[Term]
id: PR:P0C0S5
name: histone H2A.Z (human)
def: "A histone H2A.Z that is encoded in the genome of human." [PRO:DNx, UniProtKB:P0C0S5]
comment: Category=organism-gene.
synonym: "H2AZ" RELATED Gene-based [UniProtKB:P0C0S5]
synonym: "H2AFZ" RELATED Gene-based [UniProtKB:P0C0S5]
synonym: "H2AZ1" RELATED Gene-based [UniProtKB:P0C0S5]
synonym: "hH2AZ1" EXACT PRO-short-label [PRO:DNx]
synonym: "H2A/z (human)" EXACT [UniProtKB:P0C0S5]
xref: UniProtKB:P0C0S5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008421 ! histone H2A.Z
relationship: has_gene_template HGNC:4741 ! H2AZ1 (human)

[Term]
id: PR:P0C0S5-1
name: histone H2A.Z isoform 1 (human)
def: "A histone H2A.Z isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hH2AFZ/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P0C0S5-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038795 ! histone H2A.Z isoform 1

[Term]
id: PR:000045023
name: histone H2A.Z, initiator methionine removed ubiquitinated 1 (human)
def: "A histone H2A.Z (human) that has had the initiator methionine removed and that has been ubiquitinated at the position equivalent to Lys-122 of the amino acid sequence represented by UniProtKB:P0C0S5. UniProtKB:P0C0S5, 2-128, Lys-122, MOD:01148." [HIstome_var_Hs:Histone_H2A.Z, PMID:17636032, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2A.Z:H2AK121ub" BROAD [HIstome_ptm_Hs:H2AK121ub]
synonym: "hH2AFZ/InitMet-/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P0C0S5, 2-128, Lys-122, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P0C0S5 ! histone H2A.Z (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000008421
name: histone H2A.Z
def: "A histone H2A that is a translation product of the human H2AZ1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "H2AZ" RELATED Gene-based []
synonym: "H2A/z" EXACT []
synonym: "H2AFZ" RELATED Gene-based []
synonym: "H2AZ1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027547 ! histone H2A

[Term]
id: PR:000047671
name: histone H2A.Z, initiator methionine removed form (human)
def: "A histone H2A.Z (human) that has had the initiator methionine removed. UniProtKB:P0C0S5, 2-128." [PRO:DNx, Reactome:R-HSA-181897, Reactome:R-HSA-977575]
comment: Category=organism-modification.
synonym: "PRO_0000055297" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hH2AFZ/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P0C0S5, 2-128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-181897 "PR:000047671 located_in GO:0005654"
xref: Reactome:R-HSA-977575 "PR:000047671 located_in GO:0005576"
xref: TDR:1144
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P0C0S5 ! histone H2A.Z (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens