[Term]
id: PR:P36970
name: phospholipid hydroperoxide glutathione peroxidase (rat)
def: "A phospholipid hydroperoxide glutathione peroxidase that is encoded in the genome of rat." [OMA:P36970, PRO:DAN]
comment: Category=organism-gene.
synonym: "Gpx4" RELATED Gene-based [UniProtKB:P36970]
synonym: "rGPX4" EXACT PRO-short-label [PRO:DNx]
synonym: "GPx-4 (rat)" EXACT [UniProtKB:P36970]
synonym: "PHGPx (rat)" EXACT [UniProtKB:P36970]
synonym: "GSHPx-4 (rat)" EXACT [UniProtKB:P36970]
synonym: "glutathione peroxidase 4 (rat)" EXACT [UniProtKB:P36970]
xref: UniProtKB:P36970
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008213 ! phospholipid hydroperoxide glutathione peroxidase
relationship: has_gene_template RGD:69226 ! Gpx4 (rat)

[Term]
id: PR:P36970-3
name: phospholipid hydroperoxide glutathione peroxidase isoform Nuclear (rat)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Nuclear that is encoded in the genome of rat." [PRO:DAN, UniProtKB:P36970]
comment: Category=organism-sequence.
synonym: "rGPX4/iso:Nuclear" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36970-3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000034128 ! phospholipid hydroperoxide glutathione peroxidase isoform Nuclear

[Term]
id: PR:P36970-2
name: phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic (rat)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic that is encoded in the genome of rat." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "rGPX4/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36970-2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000035963 ! phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic

[Term]
id: PR:000035963
name: phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic
def: "A phospholipid hydroperoxide glutathione peroxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36969-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GPX4/iso:cytoplasmic" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008213 ! phospholipid hydroperoxide glutathione peroxidase

[Term]
id: PR:000035962
name: phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial
def: "A phospholipid hydroperoxide glutathione peroxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36969-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GPX4/iso:mitochondrial" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008213 ! phospholipid hydroperoxide glutathione peroxidase

[Term]
id: PR:P36969
name: phospholipid hydroperoxide glutathione peroxidase (human)
def: "A phospholipid hydroperoxide glutathione peroxidase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P36969]
comment: Category=organism-gene.
synonym: "GPX4" RELATED Gene-based [UniProtKB:P36969]
synonym: "hGPX4" EXACT PRO-short-label [PRO:DNx]
synonym: "GPx-4 (human)" EXACT [UniProtKB:P36969]
synonym: "PHGPx (human)" EXACT [UniProtKB:P36969]
synonym: "GSHPx-4 (human)" EXACT [UniProtKB:P36969]
synonym: "glutathione peroxidase 4 (human)" EXACT [UniProtKB:P36969]
xref: Reactome:R-HSA-2142826 "PR:P36969 located_in GO:0005829"
xref: UniProtKB:P36969
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008213 ! phospholipid hydroperoxide glutathione peroxidase
relationship: has_gene_template HGNC:4556 ! GPX4 (human)

[Term]
id: PR:O70325-1
name: phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial (mouse)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial that is encoded in the genome of mouse." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "mGPX4/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70325-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000035962 ! phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial

[Term]
id: PR:000008213
name: phospholipid hydroperoxide glutathione peroxidase
def: "A protein that is a translation product of the human GPX4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GPX4" EXACT PRO-short-label [PRO:DNx]
synonym: "GPx-4" BROAD [PRO:DNx]
synonym: "PHGPx" EXACT []
synonym: "GSHPx-4" BROAD [PRO:DNx]
synonym: "glutathione peroxidase 4" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:O70325-2
name: phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic (mouse)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic that is encoded in the genome of mouse." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "mGPX4/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70325-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000035963 ! phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic

[Term]
id: PR:P36969-2
name: phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic (human)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGPX4/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36969-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035963 ! phospholipid hydroperoxide glutathione peroxidase isoform Cytoplasmic

[Term]
id: PR:P36969-1
name: phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial (human)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGPX4/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36969-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035962 ! phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial

[Term]
id: PR:O70325-3
name: phospholipid hydroperoxide glutathione peroxidase isoform Nuclear (mouse)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Nuclear that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:O70325]
comment: Category=organism-sequence.
synonym: "mGPX4/iso:Nuclear" EXACT PRO-short-label [PRO:DNx]
synonym: "phospholipid hydroperoxide glutathione peroxidase isoform nGPx4 (mouse)" EXACT [UniProtKB:O70325]
xref: UniProtKB:O70325-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000034128 ! phospholipid hydroperoxide glutathione peroxidase isoform Nuclear

[Term]
id: PR:000034128
name: phospholipid hydroperoxide glutathione peroxidase isoform Nuclear
def: "A phospholipid hydroperoxide glutathione peroxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70325-3 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "GPX4/iso:nuclear" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000008213 ! phospholipid hydroperoxide glutathione peroxidase

[Term]
id: PR:P36970-1
name: phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial (rat)
def: "A phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial that is encoded in the genome of rat." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "rGPX4/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36970-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000035962 ! phospholipid hydroperoxide glutathione peroxidase isoform Mitochondrial

[Term]
id: PR:O70325
name: phospholipid hydroperoxide glutathione peroxidase (mouse)
def: "A phospholipid hydroperoxide glutathione peroxidase that is encoded in the genome of mouse." [OMA:O70325, PRO:DAN]
comment: Category=organism-gene.
synonym: "Gpx4" RELATED Gene-based [UniProtKB:O70325]
synonym: "mGPX4" EXACT PRO-short-label [PRO:DNx]
synonym: "GPx-4 (mouse)" EXACT [UniProtKB:O70325]
synonym: "PHGPx (mouse)" EXACT [UniProtKB:O70325]
synonym: "GSHPx-4 (mouse)" EXACT [UniProtKB:O70325]
synonym: "glutathione peroxidase 4 (mouse)" EXACT [UniProtKB:O70325]
xref: UniProtKB:O70325
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008213 ! phospholipid hydroperoxide glutathione peroxidase
relationship: has_gene_template MGI:104767 ! Gpx4 (mouse)