[Term]
id: PR:P00492
name: hypoxanthine-guanine phosphoribosyltransferase (human)
def: "A hypoxanthine-guanine phosphoribosyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00492]
comment: Category=organism-gene.
synonym: "HPRT" RELATED Gene-based [UniProtKB:P00492]
synonym: "HPRT1" RELATED Gene-based [UniProtKB:P00492]
synonym: "hHPRT1" EXACT PRO-short-label [PRO:DNx]
synonym: "HGPRT (human)" EXACT [UniProtKB:P00492]
synonym: "HGPRTase (human)" EXACT [UniProtKB:P00492]
xref: UniProtKB:P00492
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008735 ! hypoxanthine-guanine phosphoribosyltransferase
relationship: has_gene_template HGNC:5157 ! HPRT1 (human)

[Term]
id: PR:P00492-1
name: hypoxanthine-guanine phosphoribosyltransferase isoform 1 (human)
def: "A hypoxanthine-guanine phosphoribosyltransferase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHPRT1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P00492-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038606 ! hypoxanthine-guanine phosphoribosyltransferase isoform 1

[Term]
id: PR:000047893
name: hypoxanthine-guanine phosphoribosyltransferase, initiator methionine removed form (human)
def: "A hypoxanthine-guanine phosphoribosyltransferase (human) that has had the initiator methionine removed. UniProtKB:P00492, 2-218." [PRO:DNx, Reactome:R-HSA-56639]
comment: Category=organism-modification.
synonym: "PRO_0000139585" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHPRT1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00492, 2-218" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-56639 "PR:000047893 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P00492 ! hypoxanthine-guanine phosphoribosyltransferase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000008735
name: hypoxanthine-guanine phosphoribosyltransferase
def: "A protein that is a translation product of the human HPRT1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HPRT" RELATED Gene-based []
synonym: "HGPRT" EXACT []
synonym: "HPRT1" EXACT PRO-short-label [PRO:DNx]
synonym: "HPRT B" EXACT []
synonym: "HGPRTase" EXACT []
is_a: PR:000000001 ! protein