organism-sequence.
synonym: "hIGF2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01344-3
is_a: PR:P01344 ! insulin-like growth factor II (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P09535
name: insulin-like growth factor II (mouse)
def: "An insulin-like growth factor II that is encoded in the genome of mouse." [OMA:P09535, PRO:DNx]
comment: Category=organism-gene.
synonym: "Igf2" RELATED Gene-based [UniProtKB:P09535]
synonym: "Igf-2" RELATED Gene-based [UniProtKB:P09535]
synonym: "mIGF2" EXACT PRO-short-label [PRO:DNx]
synonym: "IGF-II (mouse)" EXACT [UniProtKB:P09535]
synonym: "multiplication-stimulating polypeptide (mouse)" EXACT [UniProtKB:P09535]
xref: UniProtKB:P09535
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008942 ! insulin-like growth factor II
relationship: has_gene_template MGI:96434 ! Igf2 (mouse)