[Term]
id: PR:P25409
name: alanine aminotransferase 1 (rat)
def: "An alanine aminotransferase 1 that is encoded in the genome of rat." [OMA:P25409, PANTHER:PTHR11751:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gpt" RELATED Gene-based [UniProtKB:P25409]
synonym: "Aat1" RELATED Gene-based [UniProtKB:P25409]
synonym: "Gpt1" RELATED Gene-based [UniProtKB:P25409]
synonym: "rGPT" EXACT PRO-short-label [PRO:DNx]
synonym: "ALT1 (rat)" EXACT [UniProtKB:P25409]
synonym: "GPT 1 (rat)" EXACT [UniProtKB:P25409]
synonym: "glutamic--alanine transaminase 1 (rat)" EXACT [UniProtKB:P25409]
synonym: "glutamic--pyruvic transaminase 1 (rat)" EXACT [UniProtKB:P25409]
synonym: "glutamate pyruvate transaminase 1 (rat)" EXACT [UniProtKB:P25409]
xref: UniProtKB:P25409
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008208 ! alanine aminotransferase 1
relationship: has_gene_template RGD:621720 ! Gpt (rat)

[Term]
id: PR:000047605
name: alanine aminotransferase 1, initiator methionine removed pyridoxal phosphate lysine 1 (human)
def: "An alanine aminotransferase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include pyridoxal phosphate lysine at position 314 of the amino acid sequence represented by UniProtKB:P24298. UniProtKB:P24298, 2-496, Lys-314, MOD:00128." [PRO:DNx, Reactome:R-HSA-70520]
comment: Category=organism-modification.
synonym: "hGPT/InitMet-/Pyrdox:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000123933, Lys-314, MOD:00128" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P24298, 2-496, Lys-314, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-70520 "PR:000047605 located_in GO:0005829"
is_a: PR:P24298 ! alanine aminotransferase 1 (human)
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000035942
name: alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1
def: "An alanine aminotransferase 1, initiator methionine removed form that has been N-terminal acetylated and contains covalently bound pyridoxal phosphate. Example: UniProtKB:P24298, 2-496, Ala-2, MOD:00050|Lys-314, MOD:00128." [PMID:1931970]
comment: Category=modification.
synonym: "GPT" RELATED [PMID:1931970]
synonym: "GPT/InitMet-/AcPyrdox:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000020057 ! alanine aminotransferase 1, initiator methionine removed form
relationship: has_part MOD:00050 ! N-acetyl-L-alanine
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine

[Term]
id: PR:P25409-1
name: alanine aminotransferase 1 isoform 1 (rat)
def: "An alanine aminotransferase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rGPT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P25409-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039110 ! alanine aminotransferase 1 isoform 1

[Term]
id: PR:P24298
name: alanine aminotransferase 1 (human)
def: "An alanine aminotransferase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P24298]
comment: Category=organism-gene.
synonym: "GPT" RELATED Gene-based [UniProtKB:P24298]
synonym: "AAT1" RELATED Gene-based [UniProtKB:P24298]
synonym: "GPT1" RELATED Gene-based [UniProtKB:P24298]
synonym: "hGPT" EXACT PRO-short-label [PRO:DNx]
synonym: "ALT1 (human)" EXACT [UniProtKB:P24298]
synonym: "GPT 1 (human)" EXACT [UniProtKB:P24298]
synonym: "glutamic--alanine transaminase 1 (human)" EXACT [UniProtKB:P24298]
synonym: "glutamic--pyruvic transaminase 1 (human)" EXACT [UniProtKB:P24298]
synonym: "glutamate pyruvate transaminase 1 (human)" EXACT [UniProtKB:P24298]
xref: UniProtKB:P24298
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008208 ! alanine aminotransferase 1
relationship: has_gene_template HGNC:4552 ! GPT (human)

[Term]
id: PR:Q6NYL5-1
name: alanine aminotransferase 2-like isoform 1 (zebrafish)
def: "An alanine aminotransferase 2-like (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NYL5-1." [PRO:DNx, UniProtKB:Q6NYL5]
comment: Category=organism-sequence.
synonym: "z-GPT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6NYL5-1
is_a: PR:Q6NYL5 ! alanine aminotransferase 2-like (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:Q8QZR5-1
name: alanine aminotransferase 1 isoform 1 (mouse)
def: "An alanine aminotransferase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mGPT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8QZR5-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039110 ! alanine aminotransferase 1 isoform 1

[Term]
id: PR:000035943
name: alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1 (human)
def: "An alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1 in human. UniProtKB:P24298, 2-496, Ala-2, MOD:00050|Lys-314, MOD:00128." [PMID:1931970]
comment: Category=organism-modification.
synonym: "hGPT" RELATED [PMID:1931970]
synonym: "hGPT/InitMet-/AcPyrdox:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P24298, 2-496, Ala-2, MOD:00050|Lys-314, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035942 ! alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1
relationship: has_part MOD:00050 ! N-acetyl-L-alanine
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine

[Term]
id: PR:Q6NYL5
name: alanine aminotransferase 2-like (zebrafish)
def: "An alanine aminotransferase 1 that is encoded in the genome of zebrafish." [OMA:Q6NYL5, PRO:DNx]
comment: Category=organism-gene.
synonym: "gpt" RELATED Gene-based [UniProtKB:Q6NYL5]
synonym: "gpt2" RELATED Gene-based [UniProtKB:Q6NYL5]
synonym: "gpt2l" RELATED Gene-based [UniProtKB:Q6NYL5]
synonym: "z-GPT" EXACT PRO-short-label [PRO:DNx]
synonym: "im:6791811" RELATED Gene-based [UniProtKB:Q6NYL5]
synonym: "ALT2 (zebrafish)" EXACT [UniProtKB:Q6NYL5]
synonym: "si:ch211-261f3.4" RELATED Gene-based [UniProtKB:Q6NYL5]
synonym: "GPT 2 (zebrafish)" EXACT [UniProtKB:Q6NYL5]
synonym: "glutamic--alanine transaminase 2 (zebrafish)" EXACT [UniProtKB:Q6NYL5]
synonym: "glutamic--pyruvic transaminase 2 (zebrafish)" EXACT [UniProtKB:Q6NYL5]
synonym: "glutamate pyruvate transaminase 2 (zebrafish)" EXACT [UniProtKB:Q6NYL5]
xref: UniProtKB:Q6NYL5
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000008208 ! alanine aminotransferase 1
relationship: has_gene_template ZFIN:ZDB-GENE-050302-11 ! gpt (zebrafish)

[Term]
id: PR:P24298-1
name: alanine aminotransferase 1 isoform 1 (human)
def: "An alanine aminotransferase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGPT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P24298-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039110 ! alanine aminotransferase 1 isoform 1

[Term]
id: PR:000039110
name: alanine aminotransferase 1 isoform 1
def: "An alanine aminotransferase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24298-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GPT/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008208 ! alanine aminotransferase 1

[Term]
id: PR:Q6NYL5-2
name: alanine aminotransferase 2-like isoform 2 (zebrafish)
def: "An alanine aminotransferase 2-like (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NYL5-2." [PRO:DNx, UniProtKB:Q6NYL5]
comment: Category=organism-sequence.
synonym: "z-GPT/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6NYL5-2
is_a: PR:Q6NYL5 ! alanine aminotransferase 2-like (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:000008208
name: alanine aminotransferase 1
def: "An alanine aminotransferase that is a translation product of the human GPT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ALT" BROAD [Wikipedia:Alanine_transaminase]
synonym: "GPT" EXACT PRO-short-label [PRO:DNx]
synonym: "AAT1" RELATED Gene-based []
synonym: "ALAT" BROAD [Wikipedia:Alanine_transaminase]
synonym: "ALT1" EXACT []
synonym: "GPT1" RELATED Gene-based []
synonym: "SGPT" BROAD [Wikipedia:Alanine_transaminase]
synonym: "GPT 1" EXACT []
synonym: "alanine transaminase" BROAD [Wikipedia:Alanine_transaminase]
synonym: "glutamic--alanine transaminase 1" EXACT []
synonym: "glutamic--pyruvic transaminase 1" EXACT []
synonym: "glutamate pyruvate transaminase 1" EXACT []
synonym: "serum glutamic-pyruvic transaminase" BROAD [Wikipedia:Alanine_transaminase]
synonym: "serum glutamate-pyruvate transaminase" BROAD [Wikipedia:Alanine_transaminase]
is_a: PR:000050219 ! alanine aminotransferase

[Term]
id: PR:Q8QZR5
name: alanine aminotransferase 1 (mouse)
def: "An alanine aminotransferase 1 that is encoded in the genome of mouse." [OMA:Q8QZR5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gpt" RELATED Gene-based [UniProtKB:Q8QZR5]
synonym: "Gpt1" RELATED Gene-based [UniProtKB:Q8QZR5]
synonym: "mGPT" EXACT PRO-short-label [PRO:DNx]
synonym: "ALT1 (mouse)" EXACT [UniProtKB:Q8QZR5]
synonym: "GPT 1 (mouse)" EXACT [UniProtKB:Q8QZR5]
synonym: "glutamic--alanine transaminase 1 (mouse)" EXACT [UniProtKB:Q8QZR5]
synonym: "glutamic--pyruvic transaminase 1 (mouse)" EXACT [UniProtKB:Q8QZR5]
synonym: "glutamate pyruvate transaminase 1 (mouse)" EXACT [UniProtKB:Q8QZR5]
xref: UniProtKB:Q8QZR5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008208 ! alanine aminotransferase 1
relationship: has_gene_template MGI:95802 ! Gpt (mouse)

[Term]
id: PR:000020057
name: alanine aminotransferase 1, initiator methionine removed form
def: "An alanine aminotransferase 1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "GPT/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008208 ! alanine aminotransferase 1
intersection_of: lacks_part PR:000021937 ! initiator methionine