[Term]
id: PR:000045223
name: histone H3.1t, initiator methionine removed acetylated 1 (human)
def: "A histone H3.1t (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-10, MOD:00064." [HIstome_var_Hs:Histone_H3.1t, PMID:12419248, PMID:16544193, PMID:17403718, PMID:17478518, PMID:17906200, PMID:18337721, PMID:19135889, PMID:20816089, PMID:20972224, PMID:21453398, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H3.1t:H3K9ac" BROAD [HIstome_ptm_Hs:H3K9ac]
synonym: "hHIST3H3/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16695, 2-136, Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q16695 ! histone H3.1t (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045224
name: histone H3.1t, initiator methionine removed acetylated 2 (human)
def: "A histone H3.1t (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-15 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-15, MOD:00064." [HIstome_var_Hs:Histone_H3.1t, PMID:12419248, PMID:16678094, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H3.1t:H3K14ac" BROAD [HIstome_ptm_Hs:H3K14ac]
synonym: "hHIST3H3/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16695, 2-136, Lys-15, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q16695 ! histone H3.1t (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q16695
name: histone H3.1t (human)
def: "A histone H3.1t that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16695]
comment: Category=organism-gene.
synonym: "H3-4" RELATED Gene-based [UniProtKB:Q16695]
synonym: "H3FT" RELATED Gene-based [UniProtKB:Q16695]
synonym: "hH3-4" EXACT PRO-short-label [PRO:DNx]
synonym: "HIST3H3" RELATED Gene-based [UniProtKB:Q16695]
synonym: "H3t (human)" EXACT [UniProtKB:Q16695]
synonym: "H3/g (human)" EXACT [UniProtKB:Q16695]
synonym: "H3/t (human)" EXACT [UniProtKB:Q16695]
synonym: "histone H3.4 (human)" EXACT [UniProtKB:Q16695]
xref: UniProtKB:Q16695
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008602 ! histone H3.1t
relationship: has_gene_template HGNC:4778 ! H3-4 (human)

[Term]
id: PR:000008602
name: histone H3.1t
def: "A histone H3 that is a translation product of the human H3-4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "H3t" EXACT []
synonym: "H3-4" EXACT PRO-short-label [PRO:DNx]
synonym: "H3/g" EXACT []
synonym: "H3/t" EXACT []
synonym: "H3FT" RELATED Gene-based []
synonym: "HIST3H3" RELATED Gene-based []
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000047874
name: histone H3.1t, initiator methionine removed dimethylated 1 (human)
def: "A histone H3.1t (human) that has had the initiator methionine removed and has been post-translationally modified to include dimethyl-L-lysine at position 5 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-5, MOD:00084." [PRO:DNx, Reactome:R-HSA-2245186]
comment: Category=organism-modification.
synonym: "hHIST3H3/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16695, 2-136, Lys-5, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2245186 "PR:000047874 located_in GO:0005654"
is_a: PR:Q16695 ! histone H3.1t (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000047873
name: histone H3.1t, initiator methionine removed form (human)
def: "A histone H3.1t (human) that has had the initiator methionine removed. UniProtKB:Q16695, 2-136." [PRO:DNx, Reactome:R-HSA-181914]
comment: Category=organism-modification.
synonym: "PRO_0000221248" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHIST3H3/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16695, 2-136" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-181914 "PR:000047873 located_in GO:0005654"
xref: TDR:6109
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q16695 ! histone H3.1t (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens