[Term]
id: PR:O15379
name: histone deacetylase 3 (human)
def: "A histone deacetylase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15379]
comment: Category=organism-gene.
synonym: "HDAC3" RELATED Gene-based [UniProtKB:O15379]
synonym: "hHDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "HD3 (human)" EXACT [UniProtKB:O15379]
synonym: "RPD3-2 (human)" EXACT [UniProtKB:O15379]
synonym: "SMAP45 (human)" EXACT [UniProtKB:O15379]
synonym: "protein deacylase HDAC3 (human)" EXACT [UniProtKB:O15379]
synonym: "protein deacetylase HDAC3 (human)" EXACT [UniProtKB:O15379]
xref: Reactome:R-HSA-442464 "PR:O15379 located_in GO:0005654"
xref: Reactome:R-HSA-6813777 "PR:O15379 located_in GO:0005829"
xref: UniProtKB:O15379
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template HGNC:4854 ! HDAC3 (human)

[Term]
id: PR:O15379-1
name: histone deacetylase 3 isoform 1 (human)
def: "A histone deacetylase 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHDAC3/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "histone deacetylase 3 isoform RPD3-2B (human)" EXACT [UniProtKB:O15379]
xref: UniProtKB:O15379-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038069 ! histone deacetylase 3 isoform 1

[Term]
id: PR:000008482
name: histone deacetylase 3
def: "A protein that is a translation product of the human HDAC3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HD3" EXACT []
synonym: "HDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "RPD3-2" EXACT []
synonym: "SMAP45" EXACT []
synonym: "protein deacylase HDAC3" EXACT []
synonym: "protein deacetylase HDAC3" EXACT []
xref: IUPHARobj:2617
is_a: PR:000000001 ! protein

[Term]
id: PR:000049894
name: histone deacetylase 3 isoform 1 unphosphorylated 1 (human)
def: "A histone deacetylase 3 isoform 1 unphosphorylated 1 in human. UniProtKB:O15379-1, Ser-424, PR:000026291." [PMID:27798112, PRO:LN]
comment: Category=organism-modification.
synonym: "hHDAC3/iso:1/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15379-1, Ser-424, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000049892 ! histone deacetylase 3 isoform 1 unphosphorylated 1

[Term]
id: PR:000049891
name: histone deacetylase 3 isoform 1 phosphorylated 1 (human)
def: "A histone deacetylase 3 isoform 1 phosphorylated 1 in human. UniProtKB:O15379-1, Ser-424, MOD:00046." [PMID:27798112, PRO:LN]
comment: Category=organism-modification.
synonym: "hHDAC3/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15379-1, Ser-424, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000049889 ! histone deacetylase 3 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:O15379-2
name: histone deacetylase 3 isoform h2 (human)
def: "A histone deacetylase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15379-2." [PRO:DNx, UniProtKB:O15379]
comment: Category=organism-sequence.
synonym: "hHDAC3/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "histone deacetylase 3 isoform RPD3-2A (human)" EXACT [UniProtKB:O15379]
xref: UniProtKB:O15379-2
is_a: PR:O15379 ! histone deacetylase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens