[Term]
id: PR:000047659
name: guanylate kinase, initiator methionine removed form (human)
def: "A guanylate kinase (human) that has had the initiator methionine removed. UniProtKB:Q16774, 2-197." [PRO:DNx, Reactome:R-HSA-58048]
comment: Category=organism-modification.
synonym: "PRO_0000170651" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGUK1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16774, 2-197" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-58048 "PR:000047659 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q16774 ! guanylate kinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000008356
name: guanylate kinase
def: "A protein that is a translation product of the human GUK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GMK" RELATED Gene-based []
synonym: "GMPK" RELATED Gene-based []
synonym: "GUK1" EXACT PRO-short-label [PRO:DNx]
synonym: "GMP kinase" EXACT []
synonym: "guanylate kinase 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q16774
name: guanylate kinase (human)
def: "A guanylate kinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16774]
comment: Category=organism-gene.
synonym: "GMK" RELATED Gene-based [UniProtKB:Q16774]
synonym: "GMPK" RELATED Gene-based [UniProtKB:Q16774]
synonym: "GUK1" RELATED Gene-based [UniProtKB:Q16774]
synonym: "hGUK1" EXACT PRO-short-label [PRO:DNx]
synonym: "GMP kinase (human)" EXACT [UniProtKB:Q16774]
synonym: "guanylate kinase 1 (human)" EXACT [UniProtKB:Q16774]
xref: DTO:03100226
xref: UniProtKB:Q16774
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008356 ! guanylate kinase
relationship: has_gene_template HGNC:4693 ! GUK1 (human)

[Term]
id: PR:Q16774-2
name: guanylate kinase isoform h2 (human)
def: "A guanylate kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16774-2." [PRO:DNx, UniProtKB:Q16774]
comment: Category=organism-sequence.
synonym: "hGUK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16774-2
is_a: PR:Q16774 ! guanylate kinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16774-3
name: guanylate kinase isoform h3 (human)
def: "A guanylate kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16774-3." [PRO:DNx, UniProtKB:Q16774]
comment: Category=organism-sequence.
synonym: "hGUK1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16774-3
is_a: PR:Q16774 ! guanylate kinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16774-1
name: guanylate kinase isoform h1 (human)
def: "A guanylate kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16774-1." [PRO:DNx, UniProtKB:Q16774]
comment: Category=organism-sequence.
synonym: "hGUK1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16774-1
is_a: PR:Q16774 ! guanylate kinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens