[Term]
id: PR:P28845
name: 11-beta-hydroxysteroid dehydrogenase 1 (human)
def: "An 11-beta-hydroxysteroid dehydrogenase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P28845]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "HSD11" RELATED Gene-based [UniProtKB:P28845]
synonym: "HSD11L" RELATED Gene-based [UniProtKB:P28845]
synonym: "HSD11B1" RELATED Gene-based [UniProtKB:P28845]
synonym: "SDR26C1" RELATED Gene-based [UniProtKB:P28845]
synonym: "hHSD11B1" EXACT PRO-short-label [PRO:DNx]
synonym: "11-DH (human)" EXACT [UniProtKB:P28845]
synonym: "11-beta-HSD1 (human)" EXACT [UniProtKB:P28845]
synonym: "7-oxosteroid reductase (human)" EXACT [UniProtKB:P28845]
synonym: "corticosteroid 11-beta-dehydrogenase isozyme 1 (human)" EXACT [UniProtKB:P28845]
synonym: "short chain dehydrogenase/reductase family 26C member 1 (human)" EXACT [UniProtKB:P28845]
xref: UniProtKB:P28845
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008770 ! 11-beta-hydroxysteroid dehydrogenase 1
relationship: has_gene_template HGNC:5208 ! HSD11B1 (human)

[Term]
id: PR:P28845-1
name: 11-beta-hydroxysteroid dehydrogenase 1 isoform 1 (human)
def: "An 11-beta-hydroxysteroid dehydrogenase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHSD11B1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28845-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039207 ! 11-beta-hydroxysteroid dehydrogenase 1 isoform 1

[Term]
id: PR:000047898
name: 11-beta-hydroxysteroid dehydrogenase 1, initiator methionine removed form (human)
def: "An 11-beta-hydroxysteroid dehydrogenase 1 (human) that has had the initiator methionine removed. UniProtKB:P28845, 2-292." [PRO:DNx, Reactome:R-HSA-193975]
comment: Category=organism-modification.
synonym: "PRO_0000054619" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHSD11B1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28845, 2-292" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-193975 "PR:000047898 located_in GO:0005789"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P28845 ! 11-beta-hydroxysteroid dehydrogenase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000008770
name: 11-beta-hydroxysteroid dehydrogenase 1
def: "A protein that is a translation product of the human HSD11B1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "11-DH" EXACT []
synonym: "HSD11" RELATED Gene-based []
synonym: "HSD11L" RELATED Gene-based []
synonym: "HSD11B1" EXACT PRO-short-label [PRO:DNx]
synonym: "SDR26C1" RELATED Gene-based []
synonym: "11-beta-HSD1" EXACT []
synonym: "11beta-HSD1A" EXACT []
synonym: "7-oxosteroid reductase" EXACT []
synonym: "corticosteroid 11-beta-dehydrogenase isozyme 1" EXACT []
xref: IUPHARobj:2763
is_a: PR:000000001 ! protein