[Term]
id: PR:000044880
name: histone H1.5, initiator methionine removed phosphorylated 2 (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-138 of the amino acid sequence represented by UniProtKB:P16401. UniProtKB:P16401, 2-226, Thr-138, MOD:00047." [HIstome_var_Hs:Histone_H1.5, PMID:16377619, PMID:19007248, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.5:H1T137ph" BROAD [HIstome_ptm_Hs:H1T137ph]
synonym: "hHIST1H1B/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Thr-138, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16401 ! histone H1.5 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044881
name: histone H1.5, initiator methionine removed phosphorylated 3 (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-189 of the amino acid sequence represented by UniProtKB:P16401. UniProtKB:P16401, 2-226, Ser-189, MOD:00046." [HIstome_var_Hs:Histone_H1.5, PMID:16377619, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.5:H1S188ph" BROAD [HIstome_ptm_Hs:H1S188ph]
synonym: "hHIST1H1B/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Ser-189, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16401 ! histone H1.5 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044882
name: histone H1.5, initiator methionine removed phosphorylated 4 (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-18 of the amino acid sequence represented by UniProtKB:P16401. UniProtKB:P16401, 2-226, Ser-18, MOD:00046." [HIstome_var_Hs:Histone_H1.5, PMID:16083285, PMID:16377619, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.5:H1S17ph" BROAD [HIstome_ptm_Hs:H1S17ph]
synonym: "hHIST1H1B/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Ser-18, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16401 ! histone H1.5 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044883
name: histone H1.5, initiator methionine removed phosphorylated 5 (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-173 of the amino acid sequence represented by UniProtKB:P16401. UniProtKB:P16401, 2-226, Ser-173, MOD:00046." [HIstome_var_Hs:Histone_H1.5, PMID:16377619, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.5:H1S172ph" BROAD [HIstome_ptm_Hs:H1S172ph]
synonym: "hHIST1H1B/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Ser-173, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16401 ! histone H1.5 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044884
name: histone H1.5, initiator methionine removed phosphorylated 6 (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-11 of the amino acid sequence represented by UniProtKB:P16401. UniProtKB:P16401, 2-226, Thr-11, MOD:00047." [HIstome_var_Hs:Histone_H1.5, PMID:16377619, PMID:19136008, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.5:H1T10ph" BROAD [HIstome_ptm_Hs:H1T10ph]
synonym: "hHIST1H1B/InitMet-/Phos:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Thr-11, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16401 ! histone H1.5 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044885
name: histone H1.5, initiator methionine removed phosphorylated 7 (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-155 of the amino acid sequence represented by UniProtKB:P16401. UniProtKB:P16401, 2-226, Thr-155, MOD:00047." [HIstome_var_Hs:Histone_H1.5, PMID:16377619, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.5:H1T154ph" BROAD [HIstome_ptm_Hs:H1T154ph]
synonym: "hHIST1H1B/InitMet-/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Thr-155, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16401 ! histone H1.5 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P16401
name: histone H1.5 (human)
def: "A histone H1.5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16401]
comment: Category=organism-gene.
synonym: "H1-5" RELATED Gene-based [UniProtKB:P16401]
synonym: "H1F5" RELATED Gene-based [UniProtKB:P16401]
synonym: "hH1-5" EXACT PRO-short-label [PRO:DNx]
synonym: "HIST1H1B" RELATED Gene-based [UniProtKB:P16401]
synonym: "histone H1a (human)" BROAD [UniProtKB:P16401]
synonym: "histone H1b (human)" BROAD [UniProtKB:P16401]
synonym: "histone H1s-3 (human)" EXACT [UniProtKB:P16401]
xref: UniProtKB:P16401
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008575 ! histone H1.5
relationship: has_gene_template HGNC:4719 ! H1-5 (human)

[Term]
id: PR:000029022
name: histone H1.5, initiator methionine removed phosphorylated 1 (human)
def: "A histone H1.5, initiator methionine removed phosphorylated 1 in human. Phosphorylated in 5 sites, last site is Thr-11 which is phosphorylated by GSK3-beta. UniProtKB:P16401, 2-226, Thr-11, MOD:00047|MOD:00696." [PMID:19136008, PRO:CNA]
comment: Category=organism-modification. Kinase=("GSK3B"; PR:P49841; Thr-11).
synonym: "hHIST1H1B/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000195909, Thr-11, MOD:00047|MOD:00696" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226, Thr-11, MOD:00047|MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029021 ! histone H1.5, initiator methionine removed phosphorylated 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000047699
name: histone H1.5, initiator methionine removed form (human)
def: "A histone H1.5 (human) that has had the initiator methionine removed. UniProtKB:P16401, 2-226." [PRO:DNx, Reactome:R-HSA-211248]
comment: Category=organism-modification.
synonym: "PRO_0000195909" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHIST1H1B/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16401, 2-226" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-211248 "PR:000047699 located_in GO:0005654"
xref: TDR:13054
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P16401 ! histone H1.5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16401-1
name: histone H1.5 isoform 1 (human)
def: "A histone H1.5 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hHIST1H1B/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16401-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029019 ! histone H1.5 isoform 1

[Term]
id: PR:000008575
name: histone H1.5
def: "A histone H1 that is a translation product of the human H1-5 gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "H1b" EXACT []
synonym: "H1-5" EXACT PRO-short-label [PRO:DNx]
synonym: "H1F5" RELATED Gene-based []
synonym: "H1 VAR.5" EXACT []
synonym: "HIST1H1B" RELATED Gene-based []
synonym: "histone H1a" BROAD []
is_a: PR:000038372 ! histone H1