[Term]
id: PR:P51660
name: peroxisomal multifunctional enzyme type 2 (mouse)
def: "A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of mouse." [OMA:P51660, PRO:DNx]
comment: Category=organism-gene.
synonym: "Edh17b4" RELATED Gene-based [UniProtKB:P51660]
synonym: "Hsd17b4" RELATED Gene-based [UniProtKB:P51660]
synonym: "mHSD17B4" EXACT PRO-short-label [PRO:DNx]
synonym: "DBP (mouse)" EXACT [UniProtKB:P51660]
synonym: "MFE-2 (mouse)" EXACT [UniProtKB:P51660]
synonym: "MFP-2 (mouse)" EXACT [UniProtKB:P51660]
synonym: "17-beta-HSD 4 (mouse)" EXACT [UniProtKB:P51660]
synonym: "D-bifunctional protein (mouse)" EXACT [UniProtKB:P51660]
synonym: "multifunctional protein 2 (mouse)" EXACT [UniProtKB:P51660]
synonym: "17-beta-hydroxysteroid dehydrogenase 4 (mouse)" EXACT [UniProtKB:P51660]
xref: UniProtKB:P51660
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
relationship: has_gene_template MGI:105089 ! Hsd17b4 (mouse)

[Term]
id: PR:P97852
name: peroxisomal multifunctional enzyme type 2 (rat)
def: "A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of rat." [OMA:P97852, PANTHER:PTHR24316:SF50, PRO:DNx]
comment: Category=organism-gene.
synonym: "Edh17b4" RELATED Gene-based [UniProtKB:P97852]
synonym: "Hsd17b4" RELATED Gene-based [UniProtKB:P97852]
synonym: "rHSD17B4" EXACT PRO-short-label [PRO:DNx]
synonym: "DBP (rat)" RELATED [UniProtKB:P97852]
synonym: "MFE-2 (rat)" EXACT [UniProtKB:P97852]
synonym: "MFP-2 (rat)" EXACT [UniProtKB:P97852]
synonym: "17-beta-HSD 4 (rat)" EXACT [UniProtKB:P97852]
synonym: "D-bifunctional protein (rat)" EXACT [UniProtKB:P97852]
synonym: "multifunctional protein 2 (rat)" EXACT [UniProtKB:P97852]
synonym: "17-beta-hydroxysteroid dehydrogenase 4 (rat)" EXACT [UniProtKB:P97852]
xref: UniProtKB:P97852
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
relationship: has_gene_template RGD:621806 ! Hsd17b4 (rat)

[Term]
id: PR:Q21481
name: M03A8.1 (worm)
def: "A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of worm." [PANTHER:PTHR24316:SF50, PRO:DNx]
comment: Category=organism-gene.
synonym: "CELE_M03A8.1" RELATED Gene-based [UniProtKB:Q21481]
synonym: "HSD17B4 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q21481
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
relationship: has_gene_template WormBase:WBGene00000991 ! dhs-28 (worm)

[Term]
id: PR:P51659
name: peroxisomal multifunctional enzyme type 2 (human)
def: "A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P51659]
comment: Category=organism-gene.
synonym: "SDR8C1" RELATED Gene-based [UniProtKB:P51659]
synonym: "EDH17B4" RELATED Gene-based [UniProtKB:P51659]
synonym: "HSD17B4" RELATED Gene-based [UniProtKB:P51659]
synonym: "hHSD17B4" EXACT PRO-short-label [PRO:DNx]
synonym: "DBP (human)" BROAD [UniProtKB:P51659]
synonym: "MFE-2 (human)" EXACT [UniProtKB:P51659]
synonym: "MFP-2 (human)" EXACT [UniProtKB:P51659]
synonym: "17-beta-HSD 4 (human)" EXACT [UniProtKB:P51659]
synonym: "D-bifunctional protein (human)" EXACT [UniProtKB:P51659]
synonym: "multifunctional protein 2 (human)" EXACT [UniProtKB:P51659]
synonym: "17-beta-hydroxysteroid dehydrogenase 4 (human)" EXACT [UniProtKB:P51659]
synonym: "short chain dehydrogenase/reductase family 8C member 1 (human)" EXACT [UniProtKB:P51659]
xref: Reactome:R-HSA-192322 "PR:P51659 located_in GO:0005782"
xref: Reactome:R-HSA-9033102 "PR:P51659 located_in GO:0005829"
xref: UniProtKB:P51659
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
relationship: has_gene_template HGNC:5213 ! HSD17B4 (human)

[Term]
id: PR:Q9VXJ0
name: peroxisomal multifunctional enzyme type 2 (fruit fly)
def: "A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of fruit fly." [OMA:Q9VXJ0, PANTHER:PTHR24316:SF50, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mfe2" RELATED Gene-based [UniProtKB:Q9VXJ0]
synonym: "CG3415" RELATED Gene-based [UniProtKB:Q9VXJ0]
synonym: "DmMFE-2" EXACT [UniProtKB:Q9VXJ0]
synonym: "fly-HSD17B4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9VXJ0
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
relationship: has_gene_template FlyBase:FBgn0030731 ! Mfe2 (fruit fly)

[Term]
id: PR:P51659-2
name: peroxisomal multifunctional enzyme type 2 isoform h2 (human)
def: "A peroxisomal multifunctional enzyme type 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51659-2." [PRO:DNx, UniProtKB:P51659]
comment: Category=organism-sequence.
synonym: "hHSD17B4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51659-2
is_a: PR:P51659 ! peroxisomal multifunctional enzyme type 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51659-3
name: peroxisomal multifunctional enzyme type 2 isoform h3 (human)
def: "A peroxisomal multifunctional enzyme type 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51659-3." [PRO:DNx, UniProtKB:P51659]
comment: Category=organism-sequence.
synonym: "hHSD17B4/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51659-3
is_a: PR:P51659 ! peroxisomal multifunctional enzyme type 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51659-1
name: peroxisomal multifunctional enzyme type 2 isoform 1 (human)
def: "A peroxisomal multifunctional enzyme type 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51659-1." [PRO:DNx, UniProtKB:P51659]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hHSD17B4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51659-1
is_a: PR:P51659 ! peroxisomal multifunctional enzyme type 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51660-1
name: peroxisomal multifunctional enzyme type 2 isoform 1 (mouse)
def: "A peroxisomal multifunctional enzyme type 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHSD17B4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51660-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039671 ! peroxisomal multifunctional enzyme type 2 isoform 1

[Term]
id: PR:000008781
name: peroxisomal multifunctional enzyme type 2
def: "A protein that is a translation product of the human HSD17B4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DBP" RELATED []
synonym: "MFE-2" EXACT []
synonym: "MFP-2" EXACT []
synonym: "MPF-2" EXACT []
synonym: "SDR8C1" RELATED Gene-based []
synonym: "EDH17B4" RELATED Gene-based []
synonym: "HSD17B4" EXACT PRO-short-label [PRO:DNx]
synonym: "17-beta-HSD 4" EXACT []
synonym: "D-bifunctional protein" EXACT []
synonym: "multifunctional protein 2" EXACT []
synonym: "17-beta-hydroxysteroid dehydrogenase 4" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q02207
name: peroxisomal hydratase-dehydrogenase-epimerase (yeast)
def: "A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of yeast." [OMA:Q02207, PRO:DNx]
comment: Category=organism-gene.
synonym: "FOX2" RELATED Gene-based [UniProtKB:Q02207]
synonym: "YK108" RELATED Gene-based [UniProtKB:Q02207]
synonym: "YKR009C" RELATED Gene-based [UniProtKB:Q02207]
synonym: "yHSD17B4" EXACT PRO-short-label [PRO:DNx]
synonym: "HDE (yeast)" EXACT [UniProtKB:Q02207]
synonym: "MFP (yeast)" EXACT [UniProtKB:Q02207]
synonym: "multifunctional beta-oxidation protein (yeast)" EXACT [UniProtKB:Q02207]
xref: UniProtKB:Q02207
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
relationship: has_gene_template SGD:S000001717 ! FOX2 (yeast)

[Term]
id: PR:P97852-1
name: peroxisomal multifunctional enzyme type 2 isoform 1 (rat)
def: "A peroxisomal multifunctional enzyme type 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHSD17B4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97852-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039671 ! peroxisomal multifunctional enzyme type 2 isoform 1

[Term]
id: PR:000020197
name: peroxisomal multifunctional enzyme type 2, initiator methionine removed form
def: "A peroxisomal multifunctional enzyme type 2 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "HSD17B4/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008781 ! peroxisomal multifunctional enzyme type 2
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000039671
name: peroxisomal multifunctional enzyme type 2 isoform 1
def: "A peroxisomal multifunctional enzyme type 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51660-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HSD17B4/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008781 ! peroxisomal multifunctional enzyme type 2