[Term] id: PR:P04035-1 name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform h1 (human) def: "A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04035-1." [PRO:DNx, UniProtKB:P04035] comment: Category=organism-sequence. synonym: "hHMGCR/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P04035-1 xref: Reactome:R-HSA-191308 "PR:P04035-1 located_in GO:0005789" is_a: PR:P04035 ! 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P04035-2 name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform h2 (human) def: "A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04035-2." [PRO:DNx, UniProtKB:P04035] comment: Category=organism-sequence. synonym: "hHMGCR/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P04035-2 xref: Reactome:R-HSA-191426 "PR:P04035-2 located_in GO:0005789" is_a: PR:P04035 ! 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P04035-3 name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform h3 (human) def: "A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04035-3." [PRO:DNx, UniProtKB:P04035] comment: Category=organism-sequence. synonym: "hHMGCR/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform HMGCR-1b (human)" EXACT [UniProtKB:P04035] xref: UniProtKB:P04035-3 is_a: PR:P04035 ! 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000008636 name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase def: "A protein that is a translation product of the human HMGCR gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HMGCR" EXACT PRO-short-label [PRO:DNx] synonym: "HMG-CoA reductase" EXACT [] xref: IUPHARobj:639 is_a: PR:000000001 ! protein [Term] id: PR:P04035 name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) def: "A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04035] comment: Category=organism-gene. synonym: "HMGCR" RELATED Gene-based [UniProtKB:P04035] synonym: "hHMGCR" EXACT PRO-short-label [PRO:DNx] synonym: "HMG-CoA reductase (human)" EXACT [UniProtKB:P04035] xref: Reactome:R-HSA-9621345 "PR:P04035 located_in GO:0005789" xref: UniProtKB:P04035 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008636 ! 3-hydroxy-3-methylglutaryl-coenzyme A reductase relationship: has_gene_template HGNC:5006 ! HMGCR (human)