[Term]
id: PR:000047596
name: glucose-6-phosphate isomerase, initiator methionine removed form (human)
def: "A glucose-6-phosphate isomerase (human) that has had the initiator methionine removed. UniProtKB:P06744, 2-558." [PRO:DNx, Reactome:R-HSA-70468]
comment: Category=organism-modification.
synonym: "hGPI/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000180537" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P06744, 2-558" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-70468 "PR:000047596 located_in GO:0005829"
xref: Reactome:R-HSA-6801495 "PR:000047596 located_in GO:0034774"
xref: Reactome:R-HSA-6801506 "PR:000047596 located_in GO:1904813"
xref: Reactome:R-HSA-6806478 "PR:000047596 located_in GO:0005576"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P06744 ! glucose-6-phosphate isomerase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06744
name: glucose-6-phosphate isomerase (human)
def: "A glucose-6-phosphate isomerase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P06744]
comment: Category=organism-gene.
synonym: "GPI" RELATED Gene-based [UniProtKB:P06744]
synonym: "hGPI" EXACT PRO-short-label [PRO:DNx]
synonym: "AMF (human)" EXACT [UniProtKB:P06744]
synonym: "NLK (human)" EXACT [UniProtKB:P06744]
synonym: "PGI (human)" EXACT [UniProtKB:P06744]
synonym: "PHI (human)" EXACT [UniProtKB:P06744]
synonym: "SA-36 (human)" EXACT [UniProtKB:P06744]
synonym: "neuroleukin (human)" EXACT [UniProtKB:P06744]
synonym: "sperm antigen 36 (human)" EXACT [UniProtKB:P06744]
synonym: "phosphohexose isomerase (human)" EXACT [UniProtKB:P06744]
synonym: "phosphoglucose isomerase (human)" EXACT [UniProtKB:P06744]
synonym: "autocrine motility factor (human)" EXACT [UniProtKB:P06744]
xref: UniProtKB:P06744
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008175 ! glucose-6-phosphate isomerase
relationship: has_gene_template HGNC:4458 ! GPI (human)

[Term]
id: PR:000008175
name: glucose-6-phosphate isomerase
def: "A protein that is a translation product of the human GPI gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AMF" EXACT []
synonym: "GPI" EXACT PRO-short-label [PRO:DNx]
synonym: "NLK" BROAD [PRO:DNx]
synonym: "PGI" EXACT []
synonym: "PHI" EXACT []
synonym: "Gpi1" RELATED Gene-based []
synonym: "SA-36" EXACT []
synonym: "neuroleukin" EXACT []
synonym: "sperm antigen 36" EXACT []
synonym: "phosphohexose isomerase" EXACT []
synonym: "phosphoglucose isomerase" EXACT []
synonym: "autocrine motility factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P06744-1
name: glucose-6-phosphate isomerase isoform h1 (human)
def: "A glucose-6-phosphate isomerase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06744-1." [PRO:DNx, UniProtKB:P06744]
comment: Category=organism-sequence.
synonym: "hGPI/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06744-1
is_a: PR:P06744 ! glucose-6-phosphate isomerase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06744-2
name: glucose-6-phosphate isomerase isoform h2 (human)
def: "A glucose-6-phosphate isomerase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06744-2." [PRO:DNx, UniProtKB:P06744]
comment: Category=organism-sequence.
synonym: "hGPI/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06744-2
is_a: PR:P06744 ! glucose-6-phosphate isomerase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045647
name: glucose-6-phosphate isomerase phosphorylated 1 (human)
def: "A glucose-6-phosphate isomerase (human) that has been phosphorylated at the position equivalent to Ser-185 of the amino acid sequence represented by UniProtKB:P06744-1. Example: UniProtKB:P06744-1, Ser-185, MOD:00046." [PMID:11004567, iPTMnet:P06744]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11004567). Status=unreviewed.
synonym: "hGPI/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06744-1, Ser-185, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06744 ! glucose-6-phosphate isomerase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens