[Term]
id: PR:O14254
name: probable isocitrate dehydrogenase [NADP], mitochondrial (Schizosaccharomyces pombe 972h-)
def: "An isocitrate dehydrogenase [NADP], mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR11822:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "idp1" RELATED Gene-based [UniProtKB:O14254]
synonym: "SPAC6G10.08" RELATED Gene-based [UniProtKB:O14254]
synonym: "Spom972h-idp1" EXACT PRO-short-label [PRO:DNx]
synonym: "IDH (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14254]
synonym: "IDP (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14254]
synonym: "NADP(+)-specific ICDH (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14254]
synonym: "oxalosuccinate decarboxylase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14254]
xref: UniProtKB:O14254
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000008888 ! isocitrate dehydrogenase [NADP], mitochondrial
relationship: has_gene_template PomBase:SPAC6G10.08 ! idp1 (Schizosaccharomyces pombe)

[Term]
id: PR:000039559
name: isocitrate dehydrogenase [NADP], mitochondrial isoform 1
def: "An isocitrate dehydrogenase [NADP], mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48735-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "IDH2nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008888 ! isocitrate dehydrogenase [NADP], mitochondrial

[Term]
id: PR:000008888
name: isocitrate dehydrogenase [NADP], mitochondrial
def: "A protein that is a translation product of the human IDH2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "IDH" BROAD [PRO:DNx]
synonym: "IDP" BROAD [PRO:DNx]
synonym: "IDH2" RELATED Gene-based []
synonym: "ICD-M" EXACT []
synonym: "IDH2nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "NADP(+)-specific ICDH" BROAD [PRO:DNx]
synonym: "oxalosuccinate decarboxylase" BROAD [PRO:DNx]
xref: IUPHARobj:2885
is_a: PR:000000001 ! protein

[Term]
id: PR:P56574-1
name: isocitrate dehydrogenase [NADP], mitochondrial isoform 1 (rat)
def: "An isocitrate dehydrogenase [NADP], mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rIDH2nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P56574-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039559 ! isocitrate dehydrogenase [NADP], mitochondrial isoform 1

[Term]
id: PR:P48735
name: isocitrate dehydrogenase [NADP], mitochondrial (human)
def: "An isocitrate dehydrogenase [NADP], mitochondrial that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "IDH2" RELATED Gene-based [UniProtKB:P48735]
synonym: "hIDH2nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "IDH (human)" BROAD [UniProtKB:P48735]
synonym: "IDP (human)" BROAD [UniProtKB:P48735]
synonym: "ICD-M (human)" EXACT [UniProtKB:P48735]
synonym: "NADP(+)-specific ICDH (human)" BROAD [UniProtKB:P48735]
synonym: "oxalosuccinate decarboxylase (human)" BROAD [UniProtKB:P48735]
xref: UniProtKB:P48735
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008888 ! isocitrate dehydrogenase [NADP], mitochondrial
relationship: has_gene_template HGNC:5383 ! IDH2 (human)

[Term]
id: PR:P54071-1
name: isocitrate dehydrogenase [NADP], mitochondrial isoform 1 (mouse)
def: "An isocitrate dehydrogenase [NADP], mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mIDH2nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P54071-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039559 ! isocitrate dehydrogenase [NADP], mitochondrial isoform 1

[Term]
id: PR:P48735-2
name: isocitrate dehydrogenase [NADP], mitochondrial isoform h2 (human)
def: "An isocitrate dehydrogenase [NADP], mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48735-2." [PRO:DNx, UniProtKB:P48735]
comment: Category=organism-sequence.
synonym: "hIDH2nadp/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48735-2
is_a: PR:P48735 ! isocitrate dehydrogenase [NADP], mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48735-1
name: isocitrate dehydrogenase [NADP], mitochondrial isoform 1 (human)
def: "An isocitrate dehydrogenase [NADP], mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hIDH2nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48735-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039559 ! isocitrate dehydrogenase [NADP], mitochondrial isoform 1

[Term]
id: PR:P54071
name: isocitrate dehydrogenase [NADP], mitochondrial (mouse)
def: "An isocitrate dehydrogenase [NADP], mitochondrial that is encoded in the genome of mouse." [OMA:P54071, PRO:DNx]
comment: Category=organism-gene.
synonym: "Idh2" RELATED Gene-based [UniProtKB:P54071]
synonym: "mIDH2nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "IDH (mouse)" RELATED [UniProtKB:P54071]
synonym: "IDP (mouse)" RELATED [UniProtKB:P54071]
synonym: "ICD-M (mouse)" EXACT [UniProtKB:P54071]
synonym: "NADP(+)-specific ICDH (mouse)" RELATED [UniProtKB:P54071]
synonym: "oxalosuccinate decarboxylase (mouse)" RELATED [UniProtKB:P54071]
xref: UniProtKB:P54071
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008888 ! isocitrate dehydrogenase [NADP], mitochondrial
relationship: has_gene_template MGI:96414 ! Idh2 (mouse)

[Term]
id: PR:P56574
name: isocitrate dehydrogenase [NADP], mitochondrial (rat)
def: "An isocitrate dehydrogenase [NADP], mitochondrial that is encoded in the genome of rat." [OMA:P56574, PANTHER:PTHR11822:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Idh2" RELATED Gene-based [UniProtKB:P56574]
synonym: "IDH (rat)" RELATED [UniProtKB:P56574]
synonym: "IDP (rat)" RELATED [UniProtKB:P56574]
synonym: "rIDH2nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "ICD-M (rat)" EXACT [UniProtKB:P56574]
synonym: "NADP(+)-specific ICDH (rat)" RELATED [UniProtKB:P56574]
synonym: "oxalosuccinate decarboxylase (rat)" RELATED [UniProtKB:P56574]
xref: UniProtKB:P56574
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008888 ! isocitrate dehydrogenase [NADP], mitochondrial
relationship: has_gene_template RGD:1597139 ! Idh2 (rat)

[Term]
id: PR:000047942
name: isocitrate dehydrogenase [NADP], mitochondrial, transit peptide removed form (human)
def: "An isocitrate dehydrogenase [NADP], mitochondrial (human) that has had the transit peptide removed. UniProtKB:P48735, 40-452." [PRO:DNx, Reactome:R-HSA-450988]
comment: Category=organism-modification.
synonym: "PRO_0000014420" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hIDH2nadp/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48735, 40-452" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-450988 "PR:000047942 located_in GO:0005759"
intersection_of: PR:P48735 ! isocitrate dehydrogenase [NADP], mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens