[Term]
id: PR:P11021-1
name: endoplasmic reticulum chaperone BiP isoform 1 (human)
def: "An endoplasmic reticulum chaperone BiP isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHSPA5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P11021-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038824 ! endoplasmic reticulum chaperone BiP isoform 1

[Term]
id: PR:000008810
name: endoplasmic reticulum chaperone BiP
def: "An HSPA protein that is a translation product of the human HSPA5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BiP" EXACT []
synonym: "GRP78" RELATED Gene-based []
synonym: "HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "GRP-78" EXACT []
synonym: "HSP70 family protein 5" EXACT []
synonym: "heat shock 70 kDa protein 5" EXACT []
synonym: "binding-immunoglobulin protein" EXACT []
synonym: "78 kDa glucose-regulated protein" EXACT []
synonym: "heat shock protein family A member 5" EXACT []
synonym: "heat shock protein 70 family protein 5" EXACT []
synonym: "immunoglobulin heavy chain-binding protein" EXACT []
synonym: "endoplasmic reticulum lumenal Ca(2+)-binding protein grp78" EXACT []
is_a: PR:000003426 ! HSPA protein

[Term]
id: PR:P11021
name: endoplasmic reticulum chaperone BiP (human)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-gene.
synonym: "GRP78" RELATED Gene-based [UniProtKB:P11021]
synonym: "HSPA5" RELATED Gene-based [UniProtKB:P11021]
synonym: "hHSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (human)" EXACT [UniProtKB:P11021]
synonym: "GRP-78 (human)" EXACT [UniProtKB:P11021]
synonym: "HSP70 family protein 5 (human)" EXACT [UniProtKB:P11021]
synonym: "binding-immunoglobulin protein (human)" EXACT [UniProtKB:P11021]
synonym: "78 kDa glucose-regulated protein (human)" EXACT [UniProtKB:P11021]
synonym: "heat shock protein family A member 5 (human)" EXACT [UniProtKB:P11021]
synonym: "heat shock protein 70 family protein 5 (human)" EXACT [UniProtKB:P11021]
synonym: "immunoglobulin heavy chain-binding protein (human)" EXACT [UniProtKB:P11021]
xref: UniProtKB:P11021
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template HGNC:5238 ! HSPA5 (human)

[Term]
id: PR:000047915
name: endoplasmic reticulum chaperone BiP, signal peptide removed form (human)
def: "An endoplasmic reticulum chaperone BiP (human) that has had the signal peptide removed. UniProtKB:P11021, 19-654." [PRO:DNx, Reactome:R-HSA-351315, Reactome:R-HSA-351322, Reactome:R-HSA-387190, Reactome:R-HSA-5252042, Reactome:R-HSA-5252115, Reactome:R-HSA-985498]
comment: Category=organism-modification.
synonym: "PRO_0000013566" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHSPA5/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P11021, 19-654" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-351315 "PR:000047915 located_in GO:0005789"
xref: Reactome:R-HSA-351322 "PR:000047915 located_in GO:0005576"
xref: Reactome:R-HSA-387190 "PR:000047915 located_in GO:0005788"
xref: Reactome:R-HSA-985498 "PR:000047915 located_in GO:0071556"
xref: Reactome:R-HSA-5252042 "PR:000047915 located_in GO:0005654"
xref: Reactome:R-HSA-5252115 "PR:000047915 located_in GO:0005829"
xref: TDR:1424
intersection_of: PR:P11021 ! endoplasmic reticulum chaperone BiP (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens