[Term]
id: PR:Q9VNC3
name: holocarboxylase synthetase, isoform A (fruit fly)
def: "A biotin--protein ligase that is encoded in the genome of fruit fly." [PANTHER:PTHR12835:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "CG14670" RELATED Gene-based [UniProtKB:Q9VNC3]
synonym: "fly-HLCS" EXACT PRO-short-label [PRO:DNx]
synonym: "RE09732p (fruit fly)" EXACT [UniProtKB:Q9VNC3]
xref: UniProtKB:Q9VNC3
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000008617 ! biotin--protein ligase
relationship: has_gene_template FlyBase:FBgn0037332 ! Hcs (fruit fly)

[Term]
id: PR:Q54I33
name: uncharacterized protein, hlcs3 translation product (Dictyostelium discoideum)
def: "A biotin--protein ligase that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR12835:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-HLCS" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54I33
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008617 ! biotin--protein ligase
relationship: has_gene_template dictyBase:DDB_G0289035 ! hlcs3 (Dictyostelium discoideum)

[Term]
id: PR:P50747
name: biotin--protein ligase (human)
def: "A biotin--protein ligase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P50747]
comment: Category=organism-gene.
synonym: "HLCS" RELATED Gene-based [UniProtKB:P50747]
synonym: "hHLCS" EXACT PRO-short-label [PRO:DNx]
synonym: "biotin apo-protein ligase (human)" EXACT [UniProtKB:P50747]
xref: Reactome:R-HSA-2993867 "PR:P50747 located_in GO:0005829"
xref: UniProtKB:P50747
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008617 ! biotin--protein ligase
relationship: has_gene_template HGNC:4976 ! HLCS (human)

[Term]
id: PR:Q920N2
name: biotin--protein ligase (mouse)
def: "A biotin--protein ligase that is encoded in the genome of mouse." [OMA:Q920N2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hlcs" RELATED Gene-based [UniProtKB:Q920N2]
synonym: "mHLCS" EXACT PRO-short-label [PRO:DNx]
synonym: "biotin apo-protein ligase (mouse)" EXACT [UniProtKB:Q920N2]
xref: UniProtKB:Q920N2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008617 ! biotin--protein ligase
relationship: has_gene_template MGI:894646 ! Hlcs (mouse)

[Term]
id: PR:O14353
name: biotin--protein ligase (Schizosaccharomyces pombe 972h-)
def: "A biotin--protein ligase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR12835:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "bpl1" RELATED Gene-based [UniProtKB:O14353]
synonym: "SPBC30D10.07c" RELATED Gene-based [UniProtKB:O14353]
synonym: "Spom972h-HLCS" EXACT PRO-short-label [PRO:DNx]
synonym: "biotin apo-protein ligase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14353]
xref: UniProtKB:O14353
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000008617 ! biotin--protein ligase
relationship: has_gene_template PomBase:SPBC30D10.07c ! bpl1 (Schizosaccharomyces pombe)

[Term]
id: PR:000008617
name: biotin--protein ligase
def: "A protein that is a translation product of the human HLCS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HLCS" EXACT PRO-short-label [PRO:DNx]
synonym: "biotin apo-protein ligase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P50747-1
name: biotin--protein ligase isoform h1 (human)
def: "A biotin--protein ligase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P50747-1." [PRO:DNx, UniProtKB:P50747]
comment: Category=organism-sequence.
synonym: "hHLCS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P50747-1
is_a: PR:P50747 ! biotin--protein ligase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P50747-2
name: biotin--protein ligase isoform h2 (human)
def: "A biotin--protein ligase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P50747-2." [PRO:DNx, UniProtKB:P50747]
comment: Category=organism-sequence.
synonym: "hHLCS/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P50747-2
is_a: PR:P50747 ! biotin--protein ligase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens