[Term]
id: PR:P61295
name: heart- and neural crest derivatives-expressed protein 2 (rat)
def: "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of rat." [OMA:P61295, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dhand" RELATED Gene-based [UniProtKB:P61295]
synonym: "Hand2" RELATED Gene-based [UniProtKB:P61295]
synonym: "rHAND2" EXACT PRO-short-label [PRO:DNx]
synonym: "dHAND (rat)" EXACT [UniProtKB:P61295]
synonym: "deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 (rat)" EXACT [UniProtKB:P61295]
xref: UniProtKB:P61295
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008440 ! heart- and neural crest derivatives-expressed protein 2
relationship: has_gene_template RGD:621207 ! Hand2 (rat)

[Term]
id: PR:P61296-2
name: heart- and neural crest derivatives-expressed protein 2 isoform h2 (human)
def: "A heart- and neural crest derivatives-expressed protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61296-2." [PRO:DNx, UniProtKB:P61296]
comment: Category=organism-sequence.
synonym: "hHAND2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61296-2
is_a: PR:P61296 ! heart- and neural crest derivatives-expressed protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P61296
name: heart- and neural crest derivatives-expressed protein 2 (human)
def: "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P61296]
comment: Category=organism-gene.
synonym: "DHAND" RELATED Gene-based [UniProtKB:P61296]
synonym: "HAND2" RELATED Gene-based [UniProtKB:P61296]
synonym: "hHAND2" EXACT PRO-short-label [PRO:DNx]
synonym: "BHLHA26" RELATED Gene-based [UniProtKB:P61296]
synonym: "class A basic helix-loop-helix protein 26 (human)" EXACT [UniProtKB:P61296]
synonym: "deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 (human)" EXACT [UniProtKB:P61296]
xref: UniProtKB:P61296
xref: Reactome:R-HSA-9007820 "PR:P61296 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008440 ! heart- and neural crest derivatives-expressed protein 2
relationship: has_gene_template HGNC:4808 ! HAND2 (human)

[Term]
id: PR:P57102
name: heart- and neural crest derivatives-expressed protein 2 (zebrafish)
def: "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of zebrafish." [OMA:P57102, PRO:DNx]
comment: Category=organism-gene.
synonym: "dhand" RELATED Gene-based [UniProtKB:P57102]
synonym: "hand2" RELATED Gene-based [UniProtKB:P57102]
synonym: "z-HAND2" EXACT PRO-short-label [PRO:DNx]
synonym: "dHAND (zebrafish)" EXACT [UniProtKB:P57102]
synonym: "deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 (zebrafish)" EXACT [UniProtKB:P57102]
xref: UniProtKB:P57102
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000008440 ! heart- and neural crest derivatives-expressed protein 2
relationship: has_gene_template ZFIN:ZDB-GENE-000511-1 ! hand2 (zebrafish)

[Term]
id: PR:Q61039
name: heart- and neural crest derivatives-expressed protein 2 (mouse)
def: "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of mouse." [OMA:Q61039, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hed" RELATED Gene-based [UniProtKB:Q61039]
synonym: "Dhand" RELATED Gene-based [UniProtKB:Q61039]
synonym: "Hand2" RELATED Gene-based [UniProtKB:Q61039]
synonym: "Thing2" RELATED Gene-based [UniProtKB:Q61039]
synonym: "mHAND2" EXACT PRO-short-label [PRO:DNx]
synonym: "dHAND (mouse)" EXACT [UniProtKB:Q61039]
synonym: "thing-2 (mouse)" EXACT [UniProtKB:Q61039]
synonym: "helix-loop-helix transcription factor expressed in embryo and deciduum (mouse)" EXACT [UniProtKB:Q61039]
synonym: "deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 (mouse)" EXACT [UniProtKB:Q61039]
xref: UniProtKB:Q61039
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008440 ! heart- and neural crest derivatives-expressed protein 2
relationship: has_gene_template MGI:103580 ! Hand2 (mouse)

[Term]
id: PR:P61295-1
name: heart- and neural crest derivatives-expressed protein 2 isoform 1 (rat)
def: "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHAND2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61295-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039937 ! heart- and neural crest derivatives-expressed protein 2 isoform 1

[Term]
id: PR:Q90690
name: heart- and neural crest derivatives-expressed protein 2 (chicken)
def: "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of chicken." [OMA:Q90690, PRO:DNx]
comment: Category=organism-gene.
synonym: "DHAND" RELATED Gene-based [UniProtKB:Q90690]
synonym: "HAND2" RELATED Gene-based [UniProtKB:Q90690]
synonym: "chick-HAND2" EXACT PRO-short-label [PRO:DNx]
synonym: "dHAND (chicken)" EXACT [UniProtKB:Q90690]
synonym: "deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 (chicken)" EXACT [UniProtKB:Q90690]
xref: UniProtKB:Q90690
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000008440 ! heart- and neural crest derivatives-expressed protein 2
relationship: has_gene_template CGNC:66214 ! HAND2 (chicken)

[Term]
id: PR:P61296-1
name: heart- and neural crest derivatives-expressed protein 2 isoform 1 (human)
def: "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHAND2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61296-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039937 ! heart- and neural crest derivatives-expressed protein 2 isoform 1

[Term]
id: PR:000039937
name: heart- and neural crest derivatives-expressed protein 2 isoform 1
def: "A heart- and neural crest derivatives-expressed protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61296-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HAND2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008440 ! heart- and neural crest derivatives-expressed protein 2

[Term]
id: PR:000008440
name: heart- and neural crest derivatives-expressed protein 2
def: "A basic helix-loop-helix transcription factor HAND that is a translation product of the human HAND2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Hed" RELATED Gene-based []
synonym: "DHAND" RELATED Gene-based []
synonym: "HAND2" EXACT PRO-short-label [PRO:DNx]
synonym: "dHAND" EXACT []
synonym: "Thing2" RELATED Gene-based []
synonym: "BHLHA26" RELATED Gene-based []
synonym: "bHLHa26" EXACT []
synonym: "thing-2" EXACT []
synonym: "class A basic helix-loop-helix protein 26" EXACT []
synonym: "helix-loop-helix transcription factor expressed in embryo and deciduum" EXACT []
synonym: "deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2" EXACT []
is_a: PR:000027804 ! basic helix-loop-helix transcription factor HAND

[Term]
id: PR:Q61039-1
name: heart- and neural crest derivatives-expressed protein 2 isoform 1 (mouse)
def: "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHAND2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q61039-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039937 ! heart- and neural crest derivatives-expressed protein 2 isoform 1