[Term]
id: PR:000008839
name: serine protease HTRA2, mitochondrial
def: "A protein that is a translation product of the human HTRA2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "OMI" RELATED Gene-based []
synonym: "HTRA2" EXACT PRO-short-label [PRO:DNx]
synonym: "HtrA2" EXACT []
synonym: "PRSS25" RELATED Gene-based []
synonym: "serine protease 25" EXACT []
synonym: "serine proteinase OMI" EXACT []
synonym: "Omi stress-regulated endoprotease" EXACT []
synonym: "high temperature requirement protein A2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000045587
name: serine protease HTRA2, mitochondrial phosphorylated 1 (human)
def: "A serine protease HTRA2, mitochondrial (human) that has been phosphorylated at the position equivalent to Ser-212 of the amino acid sequence represented by UniProtKB:O43464-1. Example: UniProtKB:O43464-1, Ser-212, MOD:00046." [PMID:17311912, iPTMnet:O43464]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17311912). Status=unreviewed.
synonym: "hHTRA2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43464-1, Ser-212, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O43464 ! serine protease HTRA2, mitochondrial (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43464-4
name: serine protease HTRA2, mitochondrial isoform h4 (human)
def: "A serine protease HTRA2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43464-4." [PRO:DNx, UniProtKB:O43464]
comment: Category=organism-sequence.
synonym: "hHTRA2/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "serine protease HTRA2, mitochondrial isoform p4 (human)" EXACT [UniProtKB:O43464]
xref: UniProtKB:O43464-4
is_a: PR:O43464 ! serine protease HTRA2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43464-2
name: serine protease HTRA2, mitochondrial isoform h2 (human)
def: "A serine protease HTRA2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43464-2." [PRO:DNx, UniProtKB:O43464]
comment: Category=organism-sequence.
synonym: "hHTRA2/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "serine protease HTRA2, mitochondrial isoform D-Omi (human)" EXACT [UniProtKB:O43464]
xref: UniProtKB:O43464-2
is_a: PR:O43464 ! serine protease HTRA2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43464-3
name: serine protease HTRA2, mitochondrial isoform h3 (human)
def: "A serine protease HTRA2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43464-3." [PRO:DNx, UniProtKB:O43464]
comment: Category=organism-sequence.
synonym: "hHTRA2/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "serine protease HTRA2, mitochondrial isoform p7 (human)" EXACT [UniProtKB:O43464]
xref: UniProtKB:O43464-3
is_a: PR:O43464 ! serine protease HTRA2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43464-1
name: serine protease HTRA2, mitochondrial isoform 1 (human)
def: "A serine protease HTRA2, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHTRA2/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "serine protease HTRA2, mitochondrial isoform 13B (human)" EXACT [UniProtKB:O43464]
xref: UniProtKB:O43464-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038142 ! serine protease HTRA2, mitochondrial isoform 1

[Term]
id: PR:O43464
name: serine protease HTRA2, mitochondrial (human)
def: "A serine protease HTRA2, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43464]
comment: Category=organism-gene.
synonym: "OMI" RELATED Gene-based [UniProtKB:O43464]
synonym: "HTRA2" RELATED Gene-based [UniProtKB:O43464]
synonym: "PRSS25" RELATED Gene-based [UniProtKB:O43464]
synonym: "hHTRA2" EXACT PRO-short-label [PRO:DNx]
synonym: "HtrA2 (human)" EXACT [UniProtKB:O43464]
synonym: "serine protease 25 (human)" EXACT [UniProtKB:O43464]
synonym: "serine proteinase OMI (human)" EXACT [UniProtKB:O43464]
synonym: "Omi stress-regulated endoprotease (human)" EXACT [UniProtKB:O43464]
synonym: "high temperature requirement protein A2 (human)" EXACT [UniProtKB:O43464]
xref: UniProtKB:O43464
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008839 ! serine protease HTRA2, mitochondrial
relationship: has_gene_template HGNC:14348 ! HTRA2 (human)