[Term]
id: PR:O88895
name: histone deacetylase 3 (mouse)
def: "A histone deacetylase 3 that is encoded in the genome of mouse." [OMA:O88895, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hdac3" RELATED Gene-based [UniProtKB:O88895]
synonym: "mHDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "HD3 (mouse)" EXACT [UniProtKB:O88895]
synonym: "protein deacylase HDAC3 (mouse)" EXACT [UniProtKB:O88895]
synonym: "protein deacetylase HDAC3 (mouse)" EXACT [UniProtKB:O88895]
xref: UniProtKB:O88895
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template MGI:1343091 ! Hdac3 (mouse)

[Term]
id: PR:O15379
name: histone deacetylase 3 (human)
def: "A histone deacetylase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15379]
comment: Category=organism-gene.
synonym: "HDAC3" RELATED Gene-based [UniProtKB:O15379]
synonym: "hHDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "HD3 (human)" EXACT [UniProtKB:O15379]
synonym: "RPD3-2 (human)" EXACT [UniProtKB:O15379]
synonym: "SMAP45 (human)" EXACT [UniProtKB:O15379]
synonym: "protein deacylase HDAC3 (human)" EXACT [UniProtKB:O15379]
synonym: "protein deacetylase HDAC3 (human)" EXACT [UniProtKB:O15379]
xref: Reactome:R-HSA-442464 "PR:O15379 located_in GO:0005654"
xref: Reactome:R-HSA-6813777 "PR:O15379 located_in GO:0005829"
xref: UniProtKB:O15379
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template HGNC:4854 ! HDAC3 (human)

[Term]
id: PR:P53096
name: probable histone deacetylase HOS2 (yeast)
def: "A histone deacetylase 3 that is encoded in the genome of yeast." [OMA:P53096, PRO:DNx]
comment: Category=organism-gene.
synonym: "HOS2" RELATED Gene-based [UniProtKB:P53096]
synonym: "G1330" RELATED Gene-based [UniProtKB:P53096]
synonym: "yHDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "YGL194C" RELATED Gene-based [UniProtKB:P53096]
xref: UniProtKB:P53096
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template SGD:S000003162 ! HOS2 (yeast)

[Term]
id: PR:000049889
name: histone deacetylase 3 isoform 1 phosphorylated 1
def: "A histone deacetylase 3 isoform 1 that has been phosphorylated at the position equivalent to Ser-424 of the amino acid sequence represented by UniProtKB:O88895-1. Example: UniProtKB:O88895-1, Ser-424, MOD:00046." [PMID:27798112, PRO:LN]
comment: Category=modification.
synonym: "HDAC3/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000038069 ! histone deacetylase 3 isoform 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000008482
name: histone deacetylase 3
def: "A protein that is a translation product of the human HDAC3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HD3" EXACT []
synonym: "HDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "RPD3-2" EXACT []
synonym: "SMAP45" EXACT []
synonym: "protein deacylase HDAC3" EXACT []
synonym: "protein deacetylase HDAC3" EXACT []
xref: IUPHARobj:2617
is_a: PR:000000001 ! protein

[Term]
id: PR:000038069
name: histone deacetylase 3 isoform 1
def: "A histone deacetylase 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15379-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HDAC3/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008482 ! histone deacetylase 3

[Term]
id: PR:000049891
name: histone deacetylase 3 isoform 1 phosphorylated 1 (human)
def: "A histone deacetylase 3 isoform 1 phosphorylated 1 in human. UniProtKB:O15379-1, Ser-424, MOD:00046." [PMID:27798112, PRO:LN]
comment: Category=organism-modification.
synonym: "hHDAC3/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15379-1, Ser-424, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000049889 ! histone deacetylase 3 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000049892
name: histone deacetylase 3 isoform 1 unphosphorylated 1
def: "A histone deacetylase 3 isoform 1 that lacks phosphorylation at the position equivalent to Ser-424 of the amino acid sequence represented by UniProtKB:O88895-1. Example: UniProtKB:O88895-1, Ser-424, PR:000026291." [PMID:27798112, PRO:LN]
comment: Category=modification.
synonym: "HDAC3/iso:1/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000038069 ! histone deacetylase 3 isoform 1

[Term]
id: PR:Q6P6W3-1
name: histone deacetylase 3 isoform 1 (rat)
def: "A histone deacetylase 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHDAC3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6P6W3-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038069 ! histone deacetylase 3 isoform 1

[Term]
id: PR:P56520
name: histone deacetylase 3 (chicken)
def: "A histone deacetylase 3 that is encoded in the genome of chicken." [OMA:P56520, PANTHER:PTHR10625:SF59, PRO:DNx]
comment: Category=organism-gene.
synonym: "HDAC3" RELATED Gene-based [UniProtKB:P56520]
synonym: "chick-HDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "HD3 (chicken)" EXACT [UniProtKB:P56520]
synonym: "protein deacylase HDAC3 (chicken)" EXACT [UniProtKB:P56520]
synonym: "protein deacetylase HDAC3 (chicken)" EXACT [UniProtKB:P56520]
xref: UniProtKB:P56520
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template NCBIGene:395506 ! HDAC3 (chicken)

[Term]
id: PR:Q803C3
name: histone deacetylase 3 (zebrafish)
def: "A histone deacetylase 3 that is encoded in the genome of zebrafish." [PANTHER:PTHR10625:SF59, PRO:DNx]
comment: Category=organism-gene.
synonym: "hdac3" RELATED Gene-based [UniProtKB:Q803C3]
synonym: "z-HDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:55927" RELATED Gene-based [UniProtKB:Q803C3]
synonym: "HD3 (zebrafish)" EXACT [UniProtKB:Q803C3]
synonym: "protein deacylase HDAC3 (zebrafish)" EXACT [UniProtKB:Q803C3]
synonym: "protein deacetylase HDAC3 (zebrafish)" EXACT [UniProtKB:Q803C3]
xref: UniProtKB:Q803C3
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template ZFIN:ZDB-GENE-040426-847 ! hdac3 (zebrafish)

[Term]
id: PR:000049894
name: histone deacetylase 3 isoform 1 unphosphorylated 1 (human)
def: "A histone deacetylase 3 isoform 1 unphosphorylated 1 in human. UniProtKB:O15379-1, Ser-424, PR:000026291." [PMID:27798112, PRO:LN]
comment: Category=organism-modification.
synonym: "hHDAC3/iso:1/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15379-1, Ser-424, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000049892 ! histone deacetylase 3 isoform 1 unphosphorylated 1

[Term]
id: PR:000049890
name: histone deacetylase 3 isoform Long phosphorylated 1 (mouse)
def: "A histone deacetylase 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:O88895-1, Ser-424, MOD:00046." [PMID:27798112, PRO:LN]
comment: Category=organism-modification.
synonym: "mHDAC3/iso:Long/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O88895-1, Ser-424, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000049889 ! histone deacetylase 3 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:O88895-2
name: histone deacetylase 3 isoform Short (mouse)
def: "A histone deacetylase 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88895-2." [PRO:DNx, UniProtKB:O88895]
comment: Category=organism-sequence.
synonym: "mHDAC3/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88895-2
is_a: PR:O88895 ! histone deacetylase 3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O88895-1
name: histone deacetylase 3 isoform Long (mouse)
def: "A histone deacetylase 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:O88895]
comment: Category=organism-sequence.
synonym: "mHDAC3/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88895-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038069 ! histone deacetylase 3 isoform 1

[Term]
id: PR:000049893
name: histone deacetylase 3 isoform Long unphosphorylated 1 (mouse)
def: "A histone deacetylase 3 isoform 1 unphosphorylated 1 in mouse. UniProtKB:O88895-1, Ser-424, PR:000026291." [PMID:27798112, PRO:LN]
comment: Category=organism-modification.
synonym: "mHDAC3/iso:Long/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O88895-1, Ser-424, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000049892 ! histone deacetylase 3 isoform 1 unphosphorylated 1

[Term]
id: PR:Q8H0W2
name: histone deacetylase 9 (Arabidopsis thaliana)
def: "A histone deacetylase 3 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q8H0W2, PRO:DNx]
comment: Category=organism-gene.
synonym: "HDA9" RELATED Gene-based [UniProtKB:Q8H0W2]
synonym: "HDAC9" RELATED Gene-based [UniProtKB:Q8H0W2]
synonym: "AtHDAC9" EXACT [UniProtKB:Q8H0W2]
synonym: "At-HDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "At3g44680" RELATED Gene-based [UniProtKB:Q8H0W2]
synonym: "T18B22.80" RELATED Gene-based [UniProtKB:Q8H0W2]
xref: UniProtKB:Q8H0W2
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template Araport:AT3G44680 ! HDA9 (Arabidopsis thaliana)

[Term]
id: PR:Q55BW2
name: histone deacetylase B (Dictyostelium discoideum)
def: "A histone deacetylase 3 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55BW2, PRO:DNx]
comment: Category=organism-gene.
synonym: "hdaB" RELATED Gene-based [UniProtKB:Q55BW2]
synonym: "DdHdaB" EXACT [UniProtKB:Q55BW2]
synonym: "Dicty-HDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0270338" RELATED Gene-based [UniProtKB:Q55BW2]
synonym: "type-1 histone deacetylase 2 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55BW2]
xref: UniProtKB:Q55BW2
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template dictyBase:DDB_G0270338 ! hdaB (Dictyostelium discoideum)

[Term]
id: PR:O13298
name: histone deacetylase phd1 (Schizosaccharomyces pombe 972h-)
def: "A histone deacetylase 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O13298, PRO:DNx]
comment: Category=organism-gene.
synonym: "hda1" RELATED Gene-based [UniProtKB:O13298]
synonym: "phd1" RELATED Gene-based [UniProtKB:O13298]
synonym: "SPAC3G9.07c" RELATED Gene-based [UniProtKB:O13298]
synonym: "Spom972h-HDAC3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O13298
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template PomBase:SPAC3G9.07c ! phd1 (Schizosaccharomyces pombe)

[Term]
id: PR:Q6P6W3
name: histone deacetylase 3 (rat)
def: "A histone deacetylase 3 that is encoded in the genome of rat." [OMA:Q6P6W3, PANTHER:PTHR10625:SF59, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hdac3" RELATED Gene-based [UniProtKB:Q6P6W3]
synonym: "rHDAC3" EXACT PRO-short-label [PRO:DNx]
synonym: "HD3 (rat)" EXACT [UniProtKB:Q6P6W3]
synonym: "protein deacylase HDAC3 (rat)" EXACT [UniProtKB:Q6P6W3]
synonym: "protein deacetylase HDAC3 (rat)" EXACT [UniProtKB:Q6P6W3]
xref: UniProtKB:Q6P6W3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008482 ! histone deacetylase 3
relationship: has_gene_template RGD:619977 ! Hdac3 (rat)

[Term]
id: PR:O15379-1
name: histone deacetylase 3 isoform 1 (human)
def: "A histone deacetylase 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHDAC3/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "histone deacetylase 3 isoform RPD3-2B (human)" EXACT [UniProtKB:O15379]
xref: UniProtKB:O15379-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038069 ! histone deacetylase 3 isoform 1

[Term]
id: PR:O15379-2
name: histone deacetylase 3 isoform h2 (human)
def: "A histone deacetylase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15379-2." [PRO:DNx, UniProtKB:O15379]
comment: Category=organism-sequence.
synonym: "hHDAC3/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "histone deacetylase 3 isoform RPD3-2A (human)" EXACT [UniProtKB:O15379]
xref: UniProtKB:O15379-2
is_a: PR:O15379 ! histone deacetylase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens