[Term]
id: PR:P49840
name: glycogen synthase kinase-3 alpha (human)
def: "A glycogen synthase kinase-3 alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49840]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "GSK3A" RELATED Gene-based [UniProtKB:P49840]
synonym: "hGSK3A" EXACT PRO-short-label [PRO:DNx]
synonym: "GSK-3 alpha (human)" EXACT [UniProtKB:P49840]
synonym: "serine/threonine-protein kinase GSK3A (human)" EXACT [UniProtKB:P49840]
xref: DTO:03100164
xref: UniProtKB:P49840
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008287 ! glycogen synthase kinase-3 alpha
relationship: has_gene_template HGNC:4616 ! GSK3A (human)

[Term]
id: PR:000045808
name: glycogen synthase kinase-3 alpha phosphorylated 1 (human)
def: "A glycogen synthase kinase-3 alpha (human) that has been phosphorylated at Ser-21. UniProtKB:P49840, Ser-21, MOD:00046." [PMID:11035810, iPTMnet:P49840]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11035810). Status=unreviewed.
synonym: "hGSK3A/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49840, Ser-21, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-198352 "PR:000045808 located_in GO:0005829"
is_a: PR:P49840 ! glycogen synthase kinase-3 alpha (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000008287
name: glycogen synthase kinase-3 alpha
def: "A glycogen synthase kinase 3 that is a translation product of the human GSK3A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GSK3A" EXACT PRO-short-label [PRO:DNx]
synonym: "GSK-3 alpha" EXACT []
synonym: "serine/threonine-protein kinase GSK3A" EXACT []
xref: IUPHARobj:2029
is_a: PR:000050019 ! glycogen synthase kinase 3

[Term]
id: PR:000047634
name: glycogen synthase kinase-3 alpha, initiator methionine removed form (human)
def: "A glycogen synthase kinase-3 alpha (human) that has had the initiator methionine removed. UniProtKB:P49840, 2-483." [PRO:DNx, Reactome:R-HSA-198326]
comment: Category=organism-modification.
synonym: "PRO_0000085978" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGSK3A/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49840, 2-483" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-198326 "PR:000047634 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P49840 ! glycogen synthase kinase-3 alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens